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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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Volume 15 (2024) - Issue 4, April

Review Articles

 
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1.

THEPESIA POPULNEA FOR THE MANAGEMENT OF DIVERSE DISEASES: AN OVERVIEW

Thespesia populnea Linn., a member of the Malvaceae family also known as Portia tree, a plant commonly found in coastal and tropical regions of India. Its therapeutic properties have been recognized in ayurvedic medicine, which has been validated by modern scientific research. This paper highlights the chemical constituents and pharmacological profile of Thespesia populnea. The plant has shown rem...

Dipti Pal, Smita Suthar, Aman Naskar and Sanmati K. Jain *

Department of Pharmacy, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur, Chhattisgarh, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).990-05

990-1005

288

256

2.

CHRONOPHARMACOLOGICAL ASPECT ON IMPAIRMENT OF LIVER CIRCADIAN CLOCK AND HEPATIC DYSFUNCTION: A REVIEW

Hepatitis B, Diabetes, Alcoholic and Non-alcoholic Fatty Liver Disease, Cholangiocarcinoma, Cholangioleiomyopathies, and other risk factors for hepatic illness are all becoming more harmful nowadays. In animals, the dysfunction of melatonin levels and an unbalanced circadian rhythm can control physiological processes and cellular mechanisms during periods of rest and activity. The Suprachiasmatic ...

Lopamudra Saha, Debarati Kar and Dipanjan Mandal *

Department of Pharmacy, Guru Nanak Institute of Pharmaceutical Science and Technology, 157/F, Nilgunj Road, Sodepur, Kolkata, West Bengal, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1006-14

1006-1014

220

119

3.

MEDICINAL IMPORTANCE OF TRADITIONAL INDIAN HERBAL PLANT OXALIS CORNICULATA: A REVIEW

Oxalis corniculata is a perennial weed which is found in both tropical and temperate climates, it grows in damp and shaded areas throughout the Himalayas and warmer regions of India. This herb, an invasive weed has a number of valuable secondary metabolites. Numerous research has demonstrated the advantages of Oxalis corniculata leaf extract. Its metabolite profile, phytochemical analysis and ther...

M. Kubade and P. Shetti *

Department of Biotechnology, Kaher’s Dr. Prabhakar Kore Basic Science Research Centre, Nehru Nagar, Belagavi, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1015-24

1015-1024

256

113

4.

BACH FLOWER REMEDIES: NATURAL THERAPEUTIC FOR BALANCING EMOTIONS

Bach Flower Remedies were identified by Dr. Edward Bach who was a physician and homoeopath. His discovery and life history for these flower therapy to atone and cure emotions is stated. It affirms that factors like depression, anxiety, stress, anger etc. affects emotions and triggers diseases. The 38 flower remedies emphasize on Bach’s Philosophy of seven principle of causes and its healing stag...

Aditi Patel and Zarna Dedania *

Department of Quality Assurance, Bhagwan Mahavir College of Pharmacy, Bhagwan Mahavir University, BMEF Campus, Near Aakash E-Space, Bharthana, Vesu, Surat, Gujarat, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1025-35

1025-1035

237

94

5.

A COMPREHENSIVE REVIEW ON NUTRITIONAL ASPECTS, CHEMICAL COMPOSITION AND PHARMACOLOGICAL ATTRIBUTES OF BLACK AND WHITE PEPPER

Indian spices and medicinal herbs are well known throughout the world. Both have many different physiological and pharmacological characteristics. The current biomedical research is mostly concentrated on finding chemicals extracted from natural sources that are pharmacologically efficient and have little to no side effects for application in food production and preventative medicine. Pepper (Pipe...

Moumita Saha and Sirshendu Chatterjee *

Department of Biotechnology, Techno India University, West Bengal, EM-4, Salt Lake, Sector- V, Kolkata, West Bengal, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1036-43

1036-1043

214

84

6.

MULTIFACETED APPLICATION OF CURCUMIN IN TRADITIONAL HEALTHCARE SYSTEM

Curcumin, a substance produced from the root of the plant Curcuma longa, has been used for thousands of years in Ayurveda and traditional Chinese medicine to treat a variety of inflammatory disorders. Curcumin, the turmeric key ingredient responsible for this function, was discovered over two centuries ago. Curcumin exerts its effects via altering a number of crucial molecular targets, including t...

