Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 4.45 | 2 | 0.64 |
β1-ADRENERGIC RECEPTOR POLYMORPHISMS AND RISK OF ATRIAL FIBRILLATION AFTER CARDIAC SURGERY IN IRANIAN POPULATION
Postoperative atrial fibrillation (POAF) is a frequent rhythm disturbance after cardiac surgery and is associated with poor cardiovascular outcomes. Beta-blocker therapy is an effective strategy to prevent or decrease the high incidence of POAF and β1-adrenergic receptor (β1AR) polymorphisms that affect the cardiac response to β1AR antagonists. The study objective is to analyze the association ...
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DEVELOPMENT OF NOVEL CARBOHYDRATE BASED COMPOUNDS FOR BETTER ANTIPYRETIC ACTIVITY
Carbohydrate-based therapeutics are extremely potent, and many carbohydrate-based drugs are in the stage of preclinical or clinical trials. There is a growing interest in developing carbohydrate analogues for novel drug discovery as most of the recently used carbohydrate drugs display significant pharmacological activities and low toxicity. Also, the search for an antipyretic drug is a never-endin...
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EVALUATION OF ANTIBACTERIAL ACTIVITY OF PENTABARK KASHAYA AGAINST SELECTED BACTERIAL STRAINS CAUSING WOUND INFECTION: IN-VITRO STUDY
Background: Wound infection occurs when one or more organisms invade the wound. Nosocomial infections are the most common hospital acquired infections responsible for mortality and morbidity. Multidrug resistance against bacterial strains is the most serious emerging situation in worldwide, warranting the search for other alternatives. In this regard Pentabark kashaya was developed which contains ...
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DEVELOPMENT AND VALIDATION OF STABILITY INDICATING UPLC METHOD FOR THE SIMULTANEOUS ESTIMATION OF NETUPITANT AND PALONOSETRON IN CAPSULE
A simple, accurate, and precise stability-indicating method was developed for the simultaneous estimation of the Netupitant (NTPT) and Palonosetron (PLSN) in a capsule by UPLC. Chromatographic elution was processed through an HSS C18 (100 × 2.1 mm, 1.8m) reverse phase column, and the mobile phase composition of 0.01N KH2PO4 buffer (4.0 pH) and acetonitrile in the ratio of 55:45 was pumped through...
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DEVELOPMENT OF STABILITY-INDICATING UPLC METHOD FOR THE SIMULTANEOUS DETERMINATION OF TIPIRACIL ANDTRIFLURIDINE IN FORMULATION
Aim of the present research work was to develop a sensitive, precise, and robust stability-indicating UPLC method for the simultaneous estimation of tipiracil and trifluridine in formulations. The chromatographic separation of a mixture of tipiracil and trifluridine was attained in isocratic method utilizing a mobile phase of 0.1% orthophosphoric acid: acetonitrile in the proportion of 50:50% v/v ...
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ANTILITHIATIC ACTIVITY OF LEAF EXTRACT OF CITRUS MEDICA ON SODIUM OXALATE UROLITHIAIS–IN-VITRO AND IN-VIVO EVALUATION
Urolithiasis is a common urological disorder responsible for serious human affliction and cost to society with a high recurrence rate. The aim of the present study was to systematically evaluate the leaf extract of Citrus medica using suitable in-vitro and in-vivo models to provide scientific evidence for its antilithiatic activity. Cystone has been suggested to be beneficial in urolithiasis, as i...
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ISOLATION, IDENTIFICATION AND SCREENING FOR BIOACTIVE COMPOUNDS WITH ANTIMICROBIAL ACTIVITIES FROM SUB-AERIAL CYANOBACTERIA OF EASTERN REGION, ODISHA
Background and Objectives: Cyanobacteria are rich in various bioactive compounds. This study aims to screen the antimicrobial activity of sub-aerial Cyanobacteria isolated from sub-aerial habitats (Old monuments and building facades). Materials and Methods: Crude aqueous and organic extracts were screened for phytochemical constituents and tested for their antimicrobial efficacy against human path...
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DESIGN, SYNTHESIS AND IN-VITRO ANTIMICROBIAL EVALUATION OF MANNICH BASE METAL COMPLEXES
Succinimide and its derivatives are important substitutes of many medicinal compounds in the pharmaceutical field. One of the essential objectives in heterocyclic and medicinal chemistry is the synthesis of molecules having importance as therapeutic agents. Heterocyclic compounds and their derivatives contain an imide ring that can easily cross biological membranes in-vivo. Mannich reactions are o...
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ASSESSING PHARMACOTHERAPEUTIC MANAGEMENT OF ANEMIA IN VARIOUS STAGES OF CHRONIC KIDNEY DISEASE AND POST RENAL TRANSPLANT PATIENTS
Introduction: Anemia in CKD occurs when the kidneys are damaged or diseased. They cannot make enough EPO, which stimulates the bone marrow to produce RBC. It is associated with increased cardiovascular diseases, hospitalization, reduced quality of life, cognitive impairment, and mortality. Materials and Methods: A prospective observational study was conducted on CKD patients. Demographic details, ...
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ANTIALZHEIMER ACTIVITY OF METHANOLIC EXTRACT OF BUCHNANIA LANZAN LEAVES BY USING BEHAVIOUR MODELS ON ALBINO WISTAR RAT
Objective: The key objective of the study is to evaluate the Anti-Alzheimer activity of methanolic extracts of buchnania Lanzan leaves by Aluminum Chloride induced Alzheimer's. Buchanania lanzan Spreng a well-known forest plant of the family Anacardiaceae. It is reported to have numerous uses in the indigenous system of medicine in India. Material and Methods: Albino Wistar rats were administered ...
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