Posted by admin on Mar 1, 2014 in |
Background: Prescription of drugs which needs to be continuously assessed and refined according to disease progression. It is not only reflects the physician’s knowledge about drugs but also know the pathophysiology of diseases and attitude towards rational prescribing. Methods-: Retrospective study was carried out by collecting 350 prescriptions containing antimicrobial agents of the indoor patients admitted in the wards of medicine department at Sir Sayajirao General (SSG) Hospital, Vadodara. The data was collected by using case record form specially prepared for the study. Results: In our study, total 350 prescriptions containing 539 antimicrobial drugs were prescribed in-patients during study period. Average number of antimicrobials per prescription was 1.54.486 (90.16%) and 53(9.53%) antimicrobials were prescribed by using generic name and trade name respectively. 313(58.07%) and 226(41.93%) antimicrobial agents were prescribed for parenteral administration as well as oral route respectively.188(53.71%) prescriptions constitute single antimicrobial agents, while 162(46.28%) prescriptions contain either two or more than two antimicrobial agents. Among all prescriptions, 4 % and 20% of them were without the age and...
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Posted by admin on Mar 1, 2014 in |
Antihypertensive agents are class of drugs that are used to treat hypertension (high blood pressure) as well as other CVS disorders. Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that reduction of the blood pressure by 5 mmHg can decrease the risk of stroke by 34%, of ischemic heart disease by 21%, and reduce the likelihood of dementia, heart failure, and mortality from cardiovascular disease. Single-dose combination antihypertensive therapy is an important option that combines efficacy of blood pressure reduction and a low side effect profile with convenient once-daily dosing to enhance compliance as compared to monotherapy. The survey enabled to monitor 500 prescriptions and found most available combinations at Savar area in Bangladesh among which beta blockers with Ca-channel blockers was used most (89%) and the brand Fixocard of Incepta was the brand...
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Posted by admin on Mar 1, 2014 in |
In the present study, the alcoholic and aqueous extracts of Thespesia populnea were investigated for their antipyretic activity. Suspension of subcutaneous administration of brewer’s yeast in albino rat leads to pyrexia. Oral administration of extracts at a dose of 500 mg/kg body weight significantly reduced the elevated body temperature of rat. This antipyretic effect has been compared with antipyretic effect of standard paracetamol....
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Posted by admin on Mar 1, 2014 in |
Efficient in-vitro propagation of Tylophora ovata (Lind.) Hook. Ex. Steud was carried out in this present investigation. Nodal segments from the healthy grown plants were used as explants for culturing. Explants were cultured on standard Murashige and Skoog (MS) medium supplemented with different concentration of benzyl amino purine (BAP) and naphthalene acetic acid (NAA) for primary shoot proliferation. Remarkable shoot proliferation was observed in MS medium containing BAP (2.5 mg/L) and NAA (3.5 mg/L). For rooting of the micro shoot, half strength MS medium supplemented with indole acetic acid IAA (2 mg/L) and 3-indole butyric acid IBA (2.5 mg/L) showed the best result. After acclimatization and transplantation, 100% of the in-vitro shoot delivered was found healthy in ex vivo...
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Posted by admin on Mar 1, 2014 in |
ABSTRACT: Background: Coronary artery disease /coronary vascular disease (CAD/CVD) remains the first killer and common silent disease in the world. The lipid profile plays the essential role in CAD development with lipid oxidation. Lipid oxidation, which accepted as an important element of arterial plaque formation and atherosclerosis, is involved in the patho physiology of CVD. Bilirubin exerts a strong antioxidant effects at physiological plasma concentrations against lipid oxidation in blood artery. Methodology: Parameters were measured on a fully automated analyzer using standard reagent kits in a retrospective study involving 100 male Indian subjects between 35 to 55 years of age. Results: Serum total bilirubin was correlated positively with serum high density lipoprotein (HDL), while it was negatively correlated with glycosylated hemoglobin (HbA1c), there were no statically significance present between serum total cholesterol and serum triglyceride in hospitalized patients, not in healthy subjects. Conclusions: we were concluded that, the serum total bilirubin concentration will be an independent cardiovascular risk factor such as lipid...
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