Manish Kumar and Shweta Agarwal *

Department of Pharmaceutics, LR Institute of Pharmacy, Solan, Himachal Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1044-52

1044-1052

75

37

7.

MEDICAL DEVICE REGULATIONS AND CURRENT CHALLENGES IN THE GROWTH OF MEDICAL DEVICES IN INDIA: AN OVERVIEW

Medical device, a device or instrument or apparatus or that is used to treat or prevent or diagnose or mitigate or cure the disease or to replace the structure of the body parts mimicking the natural function. The medical device sector started to grow rapidly in the last 8 years. Developed countries like the USA, European Union, and Japan concentrated on this sector to increase their production ca...

Thillai G. E. Govinda Rajan, M. Vignesh *, N. Swathi, N. Swetha, S. Priyadharshini, P. S. Sivaranjani and S. Sophia

Department of Pharmaceutics, Sri Ramachandra Institute of Higher Education and Research, Porur, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1053-58

1053-1058

76

46

8.

ACALYPHA INDICA: PHYTOCHEMICAL CONSTITUENTS, TRADITIONAL USES AND PHARMACOLOGICAL PROPERTIES: A REVIEW

Plants have been the major source of drugs in Ayurveda and other ancient system in world. The Ayurveda, Siddha, Unani, Homeopathy systems have evidenced the use of plants for various disorders. Medicinal constituents from plants playa vital role in traditional as well as western medicine. Acalypha indica L. belongs to family Euphorbiaceae and is a common weed found in Asia, including India, Pakist...

Aishwarya S. Shinde *, Asmita A. Tigote and Supriya D. Ajetrao

Department of Pharmacology, Appasaheb Birnale College of Pharmacy, Sangli, Shivaji University, Kolhapur, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1059-64

1059-1064

71

37

9.

BIBLIOMETRIC ANALYSIS OF LIQUID CRYSTALLINE NANOPARTICLES IN TRANSDERMAL DRUG DELIVERY AND THERAPEUTICS ADVANCES

This systematic review provides a comprehensive overview of recent advancements in liquid crystalline nanoparticles (LCNs) utilized for transdermal drug delivery systems. Recent literature indicates a surge in research emphasizing lipid carriers derived from glyceryl monooleate and monoolein. The inherent nanostructure of LCNs offers superior solubilization capacity for bioactive molecules and con...

Rupali Sharma *, Shekhar Sharma, Arun Mittal, Shabnam Thakur, Preeti Gupta, Anima Pandey and Satish Sardana

Amity Institute of Pharmacy, Amity University Haryana, Manesar, Gurgaon, Haryana, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1065-85

1065-1085

64

36

10.

A SYSTEMIC REVIEW ON THE PATHOGENESIS OF IBD, ALTERATIONS IN GUT MICROBIAL ECOLOGY OBSERVED IN IBD, ROLE OF CYTOKINES (TNF-, INF-, IL-1, IL-6, IL-4, IL-5, IL-10) IN IBD AND RECENT THERAPEUTIC STRATEGIES

Inflammatory bowel disease (IBD) is a chronic inflammatory illness of the gastrointestinal tract that consists of Crohn's disease and ulcerative colitis. The pathogenesis of IBD is multifactorial and involves a complex interplay between genetic, environmental, and immunological factors. A comprehensive literature search was conducted using relevant databases, such as PubMed, Scopus, and Web of Sci...

Hiba Parveen, Tenzin Wangpo, Himanshu Singh, Akhilesh Patel, Shashi Alok, Junaid Tantray and Sanjay Nagdev *

Department of Quality Assurance 6, Shri. Prakashchand Jain College of Pharmacy & Research, Jamner, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1086-98

1086-1098

80

67

Research Articles

 
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11.

