Posted by admin on Dec 31, 2023 in |
Triphala churna is a poly-herbal preparation that has anantiquity of usage in the conventional Indian medical system. It is rich in antioxidants and has excellent therapeutic efficacy. According to ayurveda, the churna is made using the raw ingredients Amalaki (Indian Gooseberry), Haritaki (Indian Hog Plum), and Bibhitaki (Vibheetaki) in an equal proportion (1:1:1). The present investigation purpose was to establish the Triphala’s antimicrobial effect on different types of bacterial stains and its antioxidant effects. Numerous cross checks examinations have been conducted, such as phytochemical detection, physico-chemical analysis, pharmaceutical analysis, to evaluate herbs’ quality attributes, including formulations’ assurance and effectiveness. A comparison of the antioxidant and antibacterial capabilities of polyherbal drug’s aqueous and ethanolic extract follows. Antioxidant activity of Triphala churna was established by FRAP assay and 2,2-diphenyl-1-picrylhydrazyl free radical scavenging methods. By using broth dilution, antibacterial potential was assessed. Triphala reported the presence of valuable bioactive components, including phenols, alkaloids, and flavonoids, which may be in charge of certain biochemical activities, was found, according to the results. Ascorbic acid-like...
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Posted by admin on Dec 31, 2023 in |
Acne vulgaris is a chronic inflammatory disorder of the pilosebaceous unit that affects the major oil gland-containing areas, such as the face, back, and trunk. It involves increased sebum production and hair follicles abnormally desquamate as a result of rising androgen levels that coincide with puberty. It is generally characterized by, the formation of seborrhea, comedones, inflammatory papules, pastures, nodules, and lesions. Propionibacterium acnes and Staphylococcus epidermidis have been identified as bacteria that cause acne inflammation by generating pus. Staphylococcus aureus contributes to causing inflammation in acne. Herbal formulations have growing demand in the world market So, the current research focuses on developing and assessing a herbal face wash against the acne vulgaris and its etiologic agent. The ethanolic extract of Turmeric (rhizomes), Neem (leaves), Black pepper (fruit) and Nutmeg (fruit) was prepared by using a maceration process and formulated into a topical gel. The plants have been used in the formulation the having good anti-microbial, anti-oxidant and anti-inflammatory activity. The gel was formulated with different concentrations of the...
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Posted by admin on Dec 31, 2023 in |
In this study, the anthelmintic activity of Kalanchoe pinnata leaves extract against Indian earthworm Pheretima posthuma was evaluated and compared with the standard drug Albendazole. This activity was concentration dependent. As the concentration increases the extract produce maximal effect. Higher concentrations of ethanolic leaf extract of Kalanchoe pinnata produce a paralytic effect much earlier and time taken for death was shorter. It shows maximum efficacy at 100 mg/ml concentration than the standard drug. The results indicated that the extract had significant anthelmintic activity, as demonstrated by the time of paralysis and death of worms. These findings suggest that Kalanchoe pinnata leaves extract could be a promising natural anthelmintic agent. Further research is recommended to isolate and identify the active principles responsible for its activity, which could lead to the development of new drugs for the treatment of worm infections. This study provides valuable information on the medicinal properties of Kalanchoe pinnata and highlights the potential of natural products as an alternative to conventional drugs for managing parasitic...
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Posted by admin on Dec 31, 2023 in |
Environmental changes influence Physical and Chemical reactions such as pH, Temperature, EC and chemical properties such as Dissolved Oxygen, Organic matter, Silica provide important information on Soil and Water quality different sources of variations and their effects on activities and biodiversity of Soil and Water. In the present study, the Physico-Chemical parameters of Soil sample from Vizag near Bheemili River at location of estuarine region and Water sample from Antarvedi location at sakhinetipalli were compared to provide basic information on the Physical and Chemical characteres in this area of the study. The result shows that there is very little impact on water quality pollution and this study can be used for the quality to maintain aquatic ecosystem, resources, and Agriculture. Reconstruction of the Physico-Chemical properties of Soil and Water in these areas is needed as isolation and characterization of Photosynthetic Bacteria for future...
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Posted by admin on Dec 31, 2023 in |
The objective of this research study is to assess the quality standards of various brands of Metformin hydrochloride tablets that are locally available in Hyderabad, India, by comparing and contrasting them with the brand available in the Jan Aushadhi stores in India (MET-3). Eight brands of Metformin tablets (500 mg) were selected and compared for their physical and chemical parameters as per the official method. The physiochemical equivalence of all tablet brands was assessed through evaluation of both official and non-official standards such as size, shape, uniformity of weight, friability, hardness, disintegration, assay, and dissolution rate. In contrast to the generic drug of metformin available at Jan Aushadhi Kendra (MET-3), the other seven brands of Metformin hydrochloride tablets have all met the requirements of the official I.P. specification regarding weight variation, friability, hardness, disintegration, assay, and dissolution rate. It was concluded that the generic drug of metformin available in Jan Aushadhi Kendra (MET-3), whose price is almost 70% less than the other seven brands of Metformin hydrochloride, is officially...
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