Posted by admin on Aug 1, 2013 in |
Traditional knowledge and ethno–botanical use of plants have been widely acknowledged all over the world. In the present scenario, emergence of multiple drug resistance to human pathogenic organisms, this has necessitated a search for new antimicrobial substances from other sources including plants. Combretum albidum, a traditional medicinal liana, used by rural peoples, villagers and tribals residing in different parts of Maharashtra, Tamil Nadu and Kerala, to treat various ailments. The Muthuvans, Chinnar tribe of Idukki district, Kerala is using stem bark of this plant as a remedy for Jaundice. The present study carried out to check the antimicrobial activity of water and methanol extracts of stem bark of C. albidum. The result showed significant antibacterial activity against Escherichia coli, Klebsiella pneumonia, Proteus mirabilis, Pseudomonas aeruginosa, Bacillus subtilis and Salmonella...
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Posted by admin on Aug 1, 2013 in |
Ethanol extract of the leaves of Taxus baccata, Phyllanthus debilis, Plectranthus amboinicus were studied for their antimicrobial property against multidrug resistant bacterial strains (MDR) from clinical specimens. Of these three plants, the most potent antimicrobial plant was Phyllanthus debilis followed by Taxus baccata (MIC range 80 – 400μg/ml) having broad spectrum activity, whereas Plectranthus amboinicus had no effect against MDR isolates. Taxus baccata and Phyllanthus debilis can be used as antimicrobial agents. Further confirmation needs ethano-pharmcological...
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Posted by admin on Jul 1, 2013 in |
A series of some New 2, 3-dihydro-1, 5-benzodiazepines has been synthesized using condensation reaction of o-phenylenediamine and various substituted chalcones in presence of DMF as solvent and screening of antibacterial and antifungal activities of synthesized...
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Posted by admin on Jul 1, 2013 in |
The present study was designed to compare the antioxidant, antimicrobial and thrombolytic effects of the Lannea coromandelica bark and leave extracts. After the initial phytochemical screening, the ethanolic fractions of the L. coromandelica bark and leaves were partitioned by solvents of different polarity. Methods used to evaluate the antioxidant potential of the extracts were total phenolic content, total flavonoid content, free radical scavenging capacity, total antioxidant capacity and reducing power assay. Total phenol and total flavonoid contents were found to be the highest for bark and leaves in the ethyl acetate fraction and lowest in the n-Hexane fraction. In DPPH free radical scavenging test, the lowest IC50 value was found in the ethyl acetate fraction of the bark and leaf, resulting IC50 value of 3.8±0.14 μg/ml and 6±0.32 μg/ml respectively. In the same vein, ethyl acetate fraction of both leaf and bark showed the highest antioxidant capacity and reducing power. Reducing power of both bark and leaves were found to be concentration dependent and most prominent was observed with...
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Posted by admin on Jun 1, 2013 in |
As part of a research initiative to evaluate plants used for their nutritional and herbal values, the antimicrobial activity of Solanum Melongena’s fruit and Moringa oleifera’s leaveswere investigated. Each plant part was subjected to selective extraction using solvents of varying polarity: n-C6H14, CH2Cl2, EtOAc and CH3CH2OH. The n-C6H14 and CH3CH2OH extract of these two plants were tested for their antimicrobial activity at three different concentrations of 5%, 10% and 20% of crude extracts against three pathogenic bacterial strains: Eschericia coli, Staphyloccocus aureus and Klebsiella pneumoniae using the Disc diffusion assay. Both n-C6H14 and CH3CH2OH extracts showed antibacterial activity at a higher concentration of 20% of crude extract. The order of bacteria susceptibility to Moringa oleifera extract been S. aureus > K. pneumoniae > E. coli whereas that for Solanum Melongena extract been S. aureus > E. coli > K. pneumonia. The area of zone of inhibition ranges from 44.15 mm2 to 53.55 mm2. These investigations suggest that the extracts of Moringa oleifera and Solanum Melongena can be used as...
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