Posted by admin on Apr 30, 2017 in |
The multidrug-resistant strains are a major problem in the control of infections in hospitals. The smaller size of nanoparticles is gaining importance in research for the treatment of various diseases. The main objective of this study is synthesis of silver nanoparticle in eco-friendly manner without using any hazardous chemicals. Stable and spherical shaped nanoparticles Synthesized by using aqueous leaf extract of T. alata. This method offers a viable and an eco-friendly way for fabrication of benign nanoparticles as it is a simple and carried out at room temperature without any huge inputs in terms of energy and waste. It is advantageous over the microbial synthesis as it is carried out using in aqueous solutions at ambient temperature, without any toxic chemicals in lesser time and could be exploited for developing cost effective biosynthesis of Ag nanoparticles at a large scale. One more aim of this study is that analysis of antimicrobial activity of biogenic nanoparticles against disease causing human pathogens. Characterizations of nanoparticles were done by UV-Vis spectroscopy, FTIR,...
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Posted by admin on Apr 30, 2017 in |
Aims and objectives: Periodontal disease is the most common disease associated with microbial infection with destruction of supporting structures. The aim of the present study is compare the antimicrobial efficacy of plants of lythraceae family with hiora mouthwash in subjects with chronic periodontitis. Materials and methods: A total of 90 subjects were taken and randomly divided into three groups with 30 each. Group 1 received punica mouthwash, group 2 with lawsone mouth wash and group3 hiora mouth wash. Oral rinse technique was performed. Total microbial load and specific aerobic and anaerobic bacteria like Streptococci, staphylococci species, Agregatibacter actinomycetemcomitans, and Porphyromonas gingivalis were determined. Subjects were instructed to use given mouth washes twice daily with volume of 5ml/rinse for 30 sec and later post therapeutic samples were collected 1hr and 1week following drug usage and they were evaluated for total microbial load. Results: Statistical analysis was performed using chi square and one way ANOVA. All the three groups were compared at different time intervals which showed significant difference (P=0.000*) in...
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Posted by admin on Mar 31, 2017 in |
In this study, the plant Glycyrrhiza glabra was explored for the synthesis of silver nanoparticles (SNPs). The SNPs were characterised by ultra-violet-visible spectroscopy, FTIR analysis and scanning electron microscopy. SEM analysis revealed the formation of SNPs of average size of 46 nm with aqueous extract of G. glabra. The SNPs synthesised by aqueous extract of G. glabra showed strong antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa and significant inhibition to other bacteria and few fungi tested. The SNPs also exhibited potential anti cancer activity. The SNPs was observed to be nontoxic from a concentration of 500 µg/ml in vero cell line. The results document SNPs can be synthesised using aqueous plant extracts for applications in the biomedical...
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Posted by admin on Mar 31, 2017 in |
Now a day the exposure of multi-resistance human pathogens has challenged our existing defense to save human being. To minimize such alarming issue, identification of naturally-occurring antimicrobial agents from plant origin has become a realistic and powerful tool to the researchers. Therefore the aim of this study was to investigate the antimicrobial potential of the ethanolic extracts of different parts of Abelmoschus moschatus (A. moschatus) against some important human bacterial and fungal pathogens. Different parts (leaves, stem bark, fruits pulp and seeds) of A. moschatus were extracted with ethanol to get crude ethanolic leaves (LE), stem bark (SBE), fruits pulp (FPE) and seed extracts (SE). Antimicrobial activity of LE, SBE, FPE and SE were assessed by disk diffusion and serial dilution method. All the extracts showed moderate antimicrobial activity against all tested pathogens. Among the extracts LE was comparatively highly sensitive against all tested pathogens. In case of S. dyesenteriae and S. sonnei zone of inhibition of LE (26 and 28 mm diameter with MIC 31.25 and 62.5 µg/ml;...
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Posted by admin on Mar 31, 2017 in |
A major part of the total population in developing countries still uses traditional folk medicine obtained from plant resources. Chemical substances used for prevention of dental caries are known to have many side-effects. Thus, natural products should be explored for their anticaries action. Present study evaluate the antimicrobial effect of alcoholic and aqueous extracts of Magnifera indica leaves against oral dental pathogens Streptococcus mutans, Staphylococcus aureus. Ethanolic extract was found to be more effective and dose dependent against both pathogens. Phytochemical and antioxidative study was also performed using various methods of testing on the aqueous and ethanolic extracts for the presence of phenols, alkaloids, saponins, terpenoids, flavonoids, tannins and reducing sugar. Both leaf extracts showed higher anti oxidative capacity and phytochemicals content like alkaloids and steroids which are active antimicrobial components in plants. Present investigation provides preliminary information for using mango leaf extracts in the prevention of oral diseases such as dental...
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