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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

Inclusion in Web of Science (Thomson Reuters) - ESCI
Projected Impact Factor (2015): 1.11 , ICV (2015): 90.24
Five-Year Projected Impact Factor: 2.60

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Volume 8 (2017) - Issue 7, July

Review Articles

 
Title
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1.

A REVIEW ON NANOPARTICLE CROSS-LINKED COLLAGEN SHIELD FOR SUSTAINED DELIVERY OF DRUG IN GLAUCOMA

Glaucoma is a disease of the optic nerve. Progressive damage of the optic nerve will causes irreversible reduction in visual acuity; it leads to visual field loss and blindness. The main treatment of glaucoma is the reduction of intraocular pressure. Current therapy involves frequent administration of eye drops which results in poor patient adherence and therapeutic outcomes. This review is focusi...

P. M. Kukkar*, A.D. Savkare, M. R. Bhavsar and V. D. Gholap

MVP Samaj’s College Of Pharmacy, Nashik, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).2731-39

2731-2739

1127

485

2.

A COMPREHENSIVE REVIEW ON CANCER AND ANTICANCER HERBAL DRUGS

Cancer is a major public health burden in both developed and developing countries. It is an abnormal growth of cells in body that can lead to death and globally the numbers of cancer patients are increasing day by day. There are several medicines available in the market to treat the various types of cancer but no drug is found to be fully effective and safe. Herbal medicines have a vital role in t...

R. K. Bijauliya *, S. Alok, M. Singh and S. B. Mishra

Institute of Pharmacy, Bundelkhand University, Jhansi Uttar Pradesh, India

DOI: 10.13040/IJPSR.0975-8232.8(7).2740-61

2740-2761

1249

373

3.

EFFLUX PUMP INHIBITORS: ENHANCE THERAPY AND CAUTERIZE TUBERCULOSIS

The requirement of drug resistance regularly to plague Tuberculosis control, with vast increase in the spreading of MDR-TB. It can act as a gateway to XDR-TB and then emphasis on the urgency for new drug development and optimal treatment option for Tuberculosis therapy. In this study, we assess the recommending for using Rifabutin (RFB) instead of rifampicin (RIF). The objective of this study and ...

Gyanendra Singh* and A. K. Srivastava

Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology, (Banaras Hindu University), Varanasi, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).2762-67

2762-2767

1105

201

4.

LIQUISOLID TECHNIQUE: A REVIEW

Dissolution of drug and its release from the dosage form have basic impact on bioavailability. Bioavailability depends on solubility of drug. Solubility is major challenge for the pharmaceutical industry with the developments of new pharmaceutical products. There are several approaches for solubility enhancement which includes micronization, Nanonisation, use of salt forms, use of surfactant, soli...

Anand D. Savkare, Malavi R. Bhavsar *, Vishal D. Gholap and Pooja M. Kukkar

MVP Samaj’s College of Pharmacy, Nashik, Maharashtra, India

DOI: 10.13040/IJPSR.0975-8232.8(7).2768-75

2768-2775

901

208

5.

BIOMARKERS – ITS ROLE IN MEDICINE

Biomarker is a measurable indicator of the severity or presence of some disease state. It is introduced into an organism as a means to examine organ function or other aspects of health. Biomarkers play a major role in medicinal biology. They help in early diagnosis, disease prevention, drug target identification, drug response etc. Several biomarkers have been identified for many diseases such as ...

S. Pahwa*, V. Sharma and V. Arora

Lloyd Institute of Management and Technology, Greater Noida, Uttar Pradesh, India

DOI: 10.13040/IJPSR.0975-8232.8(7).2776-88

2776-2788

1052

173

6.

COMPLICATIONS ASSOCIATED WITH ANGIOPLASTY

For certain people, heart disease treatment can be achieved without surgery. Angioplasty and stend placement are the common, non-surgical procedures that can be used to open the blocked heart arteries. This technique involves five different procedures including: Percutaneous coronary angioplasty, Peripheral angioplasty, Carotid angioplasty, Renal angioplasty and Venous angioplasty. Carotid angiopl...

Maryam Fatima* and Zainab Mahveen

Department of Pharmacology, Deccan School of Pharmacy, Hyderabad, India

DOI: 10.13040/IJPSR.0975-8232.8(7).2789-97

2789-2797

153

78

7.

REVIEW ON THE FIXED DOSE COMBINATION DRUGS AND THEIR INCOMPATIBILITIES

Incompatibility is an undesirable reaction that occurs between drugs, excipients, or with container. This may be therapeutic, chemical and physical incompatibility. Fixed dose combination provides challenge in product development due to incompatibility of two drugs. So severe degradation of drug in presence of each other. Formulation and stability difficulties arise with incompatible combination. ...

Anand D. Savkare* and Rekha K. Wakhare

Department of Pharmaceutics, MVP Samaj’s college of Pharmacy Nashik, Maharashtra, India

DOI: 10.13040/IJPSR.0975-8232.8(7).2798-07

2798-2807

146

97

8.

REGULATORY ASPECTS FOR IMPURITY PROFILING OF PHARMACEUTICAL PRODUCTS: AN OVERVIEW

Pharmaceutical impurities are the organic and inorganic unwanted chemicals which are found in active pharmaceutical ingredient after synthesis or develop during formulation development. These impurities severely affect the safety and efficacy of developed pharmaceutical product. Impurity profiling detects and quantifies the levels of organic and inorganic impurities and thereby helps in better mon...

Gourav Ruhela and Deepak Kaushik*

Department of Pharmaceutical Sciences, M.D. University, Rohtak, Haryana, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).2808-14

2808-2814

171

66

9.

TREATMENT OF ENTERIC FEVER AND UNDIFFERENTIATED FEBRILE ILLNESS IN NEPAL: A REVIEW

Typhoid fever and paratyphoid fever (also known as enteric fever, but collectively referred here as typhoid Fevers) are severe systemic illnesses characterized by sustained fever and abdominal symptoms. Treatment of typhoid fever becomes difficult by the development of multi-drug resistant of typhoid organisms especially to ampicillin, trimethoprim-sulfamethoxazole and chloramphenicol. In recent y...

