Posted by admin on Sep 30, 2023 in |
India is the home to the familiar plant Cleistanthus collinus (Roxb.) Benth. ex Hook. F (Euphorbiaceae) has great ethnomedicinal and therapeutic applications. The present study was designed to assess the phytochemical profile and investigate the antifungal effectiveness of leaf, bark and fruit extracts by using the agar well diffusion method. All crude extracts from leaf, bark, fruit and fractions derived also demonstrated significant antifungal activity (20-80%), but the methanol extracts showed a remarkable antifungal spectrum; as a result, GC-MS analysis was performed on it. From this GC-MS analysis, 14 chemicals, including alkanes, glycosides, phenols, flavonoids and steroids were identified, while leaf methanol extract has high phytochemical diversity with 9 compounds than bark with 6 compounds and fruit with 5 compounds. 1, 2, 3-Benzenetriol, 3-O-Methyl-d-glucose and Undecane are a few significant molecules with larger area percentages that demonstrated biological value. These compounds have been linked to anti-cancer, anti-inflammatory, anti-microbial and antioxidant properties. The current results collectively highlight the appreciable antimicrobial potential of C. collinus and its numerous chemical compounds that are physiologically...
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Posted by admin on Sep 30, 2023 in |
Fluorescein angiography is a commonly used procedure for diagnosing and staging diabetic retinopathy. Diabetic retinopathy is one of the major complications of type 2 Diabetes Mellitus (DM). Patients with diabetic retinopathy are likely to have Chronic Kidney Disease (CKD) as degree of retinopathy correlates with the degree of nephropathy in diabetes. Contrast Induced Nephropathy (CIN) is now defined as an increase of 25% or more in serum creatinine, or an absolute increase of 0.5 mg/dl or more from baseline value, at 48-72 h after exposure to Contrast Media (CM). Although several studies reported the effect of iodinated contrast media on kidney functions especially in diabetic CKD patients, very few conflicting data had been published regarding fluorescein (non-iodinated dye) induced renal injury. Contradictory studies have been reported regarding the effect of fluorescein angiography on renal functions using serum creatinine, estimated GFR (eGFR), so the current research study has been taken to investigate the actual effect of fluorescein on kidney function based on the serum creatinine and early sensitive acute kidney...
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Posted by admin on Sep 30, 2023 in |
Phyllanthus reticulatus Poir., of family Euphorbiaceae was an important therapeutic plant in the traditional medicine, and gaining favour in modern medicine as a plant with varied pharmacological properties. This sericeous shrub is also known as Kirganelia reticulata is widely distributed in India, Thailand, China, Africa and Malaysia. Mouthwash, gargles, mouth spray were formulations were modified using leaves, fruit and stem extract of the plant. The extract of Phyllanthus reticulatus Poir., were studied to have antibacterial, antimicrobial as well as anti-inflammatory activity. Various qualitative tests were performed to authenticate the plant and its property. Presences of alkaloids, phenolic compounds, tannins, coumarins in extract were indicated by the phytoconstituents and UV spectral tests. The extract was found to be stable at acidic state. Fruit extract of Phyllanthus reticulates contain anthocyanin (Delphinidin) which ere detected by TLC and HPTLC. The modified formulations showed good sensitivity towards strains of S. mutans in comparision with marketed product containing Chlorhexidine. The accelerated study proves that the modified products are stable at room temperature. Hence a...
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Posted by admin on Sep 30, 2023 in |
Background: Gastroesophageal reflux disease (GERD) is one of the major gastrointestinal problems around the globe and its effects greatly on individual health, quality of life, social life, and economy. This study is aimed to determine GERD prevalence, risk factors, and management. Methods: It was a cross-sectional study carried out using a validated questionnaire. The data was collected from the general population. The questionnaire consisted of demographic information, personal and habitual data, GERD Questionnaire. The Chi-Square test was used to find the association. Results: The prevalence rate of GERD was found to be about 31%. There was a significant association between GERD and sociodemographic variables such as older age, obesity, profession, do not exercise daily, skipping breakfast, intake of alcohol, fast food, and dinner timing within 1 hour of bedtime, history of illness, family history of GERD, and medication history. The population used both pharmacological and non pharmacological methods of management. The most common method for managing GERD symptoms used by 21.6% of the population was non-prescription or OTC drugs, other methods used...
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Posted by admin on Sep 30, 2023 in |
Background: Stroke is the most frequent clinical manifestation of diseases of the cerebral blood vessels. Up to 90% of post-stroke survivors report one or more disabilities, including impaired walking. Physical rehabilitation and gait training with equipments are essential in the management of post stroke gait disability, however, these techniques are not amenable for hemiplegic patients because of their limitations to actively participate in such training programs. Unani (Greco-Arab) Medicine scholars have been known to treat post-stroke complications on concept of Tanqiya (elimination of morbid matter) and Ta’deel (revitalization of diseased organ) since centuries. Methods: The study was conducted as open, interventional clinical trial, enrolling 30 eligible patients. Tanqiya was done by Mundij (coctives) and Mus’hile Balgham (phlegm purgatives) drugs used in decoction form for 13 days; after Tanqiya, full body Inkibab (steam bath) with Advia Harrah (Hot temperament Drugs) was started from 14th to 28th day of the study for the purpose of Ta’deel. Assessment for gait improvement was performed on valid and reliable scale “FAC” at baseline, 14th...
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