Posted by admin on Jul 1, 2012 in |
In present study, eugenol (major functional component of essential oil of Syzygium aromaticum (clove), at 2% level (v/v) was incorporated in peanut oil based coating to get antimicrobial emulsion. Eugenol emulsion thus prepared was applied on grapes and strawberries. After applying emulsion, reference fruits were kept in corrugated fiber boxes for 8 days for shelf life studies under ambient conditions (temperature 24-27°C; Relative Humidity 55±5%). Fruit samples were checked for their visible microbiological growth every day and sensory evaluation of the coated samples was done up to the day of initiation of visible microbial growth. Results revealed that eugenol emulsions did not produced desirable effect on the shelf life of grapes and...
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Posted by admin on Jul 1, 2012 in |
Assessment of antimicrobial use can be performed by evaluating their use. Drug use evaluation is a performance improvement method that focuses on evaluation and improvement of drug use processes to achieve optimal patient outcomes. The objective of this study was to evaluate the rational use of ceftriaxone in Ayder referral Hospital, Mekelle-Ethiopia. Retrospective cross sectional study was used to assess rational use of ceftriaxone. The study was conducted by reviewing medication records of 296 patients who received ceftriaxone during hospitalization at Ayder referral Hospital from September 11, 2009 to September 10, 2010. A systematic sampling method was used to select inpatient prescriptions with ceftriaxone and patient cards were located based on the medical record number on the prescription papers. Data was collected by using structured format and evaluated against WHO criteria for drug use evaluation as per standard treatment guideline of Ethiopia. Most patients were dosed as 2 g/day (79.4%). The duration of therapy was found to be high in the range 2-7 days (51.69%). Ceftriaxone was mainly used...
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Posted by admin on Jul 1, 2012 in |
Argemone mexicana isan indigenous herb commonly known as Prickly poppy. It belongs to the family Papaveraceae. Argemone mexicana is noted to possess medicinal benefits in traditional system of medicine. During last few decades, there has been increasing interest in the study of medicinal properties of this plant and it is reported for Antimicrobial, Antidiabetic, Antioxidant and Hepatoprotective activity. The plant was also reported for other activities like Larvicidal activity, Wound healing activity, Cancer activity, Antihelmintic activity and Neuropharmacological studies. In light of these medicinal properties, this plant can be represented as a valuable source of medicinal compound. This study depicts the overall information about the ethnobotany, phytochemistry and pharmacological activities of the A....
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Posted by admin on Jul 1, 2012 in |
The antifungal, antimicrobial, antioxidant and cytotoxic activities of methylene chloride, methanol and hydroethanolic extracts of the leaves of Bridelia ferruginea and sterm bark of Pteleopsis suberosa were investigated against six Gram Positive and Gram negative strains bacteria and six species of Aspergilus. The antimicrobial activity was investigatedby the microtest method using p-iodonitrotetrazolium and theantifungal activity by measuringthe mycelial and sporulation inhibition. The phytochemical study was performed on Thin Layer Chromatography and antioxidant activity was assayed using qualitative and quantitative 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging test. The methanolic extract of Pteleopsis suberosa showed better Minimum Inhibitory Concentration against all the tested bacteria. The strongest activity was observed with the methanolic extract of Pteleopsis suberosa against S. aureus meticillin resistant with Minimum Inhibitory Concentration value of 78µg/ml. All extracts showed an interesting sporulation inhibitory percentage up to 60% whereas little to moderate inhibition was obtained against mycelial development (9.18 to 57.53%). The antioxidant activity of extracts increased in dose dependent manner. The methanolic and hydroethanolic extracts were the most active with inhibitory percentage...
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Posted by admin on Jul 1, 2012 in |
Medicinal plants represent a rich source of antimicrobial agents. The traditional medicine involves the use of different plant extracts of bioactive constituents. Ficus is a huge tropical deciduous or evergreen tree with more than 800 species. Purpose: Ficus benghalensis, Ficus religiosa, Ficus recemosa are important ingredients in many siddha, ayurveda and traditional formulations and used for the treatment of bacterial infections. An attempt was made to study the antibacterial effect of Ficus sp., by appropriate methods. Method: The acetone, methanol, ethylacetate extracts of Ficus benghalensis, Ficus religiosa, Ficus recemosa were evaluated for antibacterial activity against medically important bacteria Pseudomonas aeruginosa, Escherichia coli, Proteus vulgaris, Bacillus subtilis, Staphylococcus aureus. Phyto constituents of three plants were screened. The in-vitro antibacterial activity was performed by agar disc diffusion assay. Results: The plant extract that showed higher active antibacterial activity against tested bacterial strain was chosen analyse beta-lactamase inhibitory activity. Ficus sp. Showed more antibacterial activity on Escherichia coli, Staphylococcus aureus and Proteus vulgaris. Conclusion: Amongst the plant species screened, Ficus benghalensis extracts...
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