CHEMICAL CHARACTERISATION, EVALUATION OF ANTIOXIDANT ACTIVITY AND ACUTE TOXICITY OF POLAR EXTRACTS OF TABERNAEMONTANA CRASSA BENTH (FAMILY APOCYNACEAE)

Tabernaemontana crassa Benth, synonym Tabernaemontana jollyana Pietre ex Stapf, is a Central African pharmacopoeia plant whose stem bark is widely used in traditional medicine. The aim of this study was to evaluate the acute toxicity of aqueous extracts of this species. Preliminary phytochemical tests carried out on the different crude extracts of T. crassa revealed the following chemical groups: ...

Ngaïssona Paul *, Namkona Frédéric Armel, Koane Jean Noël, Etou-Ossibi Arnaud Wilfried, Nkounkou Loumpangou Célestine, Syssa-Magalé Jean-Laurent and Ouamba Jean-Maurille

Laboratory of Architecture, Analysis and Reactivity of Natural Substances, Faculty of Sciences, University of Bangui, BP.908 Bangui.

DOI: 10.13040/IJPSR.0975-8232.15(4).1099-06

1099-1106

208

119

12.

MOLECULAR DOCKING AND MOLECULAR DYNAMIC SIMULATION STUDIES OF CHALCONE DERIVATIVES AS TOPOISOMERASE II INHIBITORS

Cancer is the uncontrolled growth of abnormal cells in the body. It is the second leading cause of death globally, accounting for an estimated 9.6 million deaths in 2018. Topoisomerases are important cellular targets especially in the treatment of human cancers. They are of two types mainly topoisomerase II alpha and beta.  Some of the most powerful anticancer drugs used clinically such as etopos...

Manu Jose * and P. M. Jayalakshmi

Department of Pharmaceutical Chemistry, Nirmala College of Pharmacy, Muvattupuzha, Kerala, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1107-21

1107-1121

202

92

13.

EFFECT OF STRYCHNOS POTATORUM LINN ON REPRODUCTIVE FUNCTION IN FEMALE DIABETIC RATS

Objective: During the reproductive years, diabetes has been associated with menstrual abnormalities, sexual dysfunction and increases infertility rates among females. Strychnos potatorum Linn (S. P. Linn) has been recognized as antidiabetic drug as an Ayurveda medicine. This study was done to estimate whether S. P. Linn can control diabetes and prevent diabetes related complication in the reproduc...

Asish Biswas, Tanmoy Kanti Goswami, Prabir Kumar Ghosh, Santanu Hazra, Himangshu Mahato and Arunava Biswas *

Department of Pharmacology, Maharaja Jitendra Narayan Medical College & Hospital, Cooch Behar, West Bengal, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1121-27

1122-1127

184

77

14.

EVALUATION OF THE NEUROBEHAVIOURAL ACTIVITIES OF CRUDE LEAF EXTRACTS OF SARCOCEPHALUS LATIFOLIUS AND ITS EFFECT ON MICROANATOMY OF TEMPORAL LOBE OF ADULT WISTAR RATS

Sarcocephalus latifolius have a wide range of medicinal applications.  This study evaluated the neurobehavioural activity of crude Leaf extract of Sarcocephalus latifolius on wistar rats and the effect on the histoarchitecture of the temporal lobe. Sixteen adult Wistar rats were divided into four groups of four rats each. Group A served as the negative control and received distilled water, B and ...

Okoronkwo Samuel Okafor *, Anyanwu, Gabriel Emeka, Uchewa, Obinna Onwe, Okoronkwo, Akudo Christain and John E. Abraham

Department of Anatomy, Faculty of Basic Medical Sciences, David Umahi Federal University of Health Sciences, Uburu Ebonyi State, Nigeria.

DOI: 10.13040/IJPSR.0975-8232.15(4).1128-34

1128-1134

208

75

15.

FORMULATION AND EVALUATION OF BI-LAYERED TABLET OF ATENOLOL AND HYDROCHLOROTHIAZIDE

The study focuses on creating and evaluating a specialized bilayer tablet for treating hypertension. It begins with in-depth preformulation analyses of key components like Atenolol, Hydrochlorothiazide, and various excipients. Special emphasis is placed on optimizing the powder blend's flow properties to facilitate tablet compression. A series of tests on resulting tablets (F1 to F8) assess weight...