Raj Kumar Thapa* and Dharma Prasad Khanal

Department of Pharmacy , G.P.O. Box 252, (Kathmandu, Nepal) Patan Hospital, Lalitpur, Nepal.

DOI: 10.13040/IJPSR.0975-8232.8(7).2815-18

2815-2818

157

64

Research Articles

 
Title
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10.

β-CYFLUTHRIN-INDUCED IMPAIRMENT IN NEUROTRANSMITTERS, TESTICULAR FUNCTION AND GENE EXPERISSIONS OF MALE RATS: THE PROTECTIVE ROLE OF OMEGA-3

The present study was designed to evaluate the protective effect of omega-3 against β-cyfluthrin (β-cyf)-induced neurotransmitters’ impairment, oxidative damage, testicular toxicity and genotoxicity. Adult male Wistar rats were divided equally into four groups: Group (I): Control, Group (II): β-cyf (5 mg/kg body weight/day), Group (III): omega-3 (400 mg/kg body weight/da y) + β-cyf (5 mg/kg ...

Heba M. Abdou*, Nema A. Mohamed, Doaa Awad and Ibtehal El-Qazaz

Department of Zoology, Faculty of Science, Alexandria University, Alexandria, Egypt.

DOI: 10.13040/IJPSR.0975-8232.8(7).2819-31

2819-2831

987

174

11.

THE RELATIONSHIP BETWEEN INTESTINAL PROTECTIVE MARKERS AND SERUM ENDOTHELIN-1 CONCENTRATIONS IN LOW BIRTH WEIGHT INFANTS WITH HYPOXIC-ISCHEMIC ENCEPHALOPATHY

Perinatal hypoxia results in poor circulation in internal organs, causing damage to the intestinal mucosa. Here, we aimed to evaluate the role of endothelial vasoconstrictor function in the formation of the intestinal mucous barrier in low-birth-weight neonates with hypoxic-ischemic encephalopathy (HIE). We comparatively analysed the concentrations of specific intestinal protective markers, i.e., ...

N. F. Panakhova, A. S. Hajiyeva, S. A. Huseynova *, S. S. Hasanov and N. N. Hajiyeva

Azerbaijan Medical University, K. Farajova Scientific Research Institute of Pediatry, Baku, Azerbaijan.

DOI: 10.13040/IJPSR.0975-8232.8(7).2832-38

2832-2838

1126

121

12.

NEW INHIBITORS AGAINST accD3 GENE OF MYCOBACTERIUM TUBERCULOSIS, IN-SILICO STUDY AND IN -VITRO APPLICATION

Mycobacterium tuberculosis (Mtb) is a pathogenic bacteria species in the genus Mycobacterium and the causative agent of most cases of tuberculosis. Tuberculosis (TB) is the leading cause of death in the world from a bacterial infectious disease. This antibiotic resistance strain lead to development of the new antibiotics or drug molecules which can kill or suppress the growth of Mycobacterium tube...

Asra’a A. Abdul-Jalil* and Zahra M. Al-Khafaji

College of Science, University of Anbar, Baghdad, Iraq

DOI: 10.13040/IJPSR.0975-8232.8(7).2839-48

2839-2848

1035

134

13.

THE EFFECT OF THYMOQUINONE ON THE miRNA PROFILE OF MCF-7 BREAST CANCER CELLS

Background and aim: Thymoquinone (TQ), which is the most bioactive component of Nigella sativa (Black cumin), exhibits anticancer characteristics based on cell culture and experimental animal studies. However, molecular action mechanisms of these effects are not clear. MicroRNAs (miRNAs), small non-coding RNAs of approximately 22 nucleotides,  are an emerging class of gene expression modulators w...

Beyza Saraçligil *, Bahadır Öztürk, Ş. Buket Bozkurt and Yasemin Kahveci

Department of Biochemistry, Faculty of Medicine, Selçuk University, Konya, Turkey

DOI: 10.13040/IJPSR.0975-8232.8(7).2849-52

2849-2852

1035

147

14.

FORMULATION AND EVALUATION OF DILTIAZEM HCl FAST DISSOLVING TABLETS USING DIFFERENT CO-PROCESSED EXCIPIENTS BY DIRECT COMPRESSION METHOD

The aim of present work was to prepare Diltiazem HCl Fast Dissolving tablets by Direct compression method because of their convenience in administration and suitability for patients having dysphagia using Co-processed excipients-Disintequik MCC25, Disintequik MCC, Lubritose MCC, Lubritose SD, Lubritose AN, NF Fast flow Lactose Monohydrate modified spray dried. The Prepared powdered blend and table...

M. Sunitha Reddy*, Niveditha Kore and S. Muhammad Fazal Ul Haq

Centre for Pharmaceutical Sciences, Institute of Science and Technology, Jawaharlal Nehru Technological University, Kukatpally, Hyderabad, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).2853-61

2853-2861

991

239

15.

PHYTOCHEMICAL CONSTITUENTS AND ANTI-OXIDATIVE PROPERTIES OF LANDOLPHIA HEUDELOTTI ROOTS

The roots of Landolphia heudelotti are employed in traditional medicine for the treatment of a plethora of ailments. In this study, the antioxidant activity and bioactive constituents of the methanol root extract were investigated. Fourteen known compounds including a lignan, neolignans, sesquilignans, a coumarin and an aromadendrane sesquiterpene were isolated from the root extract. The structure...

E. A. Mireku, A. Y. Mensah *, M. L. K. Mensah, I. K. Amponsah and D. N. Mintah

Department of Pharmacognosy, Faculty of Pharmacy and Pharmaceutical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana

DOI: 10.13040/IJPSR.0975-8232.8(7).2862-66

2862-2866

153

107

16.

ANALGESIC AND ANTIPYRETIC ACTIVITIES OF ETHANOLIC EXTRACT OF BAMBUSA ARUNDINACEA LEAVES

To study the analgesic and antipyretic activities of ethanolic extract of Bambusa arundinacea leaves (EEBA) in rats by using models tail immersion test, hot plate test and brewer’s yeast pyrexia model. Methods: The dried powdered leaves were extracted with ethanol and the resultant extract was subjected for phytochemical investigation to identify different phytoconstituents. Analgesic activity o...

