Posted by admin on Jun 1, 2013 in |
Ni(II) and Cu(II) complexes of Schiff base thiosemicarbazones (L1) and semicarbazones (L2) derived from pyrrole-2-carboxaldehyde. These complexes are characterized by elemental analysis, molar conductance measurements, magnetic suscepectibility measurements, mass, IR, electronic and EPR spectral studies. The molar conductance measurements of the complexes in DMSO determine the non-electrolytes and electrolytes nature of the complexes based on their molar conductance value as higher value indicates the electrolytes nature of the complexes and lower value of the molar conductance indicates the non-electrolytes nature of the complexes. On the basis of spectral studies an octahedral geometry may be assigned for Ni(II) complexes except [Ni(L1)2](NO3)2 which are of tetrahedral geometry. A tetragonal geometry may be suggested for Cu(II)...
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Posted by admin on Jun 1, 2013 in |
Background: Glioblastoma Multiforme is the commonest of all astrocytomas. It accounts for 12-15% of all intracranial neoplasm and 50-60% of all astrocytic tumors. Most common site of occurrence is cerebrum and age incidence is highest in fifth and sixth decade. Gliosarcoma constitutes 2% of all brain tumors, 5% of all astrocytomas and 8% of anaplastic astrocytomas. The cell of origin of sarcomatous component has not been fully established. Aim: The purpose of our study is to evaluate histopathological features of GBM in detail, in relation to the age, sex and site of occurrence, in Ganga Ram Hospital, during a period of 10 years and also to find out the relative frequency of Gliosarcoma among glial tumors. Particular emphasis is on to evaluate the nature of glial as well as mesenchymal component and their relationship in Gliosarcoma with the help of immunohistochemistry. Materials: Total of 115 cases of Glioblastoma multiforme were studied histopathologically in detail, with some clinical corelation in Sir Ganga Ram hospital. 13 cases of Gliosarcomas, diagnosed morphologically...
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Posted by admin on Jun 1, 2013 in |
The usefulness of computational methods in drug design process is no longer a point of debate. The contributions from this evolving field have become apparent to both pharmaceutical scientists and academic biomedical researchers. As all the computational drug design are based on statistical and mathematical calculations there is strong evidences present for each and every step, thus research by chance is no longer exist. From statistical analysis of large data set, up to quantitative prediction, one can get simply by seating in front of graphical terminal and using this technique. Success stories from these endeavors are appearing in the literature at an impressive rate. Since the search for new antiviral drugs with reduced toxicity and lower side-effect is continues. Antiviral of class HIV reverse transcriptase are found to have wide range of activities but still this drugs are not very effective in curing HIV infected persons. So this drugs study is carried out and will show more biological and therapeutic activity by performing work of homology modeling and docking...
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Posted by admin on Jun 1, 2013 in |
The present study was undertaken to evaluate the wound healing activity of leaf extract of Dodonaea viscosa Jacq in diabetic wistar albino rats. Wound is defined as a loss or breaking of cellular and anatomic or functional continuity of living tissue. Normal wound healing response begins the moment the tissue is injured. Wound healing is the process of repair that follows injury to the skin and other soft tissues. For the study, various excision, incision and granuloma pouch models were used. In each model, animals were divided into three groups (n=6). Group I was control group, Group II was treated with silver sulfadiazine and Group III was treated with ointment of Dodonaea viscosa. In excision wound model, the significant (p<0.001) increase in rate of wound contraction was observed. Also, there was increase in rate of reepithelization, matrix density and capillary number. The collagen content was found to increase as compared to control. In incision wound model it was found that there was increase in tensile strength. Cotton pellet model...
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Posted by admin on Jun 1, 2013 in |
Background: Job satisfaction represents one of the most complex areas facing today’s managers when it comes to managing their employees. The level of job satisfaction among pharmacy personnel is of importance because it may affect performance and retention. Objective: To assess the level of job satisfaction and factors associated with it among pharmacy professionals working at selected health facilities in south west Ethiopia. Method: Institutional based cross sectional study was conducted among pharmacy professionals working in selected towns, Jimma, Agaro and Limmu Genet, of Southwest Ethiopia from June 30-July 15, 2011 using self-administered semi-structured questionnaires. Statistical analysis was carried out using the Statistical Package for the Social Sciences (SPSS), version 16.0. Participants’ written informed consent to participate in the study was obtained after explaining about the purpose and procedure of the study. Results: Out of 97 pharmacy professionals included in the study, 59 (60.8%) were satisfied and 38(39.2%) were dissatisfied in their job. The major reasons reported for satisfaction were helping the needy 28(28.9%) and professional gratification 23 (23.7%).The major...
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