Posted by admin on Sep 30, 2026 in |
Cutaneous warts are common benign proliferative lesions caused by human papillomavirus and remain a therapeutic challenge because of recurrence, cost, and limited accessibility of some conventional treatments. This study evaluated the phytochemical profile, preliminary anti-inflammatory activity, and feasibility of green synthesis of magnesium oxide nanoparticles using hydroethanolic leaf extract of Ficus sycomorus. The extract was subjected to qualitative phytochemical screening, total phenolic content estimation, in-vitro anti-inflammatory assessment using the egg albumin denaturation assay, and preliminary nanoparticle biosynthesis and characterization. Phytochemical screening indicated the presence of alkaloids, flavonoids, tannins, saponins, glycosides, and phenolic compounds, while total phenolic content was estimated at 2.64 mg TAE/g extract. In the egg albumin denaturation assay, the crude extract exhibited concentration-dependent inhibition of protein denaturation, increasing from 26% at 50 µg/mL to 80% at 1000 µg/mL, compared with 35–83% for diclofenac. Green synthesis mediated by Ficus sycomorus extract produced approximately 387.52 mg of magnesium-containing precipitate. FTIR analysis suggested the involvement of plant phytochemicals in particle formation or stabilization, while UV–Vis spectroscopy showed an absorption peak...
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Posted by admin on Sep 30, 2026 in |
Introduction: Zanthoxylum humile, a medicinal plant belonging to the Rutaceae family, has been used for many years in traditional medicine to treat various illnesses. Zanthoxylum plants have been used to treat infections caused by parasites (malaria, leishmaniasis, trypanosomiasis, and other parasitic diseases), as well as sickle cell disease, tumors, and bacterial, fungal, and viral infections. However, there is very little scientific research on the ethnomedical claims around Z. humile. The present study aims to explore the phytoconstituents of the hydroethanolic bark extract, screen for antioxidant activity, and determine the plant’s safety. Methods: Zanthoxylum humile bark was subjected to maceration using hydroethanolic solvent to obtain an extract. Phytochemical screening was performed using gas chromatography–mass spectrometry (GC–MS) to identify bioactive compounds. The antioxidant activity was evaluated using the DPPH assay. Acute oral toxicity was evaluated in accordance with the OECD 425 guideline to determine the safety profile of the extract. Results: GC–MS analysis revealed multiple bioactive phytochemicals, including 2-Methoxy-4-vinylphenol, resorcinol, and copaene, supporting the therapeutic relevance of Zanthoxylum humile. The extract...
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Posted by admin on Sep 30, 2026 in |
Bronchopneumonia is a major cause of morbidity and mortality among children under 5 years of age. Recurrent respiratory infections, significantly affect a child’s quality of life. Although bronchopneumonia has no direct equivalent in Ayurveda, its clinical manifestations like Kasa (cough), Peenasa (rhinitis), Nishteevana (expectoration), Ghurghurakam (wheezing), and Shwasakrichrata (difficulty in breathing) resemble the features described in Tamaka Shwasa. This case report describes the Ayurveda management of recurrent respiratory illness and Bronchopneumonia in pediatric patient. A 1.5-year-old male child presented with recurrent episodes of cough with expectoration, fever, cold, breathing difficulty, and reduced appetite. The child had experienced recurrent respiratory infections since infancy and had been hospitalized for6times for similar complaints. He was previously diagnosed with Influenza B-associated Bronchopneumonia with wheeze based on clinical examination, laboratory investigations, and radiological findings. Management included Ayurveda treatments which aided in improving airway patency. The patient was managed with Ayurveda therapies, including Uro Abhyanga (Localized massage) with Karpooradi Taila followed by Nadi Sweda (fomentation), along with internal medications comprising Pushkaramulasava, Bhringarajasava, Indukantha Kashaya, and...
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Posted by admin on Sep 30, 2026 in |
Pharmacognostic evaluation becomes a simple and reliable method for the authentication of crude herbal drugs, once the morphological characters are lost during processing. This study presents a comprehensive pharmacognostic, physicochemical, and elemental characterization of the root bark of two ethnomedicinally important but underexplored trees- Pajanelia longifolia and Radermachera xylocarpa of Bignoniaceae family. The roots of both species share some common histological characters like stone cells and calcium oxalate crystals, but differ in odour, cork thickness, and crystal size. Minor differences in ash values indicate variation in inorganic content. For the first time, this study reports the mineral and heavy metal elemental profiles of the root bark of P. longifolia and R. xylocarpa. Calcium was identified as the predominant mineral in P. longifolia (268.54 mg Kg⁻¹) and R. xylocarpa (328.43 mg Kg⁻¹), followed by magnesium, highlighting their potential nutritional and therapeutic significance. Major toxic heavy metals such as Al, Ni, Pb, Hg and Co were found to be below detectable levels in both species, while copper was detected only in...
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Posted by admin on Sep 30, 2026 in |
Background: Antimicrobial resistance (AMR) is largely caused by the irrational and inappropriate use of antibiotics. To encourage sensible antibiotic prescription and enhance antimicrobial stewardship, the WHO established the AWaRe (Access, Watch, Reserve) categorization and also\ to uncover irrational prescribing practices. Objectives: To assess antibiotic prescribing patterns and compliance with WHO AWaRe standards in several tertiary care hospital departments. Material & Methods: A cross-sectional observational study was conducted with in-patients admitted to the medical, dermatological, and psychiatric departments of the ‘Assam Medical College and Hospital in Dibrugarh’. Using purposive sampling, 230 prescriptions that contained at least one antibiotic. Case record form was used to document demographic information, diagnosis, recommended antibiotics, mode of administration, length of therapy, and generic prescriptions. Antibiotics were categorized using the WHO AWaRe classification, and Microsoft Excel’s descriptive statistics were used to examine prescription indicators. Results: Antibiotics were given more frequently from the Watch group (56%) compared to the Access group (36%). Ceftriaxone (36.54%) as most commonly prescribed and other broad-spectrum antibiotics accounted for the majority of...
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