T. Jawaid *, M. Kamal and J. Singh

Department of Pharmacology, College of Medicine, Dar Al Uloom University, Al Mizan St, Al Falah, Riyadh, Kingdom of Saudi Arabia

DOI: 10.13040/IJPSR.0975-8232.8(7).2867-72

2867-2872

128

80

17.

HISTOPATHOLOGICAL ALTERATIONS IN KIDNEY DUE TO THE EFFECT OF VARIOUS STAGES OF NAGABHASMA (LEAD) PREPARATION

Background: Nagabhasma is a lead-based Ayurvedic medicine. Numerous reports indicate the toxic effects of lead used in this preparations on various systems of our body. But Ayurveda claims that the toxic effect of lead gets nullified thereby acquiring the medicinal property by following stringent and traditional method of preparation. Objectives: Therefore, the present study is designed to evaluat...

L. S. Quadros and K. M. R. Bhat *

Department of Anatomy, Ras Al Khaimah College of Medical Sciences, RAK Medical and Health Sciences University, Ras Al Khaimah, UAE

DOI: 10.13040/IJPSR.0975-8232.8(7).2873-78

2873-2878

126

54

18.

ACID AMINE COUPLING OF (1H-INDOLE-6-YL)PPIPERAZIN-1-YL)METHANONE WITH SUBSTITUTED ACIDS USING HATU COUPLING REAGENT AND THEIR ANTIMICROBIAL AND ANTIOXIDANT ACTIVITY

Acid amine coupling of 1H-indol-6-yl(piperazin-1-yl) methanone with different acids has been synthesized in presence of HATU reagent, DIPEA base with DMF solvent at 45 °C 30 mins to yield Indole piperzine derivatives 3a-j. The structures of all the synthesized compounds have been characterised by elemental analysis and spectral studies like 1H-NMR and LCMS. Some selected Indole piperazine derivat...

S. M. Mallikarjuna, C. Sandeep and B. Padmashali *

Department of Chemistry, Sahyadri Science College (Autonomous), Shimoga, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).2879-85

2879-2885

133

70

19.

TREATMENT WITH ORAL METAFOL L APPEARS TO PROMOTE RESTORATION OF LOST CUTANEOUS SENSATION IN DIABETIC PERIPHERAL NEUROPATHY

The purpose of this research work is to determine whether Metafol-L improves sensory neuropathy in patient with Type 2 diabetes or not. In patients with diabetes mellitus, prolonged hyperglycemia can result in peripheral neuropathy (pain and/or loss of sensation in the extremities). Neuropathy issues may be related to Vitamin B deficiencies; therefore, the supplementation of Vitamin B12, Vitamin B...

Pallavi Shende * and Sudarshan S Joshi

Department of Pharmaceutics, Allana College of Pharmacy, University of Pune, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).2886-92

2886-2892

142

75

20.

DIFFERENT TYPE OF CELL DEATH INDUCTION BY CURCUMIN, ARSENIC TRIOXIDE AND DEGRASYN (WP1130) IN HUMAN MULTIPLE MYELOMA CELLS

Curcumin has been shown to inhibit the activation of nuclear factor-κB (NF-κB), which is closely linked to chemo-resistance, in multiple myeloma cells. Malignant cells of this kind typically develop progressive multidrug resistance. Our aim was to investigate new possibilities for overcoming this resistance by suppressing cell signaling pathways. MTT-dye reduction assay was used to evaluate the ...

K. Kaloyanov *, P. Donchev, M. Yotova, G. Momekov and S. Konstantinov

Faculty of Pharmacy, Medical University of Sofia, Sofia, Bulgaria

DOI: 10.13040/IJPSR.0975-8232.8(7).2893-99

2893-2899

165

57

21.

SOLUBILITY ENHANCEMENT OF BCS CLASS II DRUG USING LYOPHILISATION TECHNIQUE AND DETERMINATION OF BIOAVAILABILITY IN ANIMALS USING CATALEPSY MODEL

Ziprasidone HCl is a newly introduced atypical antipsychotic drug. It has its own unique multi receptor binding affinity. This makes it a unique special choice of antipsychotic agent.  It mainly acts as antagonist of D2 dopamine receptors as and 5HT2A (serotonin, 5HT, 5-hydroxytryptamine) receptors. It is pinkish brown colored powder having very low solubility in water (21.12 mg/L). The main purp...

M. P. Ratnaparkhi * and P. D. Chaudhari

Marathwada Mitra Mandal’s College of Pharmacy, Thergaon (Kalewadi), Pune, Maharashtra, India

DOI: 10.13040/IJPSR.0975-8232.8(7).2900-09

2900-2909

114

68

22.

ASSESSMENT OF NUTRITIONAL CONSTITUENTS AND IN VITRO ANTIOXIDANT CAPACITY OF METHANOLIC STEM EXTRACT OF CARALLUMA ATTENUATA

The main objective of the present study includes the assessment of nutritional constituents and anti-oxidant activity of methanolic stem extract of Caralluma attenuata by in-vitro methods. In the present investigation the author has identified the phytochemical constituents which have nutritional importance by specific chemical tests, thin layer chromatography, atomic absorption spectroscopy for C...

P. Mounika, M. Vijaya Jyothi *, Y. Rajendra Prasad, C. Naresh Babu and S. Triveni

Department of Pharmaceutical Chemistry, Raghavendra Institute of Pharmaceutical Education and Research, K.R. Palli cross, Ananthapuramu, Andhra Pradesh, India

DOI: 10.13040/IJPSR.0975-8232.8(7).2910-15

2910-2915

117

61

23.

PHYTOCHEMICAL ANALYSIS OF METHANOLIC EXTRACT OF SEEDS OF MUCUNA PRURIENS BY GAS CHROMATOGRAPHY MASS SPECTROMETRY

Mucuna pruriens is a climbing legume used in the treatment of various ailments. It is commonly known as Cowitch or velvet bean. Traditionally, it was used in treating male infertility. The main aim of this study was to identify the bioactive materials present in the methanol extract of Mucuna pruriens seeds by Gas Chromatography Mass Spectrometry (GC-MS) technique. The analysis by GC-MS reveals th...