Aashu Suryawanshi *, Ashok Koshta, Anamika Singh, Sapna Malviya and Anil Kharia

Modern Institute of Pharmaceutical Sciences, Gram: Alwasa, Behind Rewati Range, Sanwer Road, Indore, Madhya Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1135-46

1135-1146

207

99

16.

FORMULATION AND EVALUATION OF EFFERVESCENT FLOATING TABLETS OF TIZANIDINE HYDROCHLORIDE USING COMBINATION OF POLYMERS

The present study was carried out with an objective of formulation and evaluation of effervescent floating tablets of Tizanidine hydrochloride using combination of polymers. The floating tablets were prepared using HPMC and Tara gum as a combination of polymers. The tablet was prepared by direct compression method. The effect of polymer concentration was evaluated for gastroretention and sustained...

Shikha Yadav *, Ashish Rathore, Kirti Malviya, Sapna Malviya and Anil Kharia

Indore and Modern Institute of Pharmaceutical Sciences, Indore, Madhya Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1147-56

1147-1156

58

40

17.

CHEMICAL COMPOSITION, ANTIOXIDANT, ANTIBACTERIAL ACTIVITY OF ISOLATED OIL AND METHANOL EXTRACT OF TRIDAX PROCUMBENS L.

Tridax procumbens L. is an annual herb that has been used in Ayurveda, Unani, and traditional medicine in India to cure various microbial infections, skin diseases, bronchial disorders, and wound healing. The current study aims to investigate the chemical composition, antioxidant, and antibacterial activities of isolated oil (denoted as TPMG oil) from methanol extract using column chromatography. ...

Varsharani V. Ingole and Sushma R. Katade *

Department of Chemistry, PES’s Modern College of Arts, Science and Commerce, Ganeshkhind, Pune, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1157-66

1157-1166

62

40

18.

FORMULATION AND EVALUATION OF FAST DISINTEGRATING TABLET OF LORATADINE BYUSINISABGOL MUCILAGE

Aim and Objective: The main aim of the research work is to formulate and evaluate fast disintegrating tablets of Loratadine by incorporating Ispaghula Mucilage as a Superdisintegrant. Materials and Methods: Tablets were produced utilizing the direct compression technique, incorporating three distinct synthetic superdisintegrants and a natural superdisintegrant (Ispaghula mucilage) at varying conce...

G. Bhuvana Krishna Prasad, M. Pradeep Kumar *, K. Aruna, M. Mahesh and Neelima Satrasala

Department of Pharmaceutics, Vasavi Institute of Pharmaceutical Sciences, Kadapa, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1167-73

1167-1173

66

39

19.

ISOLATION OF BIOSURFACTANT-PRODUCING BACTERIA FROM OIL-SPILLED SOIL AND CHARACTERIZATION OF THEIR SECRETED BIOSURFACTANTSIN PATHOGEN-INHIBITION AND OIL-EMULSIFICATION

Microbial bio-surfactants are surface-active amphiphilic molecules produced by bacteria, yeast and fungi. Biosurfactant-producing bacteria, often recoveredfrom oil-polluted sites, have significant role in microbial enhanced oil recovery (MEOR), environmental sustainability and pharmaceutical applications. The objective of the present study includes isolation, screening and selection of biosurfacta...

Mohammad Zobaer, Ferdausi Ali, Nural Anwar *, Mohammed Sajjad Hossain Bappi, Takia Binte Bakar, Tanim Jabid Hossain, Sajib Khan and ANM Shahriar Zawad

Department of Microbiology, University of Chittagong, Chattogram 4331, Bangladesh.

DOI: 10.13040/IJPSR.0975-8232.15(4).1174-83

1174-1183

126

58

20.

NITISINONE IN HUMAN PLASMA: UPLC-MS/MS ASSAY VALIDATION AND STABILITY STUDIES

A simple, precise, and rapid ultra-performance liquid chromatography coupled with tandem mass spectrometry (UPLC-MS/MS method for determination of nitisinone in 20 µl human plasma was developed and validated. Nitisinone 6C13 was used as an internal standard (IS). Chromatographic analysis was performed on an Atlantis dC18 column (2.1 x 100 mm, 3 µm) using a mobile phase consisting of methanol and...

