Posted by admin on Feb 1, 2014 in |
The liquisolid technique is a novel concept, where a liquid may be transformed into a free flowing, readily compressible and apparently dried powder by simple physical blending with selected carrier and coating material. The in vitro dissolution property of poorly water soluble Nifedipine was improved by exploring the potential of liquisolid technique. Different liquisolid tablets were prepared by suspending Nifedipine in PEG 400 with Avicel PH 102 as carrier, Aerosil 200 as coating material and Sodium starch glycolate as disintegrating agent. The liquid load factors for liquid vehicle was calculated to obtain the optimum amounts of carrier and coating materials necessary to produce acceptable flowing and compactable powder admixtures viable to produce tablets. The formulated liquisolid tablets were evaluated for post compression parameters such as weight variation, hardness, friability and drug content uniformity. The interaction between drug and excipients in prepared Liquisolid tablets were studied by differential scanning calorimetry (DSC) and FT-IR. The result showed that liquisolid formulation of Nifedipine exhibited higher percentage of drug release than directly compressed...
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Posted by admin on Feb 1, 2014 in |
The genus Swietenia belongs to Meliaceae family which consists of 37 genera and about 300 species which is found in most of the parts of India. In present investigation we made an efficient effort to extract ricinoleic acid from the seed oil of Swietenia humilis, Zucc. They are used in medicine folklore to cure various diseases in Mexico, Africa and India. Physicochemical properties of Swietenia humilis Zucc seed oil were identified along with its fatty acid composition. The structure of the ricinoleic acid was confirmed by IR, NMR and Mass spectral studies. The extracted ricinoleic acid was screened for its antimicrobial and anthelmintic...
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Posted by admin on Feb 1, 2014 in |
Energy drinks (EDs) are caffeine-based beverages that commonly contains large amount of carbohydrates, sugar, health supplements and various energy stimulants, such as ginseng and vitamin B, to name a few. These drinks are marketed for young people actively involved in sports or overworking hours, as natural alternatives that increases fun and improve physical and cognitive performances such as attention, concentration and alertness. There are commonly held false perceptions that the consumption of EDs can rectify the impairment to human physiology because of alcohol consumption including visual reaction time and motor coordination, which is highly required for sports and driving activities, to name a few. The sensory analysis was done in the form of survey. The statistical analysis was done using SPSS software and Analysis of Variance (ANOVA). The graph was obtained between feedbacks (given by the candidates) and number of people for different sensory properties like smell, taste, flavour, texture, and...
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Posted by admin on Feb 1, 2014 in |
The long-term effects of daily consumption of benzene-contaminated water over a period of Sixty-five days on rats’ cellular system were inspected. Haematological parameters such as haemoglobin, packed cell volume etc were determined. Standard enzyme assays were conducted on some enzymes (alkaline phosphatase, acid phosphatase and lactate dehydrogenase) activities of the heart and serum. Significantly lower (P<0.05) enzymes activities were observed in the heart of test rats relative to control. Conversely, enzymes activities in the serum significantly increased. The white blood cell of test rats was found to be 11.3±0.5 while that of control was 9.8±0.6 suggesting infection in the test rats. Haemoglobin, red blood cell count and packed cell volume of test rats were found to be significantly lower (P<0.05) than that of control which may be indicative of anaemia. It could be inferred therefore, that consumption of benzene-contaminated water could pose serious health problems such as heart failure and abnormal haematological...
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Posted by admin on Feb 1, 2014 in |
The present investigation was under taken to find out the effect of stem bark extracts of medicinally important forest tree Oroxylum indicum (L) Kurz on silk production of Bombyx mori. Silk worms were fed with the leaves of mulberry fortified with stem bark extracts of O. indicum. The silk worms were reared up to the end of fifth instar. As the concentration of stem bark extract of O. indicum increased, there was significant increase in the average cocoon weight, pupal weight, shell weight, silk percentage and also filament length of silk. Hence, the stem bark extract of O. indicum can also be considered as cheap and abundant source to enhance the commercial characters of...
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