J. Saikarthik *, S. Ilango, J. Vijayakumar and R. Vijayaraghavan

Saveetha Medical College and Hospital, Saveetha University, Chennai, Tamil Nadu, India

DOI: 10.13040/IJPSR.0975-8232.8(7).2916-21

2916-2921

148

97

24.

ORAL EXTENDED RELEASE DRY SUSPENSION OF PARACETAMOL LOADED MICROSPHERES

Background: A novel reconstitutable suspension of Paracetamol loaded microspheres was prepared using ethyl cellulose as a release controlling polymer and by solvent evaporation technique for the relief of osteo-arthritic pain. Objective: The formulation was developed to enhance patient compliance of population suffering from dysphagia or have difficulty in swallowing oral solid dosage forms like t...

Anuradha R. Mhadgut * and Vivek V. Nalawade

VES College of Pharmacy, Hashu Advani Memorial Complex, Behind Collector Colony, Chembur (E), Mumbai, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).2922-31

2922-2931

142

101

25.

ANTIOXIDANT, ANTIBACTERIAL EFFECTS OF SOLANINE ISOLATED FROM SOLANUM NIGRUM AND ITS CYTOTOXIC ACTIVITY ON THE HEP-2 AND AGS CELL LINES

Solanum nigrum is a well known traditional medicinal plant. This study was intended to isolated active compound from the Solanum nigrum leaf. Solanine were isolated and purified from leaves of Solanum nigrum by using acid extraction along with alkaline precipitation methods and results shows that leaves of Solanum nigrum found to good sources of Steroidal glycol-alkaloids together with their struc...

A. Rajalakshmi and A. Jayachitra*

Department of Plant Biotechnology, School of Biotechnology, Madurai Kamaraj University, Madurai, Tamil Nadu, India

DOI: 10.13040/IJPSR.0975-8232.8(7).2932-39

2932-2939

145

75

26.

OPTIMIZATION OF TETRABENAZINE TABLET FORMULATION TO MEET THE REQUIRED DISSOLUTION PROFILE AND CONTENT UNIFORMITY

An approach to determine the relationship between independent process variables and their two level four factor partial factorial design was adopted, composite of experiment design was applied to optimize a tablet formulation of Tetrabenazine (TBZ) Tablets 25mg containing high percentage of Lactose Anhydrous, Sodium starch Glycolate, Magnesium Stearate and Starch / Lactose Ratio. The particle size...

S. Roy*, K. Kannan and Amol Choulwa

Glenmark Pharmaceutical Limited, Andheri East, Mumbai, Maharashtra, India

DOI: 10.13040/IJPSR.0975-8232.8(7).2940-48

2940-2948

127

62

27.

SOFT CHEMICAL SYNTHESIS OF Ag DOPED ZnO NANOPARTICLES: ANTIMICROBIAL ACTIVITY AND IN VIVO ACUTE NANOTOXICOLOGICAL IMPACT ON SWISS ALBINO MICE

In this research work Zn1-xAgxO1-δ (where x = 0.05, 0.10, 0.15 and 0.20) nano powders were synthesized via simple soft chemical method using corresponding metal nitrates and alkali precipitant. Sodium hydroxide was used as a precipitant during the synthesis. The prepared samples were characterized using X-ray diffraction, FTIR spectroscopy, particle size analysis, SEM, EDAX analysis and TEM. The ...

P. Suresh Kumar and A. Samson Nesaraj *

Department of Science and Humanities, (Chemistry), Karunya University, Karunya Nagar, Coimbatore, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).2949-59

2949-2959

126

85

28.

AN EFFICIENT SYNTHESIS OF 2-AMINOBENZOTHIAZOLE AND ITS DERIVATIVES IN IONIC LIQUIDS

The 2-aminobenzothiazole moiety and its derivatives have immense importance in medicinal and pharmaceutical chemistry as a potent biologically active molecules. The synthesis of 2-aminobenzothiazole derivatives carried out from substituted phenyl thiourea which is synthesized by substituted aniline in ionic liquid (1-butyl-3-methylimidazolium) bisulphate ([BMIM] + [HSO4]-), (1-butyl-3-methylimidaz...

D. K. Jangid *, A. Guleria, S. Dhadda, K. Yadav, P. G. Goswami and C. L. Khandelwal

Centre of Advanced Study, Department of Chemistry, University of Rajasthan, Jaipur, Rajasthan, India

DOI: 10.13040/IJPSR.0975-8232.8(7).2960-64

2960-2964

164

58

29.

POST OPERATIVE DELIRIUM IN ELDERLY PATIENTS UNDERGOING HIP SURGERY: DIAZEPAM VERSUS HALOPERIDOL

Post-operative delirium is transient global disorder showing reduced cognition, altered consciousness and psychomotor activity as well as deranged sleep-wake cycle.  For elderly patients undergoing hip surgery, the reported incidence varies from 16% to 62% with average rate of 35%.  Pharmacotherapy management of post-operative delirium may entail use of drugs belonging to groups like sedatives, ...

Mittal B. Dave *, Urmi M. Dave, Ravikiran S. Lagali and Kashyap V. Ramoliya

PDU Medical College, Civil Hospital, Jamnagar Road, Rajkot, Gujarat, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).2965-67

2965-2967

139

68

30.

AN IN VITRO COMPARATIVE STUDY ON ANTIOXIDANT, ANTIBACTERIAL AND NUTRACEUTICAL PROPERTIES OF THREE DIFFERENT COLOURED SCENTED RICE VARIETIES OF NORTH- EASTERN REGION

The present study was conducted to evaluate the antioxidant, antibacterial and nutraceutical properties of three coloured scented rice varieties grown in North Eastern region. The study for the analysis of Nutraceutical content involved more than five contents to find a significant correlation of the all the rice varieties. Antioxidant activity was measured using hydrogen peroxide and 2, 2-dipheny...

R. Devi, B. Devi, B.G. Unni and M. Garg *

Department of Biotechnology Assam downtown University, Panikhaiti, Guwahati, Assam, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).2968-74

2968-2974

157

67

31.

RELATIVE EXPLORATION OF IN-VITRO ANTI- INFLAMMATORY ACTIVITIES OF DIFFERENT ARTOCARPUS SEED EXTRACTS

The study was undertaken to investigate and compare in vitro anti inflammatory activities of five varieties of hexane and methanol seed extracts each, specifically Artocarpus heterophyllus, Artocarpus integrifolia, Artocarpus hirsitus, Artocarpus inciscus and Artocarpus integer of Artocarpus species belonging to the family Moraceae by means of most prominent membrane stability assay. Results revea...

