Posted by admin on Jan 31, 2015 in |
Methanolic extracts of leaf, bark, stem and root of D. paniculata were screened for phytochemicals and antibacterial activity against ten different pathogens. Various phytochemicals such as terpenoids, flavonoids, coumarins, saponins and tannins were found to be present. Leaf and bark extract exhibited maximum antibacterial activity against S. aureus, P. vulgaris and E. coli with MIC value of 2.5 mgmL-1. Significant antibacterial activity was shown by all extracts with MIC ranging from 10 mgmL-1 to 2.5 mgmL-1. Further isolation and characterization of phytochemicals could result in development of drugs against tested...
Read More
Posted by admin on Jan 31, 2015 in |
Objective: To evaluate the pharmacognostic characters of Madhuca indica J.F. Gmel leaf and stem an important traditional medicinal plant. Method: In the present investigation, pharmacognostic parameters like macroscopic and microscopic and powder characters of leaf and stem were studied. Preliminary phytochemical and physiochemical analyses were done by using reported methods. Fluorescent behavior of the leaf and stem powder were also tested. Results: The macroscopic study showed that the leaf was simple and ovate with sinuate margin, acuminate at apex, decurrent at base and surface glabrous and venation was pinnate. The microscopic study of leaf revealed the presence of dorsiventral type of cellular arrangement, unicellular trichomes, prismatic crystals and anomocytic stomata; while the microscopic study of stem revealed the presence of vascular bundles in zig zag form, large central collenchymatous pith. Pith cells were polygonal in shape with minor angular thickenings. Physiochemical analysis of leaf showed total ash, water soluble ash and acid insoluble ash as 4.6, 0.83 and 0.5 %w/w respectively while in stem it was 5.37, 1.5 and...
Read More
Posted by admin on Jan 31, 2015 in |
The compound 3-chloro-2-hydrazine quinoxaline was condensed with 2-furaldehyde to derive a Schiff base 2-furaldehyde-2-(3-chloro-2-quinoxalinyl) hydrazone (FCCQH).The ligand and also its complexes with VO (IV), Cr (III), Mn (II), Fe (III), Co (II), Ni (II), Zn (II), and Pd (II) have been synthesized and characterized by elemental analysis, magnetic studies, thermal analysis, infrared spectra, UV-visible spectroscopy and Electron Spin Resonance data. The ligand 2-furaldehyde-2-(3-chloro-2-quinoxalinyl) hydrazone [FCCQH] acts as a neutral, bidentate one towards VO(IV), Zn(II), and Pd(II) coordinating through free C=N nitrogen and oxygen of furan ring and as tridentate one towards Cr(III), Mn(II), Fe(III), Co(II), and Ni(II) complexes coordinating additionally through nitrogen of quinoxaline ring C=N. The complexes have been screened for antibacterial activity towards staphylococcus aureus (gram +ve), Escherichia coli (gram -ve) bacteria, antifungal activity towards fusarium oxysporum and anticancer activities of the compounds were evaluated by MTT assay on HeLa (cervical cancer) cell lines. While the antimicrobial activity profiles of the complexes are, by and large quite encouraging, the anticancer activity exhibited by Ni (II) and Pd...
Read More
Posted by admin on Jan 31, 2015 in |
Indian medicinal plants traditionally used for the treatment of viral infections with high fever, arthritis, inflammation were investigated for their in vitro antiviral activity against the Asian and East Central South African lineage of Chikungunya virus. In vitro cytotoxic assay of aqueous, aqueous ethanolic and ethanolic extracts of Alpinia Galanga (L) Willd., Alpinia Officinarum Hance., Andrographis paniculata Wall. ex. Nees , Melia azedarach L., and Azadirachta indica A. Juss were assessed for the determination of maximal nontoxic concentration in Vero cell lines. Antiviral activity of aqueous, aqueous ethanolic and ethanolic extracts of plants were determined by the inhibition of virus induced cytopathic assay to both lineages of Chikungunya virus aqueous ethanolic and ethanolic extracts of Melia azedarach L. were found to be effective and inhibited the growth of Chikungunya virus. Asian strain of Chikungunya virus was found to be more susceptible at lower concentrations of the extracts tested than the ECSA...
Read More
Posted by admin on Jan 31, 2015 in |
Bryophytes possess a pool of bioactive compounds with pharmacological activity. These plants have widely been used as medicinal plants since ancient times and are not infected by bacteria and fungi as they use chemical weapons in the form of secondary metabolites. In order to evaluate the antifungal activity of aqueous crude extract of Bryum cellulare (a moss) against the test fungi Curvularia lunata the causal organism of leaf spot of wheat and Drechslera maydis the causal organism of leaf blight of Zea mays was determined using pour plate method. The results revealed that the colony diameter and fresh weight of test organism under the effect of different concentrations was found to be maximum in lower concentrations and minimum in higher concentrations of Bryum cellulare. A phyotochemical screening of the extracts was also carried out to determine the antifungal substances. The results showed that the extract posses good antifungal activity but to varying...
Read More
