Posted by admin on Sep 1, 2013 in |
Kamrup District of Asasm is bounded by Udalguri and Baksa districts in the north, Meghalaya in the south, Darrang and Kamrup Metropolitan in the east and Goalpara and Nalbari district in the west. The rural part of kamrup district is mostly inhabitated by different tribes such as Boro, Khoronia Kochari, Rajbonghi, and Nepalis. An ethno botanical survey was conducted during the year 2011-2012 in some selected villages to explore the medicinal plants used by the local traditional healers known as ‘bej’ and ‘Ohjha’ for treatment of diabetes mellitus. The data’s were collected using questionnaire and personal interviews with few local healers. The investigation revealed 56 species of plants belonging to 38 families which are used to cure diabetes. These traditional ethno medicinal plants are consumed either in form of juice, powder, or boiled extract of leave, stem, root, seed, fruit, bark, rhizome and flower. In some cases it was found that the whole plant is directly used as potent...
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Posted by admin on Sep 1, 2013 in |
The present study was undertaken to know about the free radical scavenging activity of plants located near Thermal power plant, Mettur, Salem. In this study, Polyalthia longifolia, Derris indica, Holopetela integrifolia, Tamarindus indica, Terminalia tomentosa, Psidium guajava, Nerium indicum, Azadirachta indica, Calotropis gigantea, Ricinus communis, Carica papaya, Ficus benghalensis, Embilica officinalis, Tectona grandis, Ficus religosa, Mangifera indica, Moringa oleifera, Acacia Arabica, Opuntia ficus indica are the plants that were collected during March to April 2013. Among the plants selected, Holopetela integrifolia, Mangifera indica, Tamarindus indica, Acacia arabica, Azadirachta indica were found to have high flavonoid content. Total antioxidant activity was measured in terms of phospho-molybdenum activity was high in Carica papaya when compared to the other entire antioxidant assay, Acacia arabica showed maximum ability to chelate metal...
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Posted by admin on Sep 1, 2013 in |
Bromocriptine mesylate quick release formulation has recently been approved by FDA for the treatment of diabetes mellitus. Till now it has been mainly known for its use in Parkinsonism and for suppression of lactation. Present study evaluates and compares the antihyperglycemic effect of the combination of bromocriptine and metformin with either of the two drugs taken alone. For this fasting blood sugar level of all the groups were measured on day 1,7,14 and 21 of treatment. In this study all the three treatment groups was found to have significant (P<0.05) blood glucose lowering effect. Fall in fasting blood was less in bromocriptine treated group as compared to groups treated with metformin and those treated with combination of the two. It is concluded that hypoglycemic effect of combination of metformin and bromocriptine is better than either of the two drugs taken alone. This may be due to potentiation or synergism between metformin and bromocriptine. Further studies are required to prove that bromocriptine has constantly significant hypoglycemic effect with better safety...
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Posted by admin on Sep 1, 2013 in |
The present work deals with antifertility effect of the aqueous extract of Indigofera trifoliata leaves in female albino rats. Pregnant rats weighing 120 to 200 gm were randomized into 4 groups. From day 11 upto day 15 of pregnancy, rats were laprotomised on 10th day of pregnancy and live fetuses were observed in both the horns of the uterus. Rats in group 1 (control) were orally administered, with 0.5 ml of distilled water once daily while those in group 2 to 4 (experimental groups) were administered 100, 200 and 400 mg/kg body weight doses of aqueous extract of I. trifoliata leaves respectively. Then the animals were allowed to go full term. The effect of aqueous extract of I. trifoliata leaveson estrogenic and antiestrogenic activity and estrous cycle was observed to confirm the antifertility activity. The aqueous extract of I. trifoliata leavesexhibited significant antifertility activity (28.50 to 92.30%). It was found that the extract significantly reduced the number of live fetuses, whereas the resorption index and post implantation losses increased...
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Posted by admin on Sep 1, 2013 in |
To assess the adverse drug reactions (ADRs) induced by antitubercular drugs used in Directly Observed Treatment Short Course (DOTS) from previously reported 8 articles from referred sources. Articles related to adverse drug reactions induced by first line anti- tuberculosis drugs in DOTS therapy published during 2002 to 2012 were searched. The incidence rate of each type of ADR from entire ADRs were analyzed and compared. The total 10083 patients from 8 studies were studied, out of those 7473 (74.11%) patients showed at least one type of ADR. The majority cases of ADRs were dermatological reactions occurred in 4389 (43.52%) patients followed by hepatotoxicity in 1634 (16.20%) patients, other reactions related to gastrointestinal (GI) in 1004 (9.95%) patients, central nervous system in 86 (0.85%) patients,peripheral nervous system in 07 (0.069%) patients, psychiatric in 03 (0.029%) patients, musculoskeletal in 166 (1.64%) patients, renal in 07 (0.069%) patients, otological in 09 (0.089%) patients, ocular in 29 (0.28%) patients, fever in 13 (0.12%) patients, breathlessness in 04 (0.039%) patients, headache in 37 (0.36%) patients...
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