Posted by admin on Nov 30, 2023 in |
Sarcostemma acidum Voigt is a xerophytic plant of the family Apocynaceae. Plant is locally known as Somlata. It is a traditional medicinal plant used to prepare Somras. The plant is mainly found in Bihar, West Bengal, Odisha and South India. It is mostly grown in dry rocky places. S. acidum is a shrub, more branched but no leaves. The stems are jointed with each other. These are green, cylindrical having 2 to 4 meter in length and 0.5 cm. to 1 cm. in diameter. The leaves are present opposite but are reduced to scales. So, the plant is leafless in nature. The flowers are actinomorphic, light yellowish white in nature. The roots are branched and each root contain 3 to 5 sub-root branches. The plant extract of S. acidum contains carbohydrates, glycosides, alkaloids, tannins, flavonoids, proteins, steroids, triterpenoids, and fixed oils. Ethnomedicinally the S. acidum was used in otitis, dog bite, snake bite, rabies, emesis, arthritis and leprosy. The juice of this plant having some medicinal value, so used...
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Posted by admin on Nov 30, 2023 in |
Diabetes mellitus has become a global concern with 422 million people affected due to this disease. As the oral hypoglycaemic drugs available in the market have their own set of side effects which can be one of the primary factors towards non-adherence of these medicines among patients, we must explore some natural alternatives in order to deal with this disease in an efficient manner. In such scenario, exploring some intelligent solutions like functional foods can be very helpful as they have the goodness of natural ingredients. The present study focuses on the development of functional food rich in millets, camel milk powder and apple pomace powder. Functional snack bar developed with antioxidant-rich millet mixture (Ragi: Bajra: Kodo: Kutki = 1:1:1:1), insulin-rich camel milk powder and fiber-rich apple pomace powder might have the potential to treat diabetes. Animal studies can be planned in the future in order to validate the product. Moreover, future course of action can comprise of moving into the direction of molecular and cell biology wherein cell...
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Posted by admin on Nov 30, 2023 in |
The present study is aimed to compare the in-vitro antibacterial and antioxidant activities of Aralia cordata Thunberg and Kalopanax septemlobus (Thunb.) Koidzumi (Araliaceae). The antibacterial activity of the two plants was evaluated disc diffusion and minimal inhibition concentration (MIC) method against two Gram-positive bacteria and two Gram-negative bacteria. The tested ether and ethyl acetate fraction of ethanol extract from the two species showed weak antibacterial activity against the tested Gram-positive and Gram-negative bacteria. The ether fraction of the two species exhibited relatively higher antibacterial activity against the tested bacteria as compared to the ethyl acetate fraction. The 1, 1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) free radical scavenging assay was applied for antioxidant activity. Results showed that the DPPH activity (IC50) of ethanol extracts of the two species ranged from 0.05 ± 0.01 to 0.28 ± 0.07 mg/g and the corresponding values for the ABTS activity (IC50) of ethanol extracts of two species ranged from 0.25 ± 0.01 to 1.80 ± 0.23mg/g. The antioxidant activity of ethanol extracts was higher...
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Posted by admin on Nov 30, 2023 in |
The present study is reported the antioxidant activity of oxazole derivatives. Oxazole are five-member heterocyclic ring containing nitrogen and oxygen as a hetero atom. Due to binding with a wide spectrum of receptors and enzymes easily in biological systems through various non-covalent interactions, oxazole-based molecules are becoming a kind of significant heterocyclic nucleus, which have received attention from researchers globally, leading them to synthesize diverse oxazole derivatives. Oxazole have been reported to possess diverse biological activities like antimicrobial, antiviral, anti-inflammatory and anticancer activity. In this research work some heterocyclic like 4-(substituted benzylidene)-2-(pyrazin-2-yl) oxazol-5(4H)-one with potent derivatives for 100 ug/ml are 4-(4-methylbenzylidene)-2-(pyrazin-2-yl) oxazol-5(4H)-one (PA-7), 4-(3-bromo-4-hydroxy-5 methoxybenzylidene) -2-(pyrazin-2-yl)oxazol-5(4H)-one (PA-13) and are 4-(5-Oxo)-2- (pyrazin-2-yl) 4(5H)-ylidene) methyl) benzonitrile (PA-15) and for 200 ug/ml 4-(4-fluoro benzylidene)-2-(pyrazin-2-yl) oxazol-5(4H)-one (PA-4), 4-(4-hydroxy-3-methoxy benzylidene)-2- (pyrazin-2-yl) oxazol-5 (4H)-one (PA-8) and 4-(3-bromo-4-hydroxy-5 methoxybenzylidene) -2-(pyrazin-2-yl) oxazol-5(4H)-one (PA-13) shows promising anti-oxidant activities. The method mainly used as hydrogen peroxide radical scavenging activity. Antioxidant scavenging effect of synthesized derivatives also compared with standard Ascorbic...
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Posted by admin on Nov 30, 2023 in |
The current study aims to develop and evaluate herbal mouthwash and ascertain its effectiveness against microbes. Conventionally herbal mouthwashes are used as a disinfectant to lessen the presence of microbes in the oral cavity. Herbal mouthwashes act as a preventative agent for bleeding gums, decoloring teeth, and killing off bad breath germs. The herbal mouthwashes also have inherent benefits of plaque control and inflammation. The formulated mouthwash was prepared using herbs and the extract was extracted by hot water extraction method. Additional analysis of the Phyto ingredients was done where the flavonoid content and phenolic content was estimated as 41.71µg/ml and 76.25µg/ml, respectively and the in-vitro antibacterial assay was performed against Streptococcus mutans and Streptococcus salivarius and the zone of inhibition was calculated as 18mm and 22 mm at the highest concentration. The results indicated that the mouthwash exhibits effective antibacterial qualities. These solutions can be used for various things, including reducing the growth of germs in the oral cavity and for their analgesic, anti-inflammatory, or antifungal...
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