Posted by admin on Aug 1, 2013 in |
Evaluation of the anti-hepatotoxic activity of methanol-dichloromethane (MDM) extract of Oroxylum indicum (OI) whole plant on carbon tetrachloride (CCl4)- induced hepatotoxicity in rat liver explant cultures (in-vitro) and chronic liver damage in rats (in-vivo). In toxicant (CCl4) treated explants culture set (in-vitro), the marker enzymes GOT, GPT and ALP level increased significantly (p<0.001) when compared to control set. Treatment of CCl4-intoxicated liver explant culture sets with MDM extract of OI whole plant at a concentration of 3.3 mg/ml attenuated the marker enzymes GOT, GPT and ALP levels in culture supernatants significantly (p<0.001) as compared to CCl4 treated explant culture sets. A significant hepatocellular damage as evident from significant elevation in serum activities of GOT, GPT, ALP, bilirubin concentration (total and direct) with decrease in albumin and total protein were found in CCl4: liquid paraffin (1:1) treated animals (in-vivo) when compared to normal values. The MDM extract of OI whole plant (200 mg/kg/day, p.o.) exhibited a significant reduction (p<0.001) in CCl4: liquid paraffin (1:1) induced increased serum levels of GOT,...
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Posted by admin on Aug 1, 2013 in |
The fruit of Phoebe cooperiana U.N Kanjilal ex A. Das is highly priced and one of the most preferred folk food among the Indigenous people of Arunachal Pradesh, India. The methanol extract of fruit collected from East Siang District of Arunachal Pradesh, India were evaluated for total phenolic content, total flavonoid content and antioxidant potential. The methanol extract of fruit were subjected to 2, 2-Diphenyl-1-picrylhydazyl (DPPH) assay for free radical scavenging property and ABTS radical cation scavenging activity to determine antioxidant potential. Folin-Ciocalteu’s method for quantification of total phenolic content and colorimetric method for quantification of total flavonoid content were used in the experiment. Ethnobotany, mode of cooking, demand of fruit in the local market and unscientific harvest from forest and resultant threat on the plant is discussed in the paper. The methanol extract contains considerable phenolic (33.93±1.14 mg GAE/g) and flavonoid (941.5 ±5.31 µMRE/g) but no significant correlation between the total content of phenolic and flavonoid and antioxidant potential was found as IC50 value of 94.6±1.35µg/ml was found ...
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Posted by admin on Aug 1, 2013 in |
Air pollution tolerance index was assessed with plant species located at ChinnaTirupathi, Salem, Tamil Nadu, India. This study was conducted during March, 2013. Since, all the lands are converted to buildings, it is essential to know more about plants and its benefits offered to the environment and the dangers, risks caused by cutting trees. In this study, our aim is to evaluate, whether the plant is toleranant or sensitive to pollution. From the results obtained, we can infer that all the plants collected were having APTI value in the range of 9.41 to 15.46. Selected plants having APTI score of less than 16 are grouped under plants sensitive to pollution and are biological indicators of air pollution. Sensitivity of certain plants to air pollutants is variable from place to...
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Posted by admin on Aug 1, 2013 in |
Nanoparticles of silver (Ag-NPs) have received tremendous research attention for their widespread applications in recent times. The most significant one is their antibacterial properties for which they have been used from food storage to medical supplies. The present study describes a novel green synthesis of silver nanoparticles by using Mangifera Indica and Syzygium cumini leaf extract. The green synthesized silver nanoparticles had been confirmed by UV-Vis spectrum of the reaction media. The UV-Vis spectrum of green synthesized silver from Mangifera Indica and Syzygium cumini have maximum absorbance peaks at 370 and 350 respectively. The Based on the findings, it seems very reasonable to believe that this greener way of synthesizing silver nanoparticles is not just an environmentally viable technique but it also opens up scope to improve their antibacterial...
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Posted by admin on Aug 1, 2013 in |
Traditional knowledge and ethno–botanical use of plants have been widely acknowledged all over the world. In the present scenario, emergence of multiple drug resistance to human pathogenic organisms, this has necessitated a search for new antimicrobial substances from other sources including plants. Combretum albidum, a traditional medicinal liana, used by rural peoples, villagers and tribals residing in different parts of Maharashtra, Tamil Nadu and Kerala, to treat various ailments. The Muthuvans, Chinnar tribe of Idukki district, Kerala is using stem bark of this plant as a remedy for Jaundice. The present study carried out to check the antimicrobial activity of water and methanol extracts of stem bark of C. albidum. The result showed significant antibacterial activity against Escherichia coli, Klebsiella pneumonia, Proteus mirabilis, Pseudomonas aeruginosa, Bacillus subtilis and Salmonella...
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