Nagala Sirisha *, B. Archana, S. Brahmaji and T. Raghava Rao

Department of Biochemistry, College of Science and Technology, Andhra University, Visakhapatnam, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).2975-81

2975-2981

133

53

32.

ASSESSMENT OF PHYTOCHEMICAL AND ANTIOXIDANT POTENTIAL OF UNDERUTILIZED PEAR (PYRUS PYRIFOLIA) AND PLUM (PRUNUS DOMESTICA) FROM INDIGENOUS HIMALAYAN REGION OF HIMACHAL PRADESH

The present investigation revealed the phytochemical constituent, antioxidant potential and correlation between antioxidant activities with total phenol and flavonoid contents of fruit extracts of Pyrus pyrifolia and Prunus domestica from local Himalayan region of Himachal Pradesh, India. The total phenolic content was estimated by using Folin-Ciocalteu reagent method, whereas, flavonoid content w...

M. Singh *, P. K. Chauhan, V. Kumar and J. Kour

School of Bioengineering and Food Technology, Shoolini University, Solan, Himachal Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).2982-87

2982-2987

129

57

33.

IN-VITRO ANALYSIS OF CINNAMOMUM VERUM FOR FORMULATION OF BIO-ACTIVE COSMETIC GEL

Plants have always been traditionally used to address various disorders. Due to their rich phytochemical profile, they have been employed in a gamut of skin care and concomitant treatment of disorders. In this Study, we screened the aqueous (CAE), hydroalcoholic (CHE) and ethanolic (CEE) extract of leaves of Cinnamomum verum for its activities The antioxidant potential of the extracts were determi...

P. Dhawal, K. Satardekar *, S. Hariharan and S. Barve

KET's Scientific Research Center, V.G Vaze College Campus, Mulund, Mumbai, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).2988-95

2988-2995

140

121

34.

BIO-ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF ETHINYL ESTRADIOL WITH ETHINYL ESTRADIOL-D4 AS INTERNAL STANDARD IN HUMAN K2-EDTA PLASMA BY LC-MS/MS

A sensitive method was developed to determine Ethinyl Estradiol in human plasma by liquid chromatography-tandem mass spectrometric (LC–MS/MS). Separation of analyte and the Internal Standard (IS) Ethinyl Estradiol-d4 using SPE followed by LLE in plasma with TBME, was performed on a LC/MS/MS-API-5500 instrument with SB C18 HT (50mm×3.0mm) 1.8 µm columns at a flow rate of 0.300 ml/min with mobil...

S. Udhayavani *, V. Girija Sastry, R. Govinda Rajan, A. Srinivas and J. K. D. Tejaswi

Department of Pharmaceutical Sciences, College of Pharmacy, Andhra University, Visakhapatnam, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).2996-03

2996-3003

136

56

35.

STUDY OF THE ANTIDEPRESSANT AND ANTINOCICEPTIVE ACTIVITY OF ETHANOLIC EXTRACT OF RHIZOMES OF ZINGIBER OFFICINALE IN EXPERIMENTAL ANIMALS

Objective: Ginger (Zingiber officinale Roscoe), a well-known spice plant, has been used traditionally in the treatment of a wide variety of ailments. The main objective of the work is to evaluate the antidepressant and antinociceptive activity of ethanolic extract of Zingiber officinale in Swiss albino mice. Methods: The present study was design to evaluate the antidepressant property of Zingiber ...

Swopna Phukan * and Karishma Adhikari

Department of Pharmacology, Gauhati Medical, College, Guwahati, Assam, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).3004-09

3004-3009

139

60

36.

PHYTOCHEMICAL SCREENING AND EVALUATION OF ANTIFUNGAL ACTIVITY OF GALL EXTRACTS OF QUERCUS INFECTORIA

The objective of the present work is to study the antifungal activity of gall extracts of Quercus infectoria (Q. infectoria) (Family: Fagaceae). The plant commonly known as gall oak, is a small shrub found in Greece, Asia Minor and Iran. The gall of Quercus infectoria macroscopically, is globose with horny appearances on external surface (1-1.5 cm in diameter) giving rough touch, greyish-brown to ...

S. Vanga *, M. Pingili and S. Tharigoppula

Department of Pharmaceutical Chemistry, Vaageswari Institute of Pharmaceutical Sciences, Ramakrishna Colony, Karimnagar, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).3010-13

3010-3013

109

65

37.

SYNTHESIS, CHARACTERIZATION AND IN-VITRO ANTICANCER EVALUATION OF NOVEL BENZO[D]IMIDAZOLE DERIVATIVES

The novel benzimidazole derivatives were synthesized by 2-acetyl benzimidazole consent to react with various substituted aromatic aldehyde (2a–e) to obtain preferred intermediate chalcones (3a–j), these intermediates are undergo the cyclocondensation with guanidine hydrochloride and phenyl hydrazine yielded benzimidazole derivatives (4a–j and 5a–j respectively). The synthesized compounds w...

S. S. Rajendran, G. Geetha *, R. Venkatanarayanan and N. Santhi

Department of Pharmaceutical Chemistry, PSG College of Pharmacy, Peelamedu, Coimabatore, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).3014-24

3014-3024

140

63

38.

A STUDY ON HEPATOPROTECTIVE ACTIVITY OF ETHANOL EXTRACT OF ZANTHOXYLUM ARMATUM DC (MUKTHRUBI) LEAVES IN EXPERIMENTAL ANIMAL

Zanthoxylum armatum is administered as a hepatoprotective agent during indigestion and hepatic related diseases by traditional healers. So, the aim of this study was to investigate the hepatoprotective activity of ethanol extract of Z. armatum (ZAE) in Paracetamol induced hepatotoxicity in albino rats in comparison with the activities of the known and potent hepatoprotective standard drug Silymari...

J. Oinam, I. Raleng, P. Meitankeishangbam, B. R. Kumari, S. Laishram*

Department of Pharmacology, Jawaharlal Nehru Institute of Medical Sciences, Imphal, Manipur, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).3025-29

3025-3029

125

54

39.