Syed N. Alvi * and Saleh Al Dgither

Environmental Health Program, Cell Biology Department, King Faisal Specialist Hospital & Research Center, P O Box # 3354, MBC-03, Riyadh 11211, Saudi Arabia.

DOI: 10.13040/IJPSR.0975-8232.15(4).1184-89

1184-1189

59

33

21.

RP-HPLC BIOANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE SIMULTANEOUS ESTIMATION OF METFORMIN AND LEVOTHYROXINE IN HUMAN PLASMA- DRUG INTERACTION STUDIES

A simple, sensitive, robust and specific high performance liquid chromatographic (HPLC) method was developed and validated for the simultaneous determination metformin and levothyroxine in human plasma. In the current study, the analysis was performed on Phenomenex Luna 5µ C18 100A (250 x 4.6mm, 5 micron) column using acetonitrile: methanol: 0.03M phosphate buffer (pH 2- 3.5) 50:10:40 v/v/v as mo...

Jinesh Bahubali Nagavi *, Subhajit Ghosh and Preethi Gotadake Anantharaju

Department of Pharmaceutical Chemistry, Sarada Vilas College of Pharmacy, K.M. Puram, Mysore, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1190-97

1190-1197

60

36

22.

STABILITY STUDY OF NEWLY FORMULATED EMULSION WITH MARKETED FORMULATION

The aim of the article is to formulate and evaluate emulsion also perform comparative study with marketed formulation. Emulsion is a heterogeneous system consisting of at least one immiscible liquid dispersed in another in the form of droplets. Emulsion is prepared with castor oil and liquid paraffin. One marketed formulation was taken for comparison. Identification tests, evaluation tests and sta...

Pratik K. Shinde * and Bharatee P. Chaudhari

YSPM’S, Yashoda Technical Campus, Faculty of Pharmacy, Wadhe, Satara, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1198-02

1198-1202

67

38

23.

FORMULATION AND EVALUATION OF EFFERVESCENT GRANULES PREPARED BY USING MORINGA OLEIFERA (LAM) LEAF EXTRACT

Moringa oleifera leaves, have a high antioxidant content, which is beneficial for overcoming free radicals in the body. The leaves contents have the potential to be developed into a functional drink in the form of effervescent granules. The important aspects influencing the acceptability of granule is the type and ratio of the effervescent agent. In this study, citric acid and sodium bicarbonate w...

S. Amudha *, V. Vijaya Kumar, G. Sharmila and K. Pradeep

Department of Pharmaceutics, School of Pharmacy, Sathyabama Institute of Science and Technology, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1203-08

1203-1208

70

46

24.

ANTIBIOTIC MISUSE: A THREAT TO THE COMMUNITY

Lack of awareness about antibiotics use among healthcare practitioners can be a great threat to the community. There is a need to bring awareness among the healthcare providers and the pharmacists regarding the over the counter (OTC) medications list and indications of OTC medication prescribing and dispensing. Pharmacists are important members of the healthcare team and they play a major role in ...

Maryam Fatima *, Salwa Sahar Azimi and Tarannum Tarannum

Apollo Health City, Hyderabad, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1209-14

1209-1214

68

37

25.

ASSESSMENT OF FATIGUE IN DIALYSIS [PERITONEAL AND HEMODIALYSIS] AND NON- DIALYSIS PATIENTS OF CHRONIC KIDNEY DISEASE

Background: Fatigue is a common symptom in patients with advanced kidney disease, with implications for quality of life and clinical outcome. Fatigue is one of the most frequent complaints of dialysis patients and is associated with impaired health related quality of life (HRQOL). Aim: To monitor and measure the severity of fatigue in dialysis and non-dialysis patients of chronic kidney disease. M...

Kannan Sreevasumathi *, J. Pravallika, A. Himavarsha, B. Harshitha, Ram and K. Tirumala Naik

Krishna Teja Pharmacy College, Tirupati, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1215-22

1215-1222

68

33

26.

