Posted by admin on May 18, 2018 in |
High fat diet and High fructose intake is the predominant lifestyle change that increased the epidemic of type-2 diabetes. HFD+HF feeding leads to oxidative stress mediated T2D through production of free radicals and decrement of antioxidant enzymes. Our present study focussed on the curbing effect of gymnemic acid on high fat diet and high fructose feeding induced oxidative stress mediated Type 2 diabetes mellitus. A total of 30 rats, 18 diabetic and 12 normal wistar rats were used for this study. Rats were HFD+HF fed and confirmed diabetic then animals were orally treated with gymemic acid (150 mg/kg body weight) daily for 30 days. Gymnemic acid supplementation effectively lowered the blood glucose and lipid levels expect HDL in HFD and HF fed diabetic rats. Free radical scavenging ability of gymnemic acid lead to the decrement of free radicals and thereby preventing macromolecular damage. Islets possess significantly lesser antioxidant potential when compared to other tissues and easily susceptible to oxidative stress under T2D condition. GPx a key antioxidant which can...
Read More
Posted by admin on Apr 30, 2018 in |
Objective: To evaluate the anticonvulsant activity of aqueous extract of Eupatorium birmanicum DC. leave (EB) alone and in combination with ethosuximide against seizure induced by PTZ in albino mice. Method: Aqueous extract of EB leaves was prepared using Soxhlet apparatus. The albino mice were fed with EB at 3 doses (200, 400 & 800 mg/kg). One hour after feeding, pentylenetetrazole (PTZ) was given at a dose of 60 mg/kg, s.c. after dissolving in distilled water, at the nape of the neck at a volume of 5 ml/kg to produce convulsion. The animals were observed for upto 30 mins after the PTZ challenge for onset of myoclonic spasm and clonic convulsion. The time of onset of myoclonic spasm and clonic convulsion were noted in seconds. Sub-anticonvulsant dose of ethosuximide was also determined and the effect of its combination with the most effective dose of EB tested. Results: The aqueous extract of Eupatorium birmanicum at doses 200mg/kg, 400mg/kg and 800 mg/kg significantly (p<0.001) increased the latency of onset of myoclonic spasm...
Read More
Posted by admin on Apr 30, 2018 in |
This study was conducted to investigation the effect of humic acid and salicylic on oil yield and flavonoids glycoside of safflower plant (Carthamus tinctorius L.) grown in Iraq. After soil preparation the plant seeds were cultivated during winter growing seeds at 2015-2017 at Karbala region, South Baghdad in Iraq. The humic acid was applied at 1000, 2000 and 4000 mg/lit conception as organic flower fertilizes while the application of salicylic acid was used 50, 100 and 200 mg/lit. Twister application of bath humic and salicylic acids were done at vegetable growth stage all treatment were arranged by according randomized complete block design (RCBD) flower leaves or petals ethylic extract was done by used Soxhlet apparatus, the use HPLC his prefect liquid climter to determine the type and concentration of Pt flavonoids glycoside. Also the seed oil was obtained by expression mthai. The redaction were infeed to the S2 F3 treatment (100 mgl-1 of salicylic acid with 400 mgL-1 of humic acid) was gave height value of oil yield and...
Read More
Posted by admin on Mar 31, 2018 in |
Genus Urtica belongs to family Urticaceae and commonly known by name of nettles. The plant Urtica has been used as a folk medicine and as a food source from a long time. It has been used frequently for its medicinal properties since the Bronze age (3000 – 2000 B.C.) as a traditional herbal remedy in treatment of variety of diseases as rheumatism gouts, nephritis, haematuria, jaundice, menorrhagia, anemia, eczema, arthritis. It has been used for a long time as first-aid remedy in treatment of infirmities in case of bites and stings, burns, hives and breast feeding problems. Phytochemicals evaluation of the plant revealed presence of various chemical compounds like phytosterols, saponins, flavonoids, phenolic acids, tannins, proteins and amino-acids that showed beneficial potential of the plant to get commercially cultivated and get used for the natural drugs and medicine. The plant has been reported to have various pharmacological activities as antioxidants, analgesic, anti-inflammatory, anti-ulcer, anti-viral, immuno-modulatory, hepatoprotective, anti-diabetic, anti-colitis and anti-cancer...
Read More
Posted by admin on Feb 28, 2018 in |
Single cell protein is a protein extracted from cultured algae, yeasts, or bacteria and used as a substitute for protein-rich foods, especially in animal feeds or as dietary supplements. Many types of animal feeds contain single cell proteins. It can also be called biomass, bioprotein or microbial protein. The word single cell protein which was coined in the 1960 is considered to be appropriate since most of the microorganisms grow as single or filamentous individuals. Besides its high protein content (about 60 – 82% of dry cell weight), single cell protein also contains fats, carbohydrates, nucleic acids, Vitamins and minerals. According to various investigations on the fermentations of fruit juices, it has been reported that they could be used as feed-stocks for the production of single cell protein (SCP) based on their level of sugar and ability to support the growth of yeasts. Single cell proteins thus, are the dried cells of microorganisms such as yeast that could be grown in large-scale culture systems for use as protein for...
Read More