IN VITRO ANTICANCER ACTIVITY OF ETHYL ACETATE EXTRACT AND GREEN NANOPARTICLE SYNTHESIZED FROM CURCULIGO ORCHIOIDES GAERTN – AN ENDANGERED MEDICINAL PLANT

The present study aimed at to study the antioxidant and anticancer activity of ethyl acetate extract and nanoparticles synthesized from Curculigo orchioides. The ethyl acetate extract andnanoparticle synthesized from C. orchioides were used in various antioxidant assays such as DPPH, hydroxyl radicals, hydrogen peroxide and nitric oxide radical scavenging activities. The synthesis of silver nanopa...

T. Selvaraj and P. Agastian*

Department of Plant Biology and Biotechnology, Loyola College, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).3030-38

3030-3038

141

85

40.

LANDFILL LEACHATE DEGRADATION USING ZINC OXIDE UNDER DIRECT SUNLIGHT

There has been a significant increase in the generation of MSW (Municipal Solid Waste) in India over the last few decades. The degradation of persistent organic pollutant using advanced oxidation processes with sunlight as energy source have a great advantage at lower costs. Pallikaranai wetland is a freshwater marsh in the city of Chennai, India. Pallikaranai marshland is the only surviving wetla...

Chandran Loganayagi *, Perumal Andal and Ramsathyajayanthi

Department of Chemistry, School of Basic Sciences, Vels University, Pallavarm, Chennai, Kancheepuram District, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).3039-48

3039-3048

110

71

41.

EFFECT OF HIGH LIPID DIET IN SHRINKING THE AMPICILLIN-INDUCED NEUROTOXICITY IN RAT PUPS, INTER-RELATED TO AUTISM ETIOLOGY

Improper diet can affects the brain and can increase the risk for mental disorders and neurodegenerative diseases like autism. Dietary modification can sometime be helpful to children with autism. The present study examined the effects of a high lipid diet on orally administered ampicillin -induced neurotoxic rats and compared with propionic acid models of autism. Forty young male western albino r...

Ramesa Shafi* and Kaushal K. Chandrul

Department of Biochemistry, Shri Venkateshwara University, Gajraula, Amroha, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).3049-56

3049-3056

135

73

42.

EVALUATION OF CRITICAL CONSUMABLES IN CLEANROOM OF ASEPTIC AREA

Sterility is the complete absence of any viable microorganism in a drug product. The Specification of sterility is unchanging and is independent of the kind of manufacturing Process. Sterilisation of the final product in its container closure system or aseptic manufacturing is followed. Under Terminal sterilisation usually it involves filling and sealing product containers under high quality Envir...

G. Sunil Kumar * and M. P. Gowrav

Department of Pharmaceutics (Unit of Quality Assurance), J.S.S College of Pharmacy, Jagadguru Sri Shivarathreeswara University, Sri Shivarathreeshwara Nagar, Mysore, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).3057-68

3057-3068

122

56

43.

SUCCESS AND FAILURE WITH INTRALESIONAL 3% SODIUM TETRADECYL SULFATE SCLEROSING AGENT IN TWO CASES OF INTRAORAL HEMANGIOMA

Vascular malformations are one of the most common lesions of the oral cavity. The lesion may be a congenital malformation observed in neonates or arteriovenous malformation observed in adults. The treatment of these lesions includes surgical excision, cryotherapy, selective embolization and treatment with intralesional sclerosing agents. We present two cases of benign oral vascular lesions treated...

E. B. Kayalvizhi *, N. Megalaa, K. Thirumurugan, R. Kanmani and G. Sitra

Department of Oral Medicine and Radiology, Madha Dental College and Hospital, Kundrathur Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).3069-74

3069-3074

138

81

44.

EVALUATION OF ANTI-DIABETIC ACTIVITY OF CORCHORUS TRILOCULARIS LEAVES IN STREPTOZOTOCIN INDUCED DIABETIC RATS

The leaves of Corchorus trilocularis possesses several bioactivities and is used in traditional medicinal systems. However, its anti-diabetic activity has not been scientifically investigated so far. The present study was carried out to evaluate the anti-diabetic activity of chloroform extract extract of Corchorus trilocularis (family:  Tiliaceae) leaves in Streptozotocin induced diabetic rats. C...

P. K. Gupta*, S. Jain, A. Kaushik and S. Alok

Institute of Professional Studies College of Pharmacy, Gwalior, Madhya Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).3075-80

3075-3080

147

94

45.

DEVELOPMENT AND VALIDATION OF STABILITY INDICATING HPLC METHOD FOR THE DETERMINATION OF LAPATINIB IMPURITIES IN BULK AND FINISHED FORMULATIONS

A simple, sensitive and stability indicating reverse phase high performance liquid chromatography method (RP-HPLC) was developed and validated for the estimation of Lapatinib and its related substances in bulk and finished dosage forms. The newly developed method was assessed using Zorbax Eclipse C18 (3.5 µm, 100 × 4.6 mm) HPLC column with pH- 4.5 ammonium formate buffer and acetonitrile as mobi...

Ramu Ivaturi * , Manikya T. Sastry and S. Satyaveni

Department of Chemistry, Jawaharlal Nehru Technological University, Kakinada, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).3081-91

3081-3091

124

0

46.

ANTIHYPERTENSIVE EFFECT OF THE ALCOHOLIC EXTRACT OF SEEDS OF PHASEOLUS VULGARIS LINN. (FABACEAE) ON HIGH SALT DIET INDUCED HYPERTENSION IN MALE RATS

Aim: To evaluate the antihypertensive effect of ethanolic extract of seeds of Phaseolus vulgaris Linn. (EEPV) on high salt diet induced hypertension in male rats. Methods: Male wistar rats (180-200g) received high salt diet (8% NaCl) and 1% saline water for 6 weeks, then cannulated for dosing of Enalapril, angiotensin converting enzyme inhibitor (0.5 mg/kg, i.v.) in standard group and EEPV (50 and...

T. Jawaid *, M. Kamal and S. Kumar

Department of Pharmacology, College of Medicine, Dar Al Uloom University, Al Mizan St, Al Falah, Riyadh, Kingdom of Saudi Arabia.

