Posted by admin on Jul 31, 2015 in |
The oil polluted soil has many hydrocarbons which can be degraded by microbes. These oil degrading microbes were isolated from the oil contaminated soil through plate and dilution technique. The oil contaminated soils were collected from the oil spilled places of Vaniyambadi and Ambur areas of Vellore District, Tamil nadu, India. Through the biochemical tests, the isolated bacterial strains were identified as Pseudomonas aeruginosa and Bacillus subtilis, the strains were further confirmed by starch hydrolysis test and by growing on cetrimide agar. It is screened for the biosurfactant production through drop collapsing test and Emulsification Index (E24) using diesel, petrol, kerosene and tween 20. Biosurfactants are amphiphilic compounds which reduce surface and interfacial tension. Here, Pseudomonas aeruginosa had shown higher biosurfactant activity, when compared to Bacillus...
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Posted by admin on Jul 31, 2015 in |
Four simple, rapid, inexpensive, precise and accurate UV spectrophotometric methods have been developed for simultaneous estimation of Aspirin (ASP) and Lansoprazole (LANSO). Method A was Simultaneous equation method (Vierodt’s method) which applies measurement of absorptivities at two wavelengths, 276.00 nm, (λmax of Aspirin) and 284.00 nm, (λmax of Lansoprazole) in zero order spectra. The concentrations were calculated from the derived equations. Method B was based on zero crossing first Derivative (D1) spectrophotometry where Aspirin showed zero crossing point at 303nm and Lansoprazole showed zero crossing point at 244.5nm.Method C was Dual wavelength technique, in which absorbance difference between two points on the mixture was measured where difference for one drug is zero and amplitude of other drug was directly proportional to the concentration. Analytical wavelengths for Aspirin were 262nm and 295.7nm; while for Lansoprazole 270nm and 282.5nm were selected. Method D was based on Multicomponent mode technique, in which sampling wavelengths selected were 276 and 284 nm. Linearity for Aspirin was between 26-130 µg/mL and Lansoprazole was 4-20 µg/mL. ...
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Posted by admin on Jul 31, 2015 in |
The effect of aqueous leaf extract of Tridax procumbens on blood coagulation was investigated in order to verify the claim that the said extract can be used to manage bleeding. This was done by examining the effect of the extract on bleeding time, the effect of graded amounts of the extract on clotting time as well as the effect of the heat-treated extract on bleeding time. These were performed using the Duke method, the Lee and white method and an adaptation of the Duke method to the heated extract respectively. In the bleeding time experiment, the mean bleeding time without adding the extract (control) was found to be 2.49 + 0.02 minutes and the mean bleeding time upon addition of the extract was 1.40 + 0.16 minutes thus achieving a 57% decrease in normal bleeding time. When graded amounts of the extract was used for the clotting time experiment and the result analysed by a correlation analysis, the correlation coefficient (r) was -0.99, indicating the existence of an almost...
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Posted by admin on Jul 31, 2015 in |
Treatment ofcancer painis mainly based on the use of opioidanalgesics.This study includes opioids commonly used in Polish clinical practice, such as: dihydrocodeine, tramadol, buprenorphine, morphine, fentanyl, oxycodone and methadone. The purpose of our research is performing a quality assessment of the available clinical trials concerning opioids efficacy and an evaluation of the cause of the limited quantity of systematic reviews in form of meta-analysis. The quality of methodology used in included trials was assessed by Jadad scale. The following databases was searched: Medline (PubMed), Cochrane Library and websites of agencies included in INAHTA (The International Network of Agencies for Health Technology Assessment in Heath). A wide variety of drug dose, dosage forms, routs of administration and pain measuring scales resulted an impossibility of performing a meta-analysis comparing opioids in terms of their effectiveness. Collected studies were assessed for analgesic effect and side effects of opioids therapeutic use, refer to other drugs and depending on doses, frequency of administration, dosage forms (modified/immediate release). The analysis of safety was performed by...
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Posted by admin on Jul 31, 2015 in |
The mouth of human body provides non-shedding surfaces (teeth) for natural microbial colonization. This can result in the accumulation of large masses of bacteria and their products at stagnant sites. Dental plaque, Periodontitis and gingivitis are some of this type of conditions, which can develop due to microbial accumulation on teeth and Infections of throat leading to tonsillitis, pharyngitis, laryngitis, sour throat etc. Chlorhexidine is widely used antimicrobial drug in the treatment of dental plaque and gingivitis and Flurbiprofen is used as anti-inflammatory drug to reduce pain and inflammation. Lozenges are designed to deliver medications directly to the mucus membranes of the mouth and oropharengial cavity by dissolving slowly when placed between the tongue and gums. Lozenges provide maximum amount of local action thus Chlorhexidine and Flurbiprofen are formulated as lozenges to provide local antiseptic and anti-inflammatory action. The candy based lozenges were prepared by heat and congealing method by sugar as lozenge base, HPC, HPMC as polymers, citric acid artificial flavours and colours and other essential excipients. Some...
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