FORMULATION AND EVALUATION OF SOLID DISPERSION TABLET CONTAINING TINIDAZOLE

This study focused on the development and evaluation of solid dispersions of Tinidazole, aimed at creating a fast-release tablet formulation. The preparation involved using carriers such as PEG 4000 and HPMC. Solid dispersions were created using both solvent evaporation and fusion methods. The resulting solid dispersions exhibited desirable properties, appearing as fine and free-flowing powders. I...

Aafreen Husain *, Ashok Koshta, Ankur Joshi, Sapna Malviya and Anil Kharia

Modern Institutes of Pharmaceutical Sciences, Indore, Madhya Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1223-37

1223-1237

64

34

27.

AN EFFICIENT METHOD FOR ANTHER AND OVARY CULTURE IN ABELMOSCHUS ESCULENTUS (L.) MOENCH. IN-VITRO

Okra (Abelmoschus esculentus (L.) Moench.) is an important nutrient-rich vegetable crop also known as “lady’s finger”, widely grown in the tropics and sub-tropics mainly for its edible pods and is an alloploid. The haploid technique has been used in plant breeding for the improvements of plants and to develop new varieties in a relatively short time. Hence, we have optimized several factor...

S. B. Pawar, P. S. Sartape and R. R. Taur

Institute of Biosciences and Technology, MGM University, Chh. Sambhajinagar, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1238-44

1238-1244

58

55

28.

POSTOPERATIVE PAIN MANAGEMENT BY FENTANYL VS DEXMEDETOMIDINE AS AN ADJUVANT WITH ROPIVACAINE BY TRANSVERSUS ABDOMINIS PLANE (TAP) BLOCK IN INFRA UMBILICAL SURGERIES UNDER SPINAL ANAESTHESIS: A COMPARATIVE STUDY

Introduction: The analgesia effect of anesthetic drugs namely Ropivacaine, can further be enhanced with adjuvants. For postoperative pain management in infra-umbilical surgeries, Ropivacaine with an adjuvant can be used through a Transversus Abdominis Plane (TAP) block, which is a simple and clinical anatomical landmark procedure, suitable in remote areas without advanced modern technical tools. A...

P. M. Sharma, K. Sudhir Rai, Siddhartha Yadav, Manju Sharma and Ratnesh Kumar *

Department of Orthopaedics, Hind Institute of Medical Sciences, Sitapur, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1245-51

1245-1251

74

44

29.

A PROSPECTIVE COMPARATIVE STUDY OF LETROZOLE AND CLOMIPHENE CITRATE IN OVULATION INDUCTION IN WOMEN HAVING PCOS

Introduction: Clomiphene citrate (CC) is the primary drug of choice for ovulation induction in PCOS but resistance to ovarian stimulation is frequent observation with CC. Letrozole (Let), an Aromatase Inhibitor (AI) induces folliculogenesis by releasing hypothalamo-pituitary axis from tonic inhibitory effect of estrogen. Aim: To compare the rate of folliculogenesis, number of follicle count, ovula...

S. Saha, H. H. Shirazee *, M. Murmu, F. Hassan, A. K. Majhi and S. K. Bhattacharya

Department of Gynecology & Obstetrics, R. G. Kar Medical College & Hospital, Kolkata, West Bengal, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1252-60

1252-1260

58

43

30.

COMPARATIVE STUDY BETWEEN RESULTS OF RETROGRADE INTRAMEDULLARY NAILING (RN) VS LOCKED PLATING (LP) IN TREATMENT OF DISTAL FEMUR FRACTURES: A PROSPECTIVE ANALYSIS

Introduction: Distal femoral fractures are among challenging orthopaedic injury constituting 0.4% of all fractures. Despite recent evaluation in operating techniques and surgical implants, debate continues around the choice of implant for various type of distal femur fractures. Method and Material: In prospective randomized study from 2020 to 2022, analysis of 40 patients was done out of which 20 ...

Devashish Chhutani * and Adit Singh

Apollo Medics Hospital Lucknow, Lucknow, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.15(4).1261-69

1261-1269

66

46