DOI: 10.13040/IJPSR.0975-8232.8(7).3092-97

3092-3097

123

64

47.

ANKLE EDEMA FORMATION DURING TREATMENT WITH THE AMLODIPINE IN A TERTIARY CARE HOSPITAL OF NEPAL

Hypertension is one of the major public health challenges worldwide. Amlodipine, a calcium channel blockers (CCBs), is among the first line antihypertensive drugs used commonly. Amlodipine reduces blood pressure by its vasodilatory action and its adverse drug reactions (ADRs) such as ankle edema, headache and flushing are related with its vasodilatory action. This study is conducted to find the in...

A. K. Sah *, R. K. Jha, D. K. Shah and P. Sah

Department of Pharmacology, College of Medical Sciences, Bharatpur, Chitwan, Nepal.

DOI: 10.13040/IJPSR.0975-8232.8(7).3098-01

3098-3101

131

75

48.

EVALUATION OF ANALGESIC AND ANTI-INFLAMMATORY ACTIVITY OF DOREMA AMMONIACUM GUM IN ANIMAL MODEL

Dorema ammoniacum gum (DAG) has been used for different illnesses in Iranian traditional medicine. The main objective of the present study was to evaluate the analgesic and anti-inflammatory activities of aqueous solution of Dorema ammoniacum gum (DAG) in animal model. The anti-inflammatory and analgesic Effects of DAG were examined using carraginane-induced edema test, formalin test and acetic ac...

A. Bakhtiarian, A. Shojaii *, S. Hashemi and V. Nikoui

Department of Medicinal Plants, Research Institute for Islamic and Complementary Medicine and School of Traditional Medicine, Iran University of Medical Sciences, Tehran, Iran.

DOI: 10.13040/IJPSR.0975-8232.8(7).3102-06

3102-3106

122

69

49.

ISOLATION AND MOLECULAR CHARACTERIZATION OF SHIGA TOXIN PRODUCING E. COLI O157:H7 IN RAW MILK USING mPCR

Raw milk may contain pathogenic microorganisms, probably harmful to humans inclusive of Escherichia coli O157:H7 inflicting hemorrhagic colitis and hemolytic-uremic syndrome. Raw milk is believed to be a high risk food as it is highly nutritious and results in growth and multiplication of different microorganisms. E. coli O157:H7 infect humans by different mode of transmission. Present study was p...

B. Tahira, K. Ullah *, A. Samad, S. Ali, S. Nabi, Md. Naeem, H. Hussain and A. Mohammad

Department of Microbiology, University of Balochistan, Quetta, Pakistan.

DOI: 10.13040/IJPSR.0975-8232.8(7).3107-12

3107-3112

137

57

50.

NUTRACEUTICALS: A SLOW TRANSITION FROM PREVENTIVE TO CURATIVE HEALTHCARE AND THE PERCEPTIONS AMONG PHYSICIANS AND PATIENTS – A STUDY OF SOUTH DELHI IN INDIA

Introduction: The health and wellness sector is bracing for a radical change with Information and Communication Technology taking the leading role in research and development, diagnostics, and monitoring. The consumer’s focus is shifting from treatment-based remedies to preventive remedies gradually. Aim: To explore the slow transition from curative to preventive healthcare in the prescribing be...

T. U. Zaman *, H. A. Adetunji and E. F. M. Salih

Department of Health Information Management and Technology, Faculty of Public Health and Health Informatics, Umm Al Qura University, Aziziyah, Makkah, Saudi Arabia.

DOI: 10.13040/IJPSR.0975-8232.8(7).3113-17

3113-3117

108

73

51.

COMPARITIVE EFFECTS OF HORMONAL AND NON HORMONAL CONTRACEPTIVES ON FASTING BLOOD SUGAR LEVELS

The objective of the current study was to differentiate contraceptives for their effects on carbohydrate metabolism. This is a cross sectional design that was conducted in different clinical settings of urban population who belong to low socio economic status by convenience sampling method. Females representing fertile age ranging from 26 to 32 and maintained on different types of hormonal and non...

S. Jamil *, S. Fatima, H. Dilshad, H. Khatoon and N. Jawed

Faculty of Pharmacy 1, Jinnah University for Women, Karachi, Pakistan.

DOI: 10.13040/IJPSR.0975-8232.8(7).3118-21

3118-3121

134

66

52.

ANTIOXIDANT ACTIVITY, DNA DAMAGED PROTECTION AND APOPTOSIS INDUCTION POTENTIAL OF VERNONIA AMYGDALINA LEAF EXTRACTS

The challenges of free radicals and tumour promoting agents are on the increase and this informed investigation of the antioxidant property and anticancer potential of Vernonia amygdalina, a most common medicinal vegetable in Nigeria. The leaf of Vernonia amygdalina was extracted in methanol and partitioned into hexane, ethyl acetate and aqueous layers successively. Activity guided fractionation f...

J. A. O. Olugbuyiro *, D. Odugbesan, S. O. Rotimi and S. L. Uchechukwu

Department of Chemistry, Natural Products Unit, Covenant University, Ota, Nigeria.

DOI: 10.13040/IJPSR.0975-8232.8(7).3122-27

3122-3127

135

57

53.

EVALUATION OF PREDICTORS FOR THE OCCURRENCE OF ENOXAPARIN BRUISING SIDE EFFECT

Enoxaparin is useful in the treatment of unstable angina, but its use is associated with many hematological side effects principally bruising appearance. A prospective comparative study was designed to evaluate the effects of certain predictors on the occurrence of bruising side effect of enoxaparin during the administration of two different subcutaneous (SC) doses (prophylactic vs. therapeutic) o...

Anmar Al-Taie *, Hadeer Akram Abdulrazzaq and Abeer Al-Rasheed

Clinical Pharmacy Department, College of Pharmacy, Al-Mustansiriyah University, Baghdad, Iraq.

DOI: 10.13040/IJPSR.0975-8232.8(7).3128-32

3128-3132

145

65

54.

