Posted by admin on May 30, 2015 in |
The Turmeric (Curcuma Longa.L) plant, a perennial herb belonging to the ginger family is cultivated extensively in South East Asian countries. The polyphenols Curcumin, De methoxy curcumin and Bisdemethoxy curcumin collectively known as curcuminoids ,which aid in the treatment of degenerative diseases like cancer, alzheimer’s, cardio vascular diseases, arthritis, diabetes and immune deficiencies .Curcuminoids are generally present in the rhizome in the ratio Curcumin : DMC : BDMC 55-60% : 19 -21 % :20–24% respectively. When the rhizhome is extracted and the curcuminoids isolated from the extract,there is a composition change from what is naturally found in the rhizhome. The present study gives a comparative data of bio-absorption of two turmeric formulations containing curcuminoids in a varied composition compared to regular turmeric extract. Regular Turmeric extract with 96.5% curcuminoids and two different formulation containing 7.8% curcuminoids and 51% curcuminoids were orally administered to adult albino rats which were divided into 10 groups based on different doses of test item (50 mg/kg, 150mg/kg, 300mg/kg).The absorption of curcuminoids was studied by...
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Posted by admin on May 30, 2015 in |
Nicotine and atorvastatin have indirect effects on reproductive function. So this study focused on changes in testosterone biosynthesis in rats co administered nicotine and atorvastatin. Rats were divided into 4 groups.(1) Control, (2) Atorvastatin (10 mg/Kg b.wt), (3) Nicotine (0.6 mg/Kg b.wt)and (4) Atorvastatin (10 mg/Kg b.wt) + nicotine (0.6 mg/Kg b.wt). After sixty days of treatment testicular cholesterol level, serum testosterone level, activity of HMG CoA reductase in the liver, activities and expressions of testicular steroidogenic enzymes; 3β-hydroxysteroid dehydrogenase (3β-HSD) and 17β-hydroxysteroid dehydrogenase (17β-HSD)and peroxidation products were assayed. Nicotine administration caused hypercholesterolemia, decreased expression of steroidogenic enzymes and testosterone levels. Administration of atorvastatin reduced cholesterol levels, decreased the expression and activity of steroidogenic enzymes and testosterone levels. Co-administration of nicotine and atorvastatin enhanced the testosterone level in comparison with nicotine administration. Enhanced biosynthesis of testosterone in coadministered group may be due to increased activities and expressions of 3β-HSD and 17β-HSD and enhanced expression of StAR protein indicating enhanced transportation of cholesterol. Reduction in oxidative stress was also a...
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Posted by admin on May 30, 2015 in |
During the recent times, the whole world is conscious about the health hazards and toxicity associated with indiscriminate use of synthetic drugs. There is extensive surge of drugs which are safer and having fewer side effects. So there is a growing interest in natural remedies for the management of different ailments. Ayurveda describes different remedies prepared by using maximum percentage of therapeutically potent herbal ingredients. Dandruff is a common scalp disorder that even affects almost half of the population at the pre-pubertal age and of any gender or ethnicity. Description of lepa (preparation used for external application) is available in classical texts in the name of Amrabeejadilepa. Ingredients used for the preparation of this lepa are, Amarbeejamajja (seed kernel of Mangifera indica) and Haritakiphala majja (fruit pulp of Terminaliachubela). Lepa is applied along with milk over scalp 2 in severe dandruff. This promulgation has good anti-microbial, anti-oxidant and anti-inflammatory activity. The present work deals with the development of the amrabeejadi Anti-dandruff cream from amrabeejadilepa (Ayurvedic preparation). Amrabeejadi antidandruff cream...
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Posted by admin on May 30, 2015 in |
Many countries in Africa, Asia and Latin America use traditional medicine (TM) to meet some of their primary health care needs. In Ethiopia, Traditional Medicine (TM) is a part of the national heritage. Also Ethiopia is the home of many nationalities and remarkably diverse flora, including numerous endemic species that are utilized in the different traditional medical practices. Beyond the convenience, traditional home remedies have found favour with a public that wants to take a more holistic approach to its ailments. This study sought to assess the traditional home remedy usage among people in Harar, Ethiopia. The present survey covered the people residing in Kebele 6, Jugal, Harar, Ethiopia. A structured interview questionnaire based on traditional home remedy usage was distributed and face-to-face interviews were conducted. Collected data were tabulated. Among the 338 (100%) respondents, 150 (44%) were males and 188 (56%) were females. 63 (19%) respondents were between the age group of 20 – 25 years, 41 (12%) were between 26 – 30 years, 66 (19%) were between...
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Posted by admin on May 30, 2015 in |
The aim of this study was to determine the anti-microbial and anti-adhesive properties of a Lactobacillus and Bacillus, against several micro-organisms, including Gram-positive and Gram-negative bacteria. Biofilm producing micro- organisms were isolated from different samples. The isolated micro-organism were characterized and identified. The anti-microbial and anti-adhesive activities were determined. The bacteroicin production was quantified and was observed. The maximum bacteroicin production was observed among various isolated micoorganisms. The bacteroicin produced by the Lactobacilli and Bacilli showed antimicrobial activity against pathogenic micro-organisms (including Pseudomonas, Escherichia col, Staphylococcus, Aspergillus and Salmonella typhi), the minimum inhibitory concentration (MIC) were achieved for bacteroicins the most. The antagonistic characteristics of bacteriocin were studied by agar well diffusion method. Furthermore, the micro- organism showed anti-adhesive activity against most of the micro-organisms evaluated. Biofilm production was observed and quantified among various biofilm producing isolated micro-...
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