IN-VITRO DISSOLUTION TESTING FOR THERAPEUTIC EQUIVALENCE OF METRONIDAZOLE IMMEDIATE RELEASE TABLETS AVAILABLE IN KARACHI, PAKISTAN

Metronidazole is a class I drug in biopharmaceutics classification system (BCS) and widely used in Pakistan, various available brands in local markets along with innovator brand to serve a large population. In-vitro dissolution testing can be used as waiver for in-vivo bioequivalence studies of generic brand interchangeability for Class I drugs i.e., highly soluble and highly permeable. The object...

S. Fatima *, S. Jamil, S. Gauhar, M. Maboos and Q. Iftekhar

Faculty of Pharmacy 1, Jinnah University for Women, Karachi, Sindh, Pakistan.

DOI: 10.13040/IJPSR.0975-8232.8(7).3133-37

3133-3137

146

62

55.

THE IMPACT OF PHARMACEUTICAL SERVICES QUALITY ON BUILDING A STRONG RELATIONSHIP BETWEEN PHARMACISTS AND THEIR CUSTOMERS

Background: Pharmacy is an important profession in Jordan whereby it plays a vital role in providing the pharmaceutical services required for the health care of patients and it is an effective factor in the economy and development of the nation. Therefore, it is important to focus on the relationship between pharmacists and their customers through providing high quality pharmaceutical services. Ob...

M. A. Abujarad Alhuwitat * and F. SH. Salem

Pharmacist Researcher, MBA major Marketing, Amman Arab University, Amman, Jordan

DOI: 10.13040/IJPSR.0975-8232.8(7).3138-45

3138-3145

128

66

56.

PREVALENCE OF URINARY TRACT INFECTION IN CHILDREN WITH NEPHROTIC SYNDROME

Introduction: Nephrotic syndrome is the most common chronic glomerular diseases in children. The most common infection in children with nephrotic syndrome is urinary tract infection. The aim of this study was to evaluate the prevalence of urinary tract infection in children with nephrotic syndrome and to prepare and submit an appropriate protocol regarding the necessity and method of UTI examinati...

M. Salarzaei, S. Saravani, M. Heydari, H. Aali, A. Malekzadegan, D. Soofi, E. Rahimi Movaghar, S. Mir and F. Parooei *

Students Research Committee, Students Research Committee, Zabol University of Medical Science, Zabol, Iran.

DOI: 10.13040/IJPSR.0975-8232.8(7).3146-50

3146-3150

148

52

57.

ORAL NANO-EMULSION OF FENUGREEK OIL FOR TREATMENT OF DIABETES

Diabetes mellitus (DM) is one of the principal causes of death in the world. DM causes many diseases with different pathogenesis disturbing glucose, protein and lipid metabolism. The primary characteristic is elevated glucose, blood level, which may be due to deficiency in the secretion of insulin and / act. Fenugreek oil is covered to recover glucose levels, intolerance, and insulin sensitivity a...

Khidir A. M. Hassan* and Md Ali Mujtaba

Pharmaceutics Department, Faculty of Pharmacy, University of Northern Border, Kingdom of Saudi Arabia.

DOI: 10.13040/IJPSR.0975-8232.8(7).3151-54

3151-3154

118

87

58.

ANTIBACTERIAL ACTIVITY OF NIGELLA SATIVA L. SEED OIL IN WATER EMULSION AGAINST DENTAL CARIOGENIC BACTERIA

Our previous study highlighted the antimicrobial activity evaluation of Nigella sativa seed oil extract that was obtained from supercritical fluid extraction using carbon dioxide (SCFE-CO2) on Gram positive pathogenic bacteria. The aim of this study was to formulate oil-in-water (o/w) emulsion of previous N. sativa seed oil extract and to investigate its antimicrobial activity against Streptococcu...

Beatrix T. Gasong, Apriliana W. Hartanti and Raymond R. Tjandrawinata *

Dexa Laboratories of Biomolecular Sciences (DLBS), PT Dexa Medica, Cikarang, West Java, Indonesia.

DOI: 10.13040/IJPSR.0975-8232.8(7).3155-61

3155-3161

121

60

59.

WOUND HEALING ACTIVITY OF TOPICAL LAWSONE GEL ON RAT MODEL

The objective of present work is to study the wound healing effect of topical lawsone gel. Topical lawsone gel was prepared by using natural and synthetic polymers in different ratios. The gel was prepared with Tara gum and HPMC K15M using dispersion method. Optimized gels were characterized for physicochemical evaluations. Optimised formulations (LT3, LT4) were evaluated for spreadability (10.6±...

P. K. Lakshmi *, Narmada Thangellapalli, Amoolya Chennuri, D. Prasanthi and B. Veeresh

Department of Pharmaceutics, G. Pulla Reddy College of Pharmacy, Mehdipatnam, Hyderabad, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).3162-69

3162-3169

101

72

60.

IN VITRO ANTIOXIDANT STUDIES ON COLONIAL ASCIDIANS EUDISTOMA VIRIDE AND DIDEMNUM PSAMMATHODES

Ascidians are rich source of novel bioactive agents as potential source of therapeutic drugs. Evaluation of antioxidant potential of ascidians, Eudistoma viride and Didemnum psammathodes extracts was undertaken. In DPPH radical scavenging assay E. viride II showed 34% to 93% scavenging activity and D. psammathodes II showed 45% to 96% scavenging activity in different ascidian concentrations. In re...

N. Sri Kumaran* and S. Bragadeeswaran

Department of Marine Biotechnology, AMET University, Kanathur, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).3170-79

3170-3179

102

57

61.

INVESTIGATING THE FREE RADICAL SCAVENGING AND ACETYLCHOLINESTERASE INHIBITION ACTIVITIES OF ELLETARIA CARDAMOMUM, PIPER NIGRUM AND SYZYGIUM AROMATICUM

Spices have been used since long to enhance the flavor and aroma of our foods. Besides, they also produce several medicinal effects and are used in treating various clinical ailments. The different phytochemicals present greatly influence the biological activities possessed by plants/spices. The present research work investigates the free radical scavenging and acetylcholinesterase (AchE) inhibiti...

Manasvi Gupta, Chhavi Sharma, Poonam Meena and Manisha Khatri

Department of Biomedical Science, Shaheed Rajguru College of Applied Sciences for Women, University of Delhi, Delhi, India.

DOI: 10.13040/IJPSR.0975-8232.8(7).3180-86

3180-3186

108

67