Posted by admin on Mar 1, 2013 in |
The aerial parts essential oils of Ocimum basilicum (Lamiaceae) from Togo were steam-distilled and investigated for their percentage composition (GC and GC/MS) and in vitro antimicrobial activities. Five oil chemotypes were identified and classified as follows in line with their principal components: estragole type; linalool/estragole type; methyleugenol type; methyleugenol/t-anethole type; tanethole type. The in vitro microbiological experiments revealed that only the methyleugenol and methyleugenol/t-anethole chemotypes were active against tested fungi and bacteria. Their minimum inhibitory concentrations (MIC) ranged from 80-150 μL/L and from 200-500 μL/L respectively. Likewise, on tested bacteria the MIC varied from 200-400 μL/L and from 250-500 μL/L respectively. These findings are supportive of the potential of both basil oil chemotypes for use as active ingredients in natural antibiotic...
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Posted by admin on Mar 1, 2013 in |
An ethnobotanical survey was carried out through semi-structured questionnaire and the guided field-walk method in Islamic University, Kushtia, Bangladesh to document the utilization of medicinal plants by local people for general ailments. A total of 87 species belonging to 51 families with their local names, useable parts and mode of application were recorded for their usages for curing at least 70 ailments. Ethnomedicinally most important families are Asteraceae, Combretaceae, Moraceae, Solanaceae, Apocynaceae. These plant species are utilized by local peoples against various ailments such as dysentery, fever, cough, sexual debility, asthma, skin disease, diarrhea, indigestion, wound healing, toothache, malaria, etc. Indigenous knowledge of Kavirajes or knowledgeable local persons have great contributions in formulating applicable strategy for the development of various medicine using plants as either fresh or raw sources or both. These scattered, selective, fast eroding and highly valuable knowledge needs proper...
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Posted by admin on Mar 1, 2013 in |
Different doses of Ethanolic fraction of Ribes nigrum fruit were evaluated for hypoglycemic activity in Alloxan induced diabetic rats. The oral administration of Ethanolic extract at a dosage of 100mg/kg and 500mg/kg body weight exhibited significantly reduced the serum glucose level in both acute (1, 3, 5 h) and sub-acute (1, 3, 5, 7 days) treatments. Perform the Histopathological study of...
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Posted by admin on Mar 1, 2013 in |
In the present study, three medicinal plants Cynodon dactylon (L.) Pers, Cassia tora Linn. and Cassia alata Linn having significant anti-inflammatory potential were selected to be formulated as polyherbal gels. The gels were prepared using the dried methanolic extract of Cassia tora Linn, Cassia alata Linn and Cynodon dactylon (L.) Pers. Polyherbal gel formulations were evaluated for its pH, appearance and homogeneity, viscosity, spreadability and skin irritation studies. Assessment of Anti-inflammatory activity was done by carrageenan induced rat paw edema and formalin- induced rat paw edema. Individual and polyherbal gel of Cassia alata Linn,Cassia tora Linn. and Cynodon dactylon (L.) Pers were found to possess anti-inflammatory effect in acute and chronic models. Polyherbal gel also showed synergistic effect as compared to individual gels which can be useful for the treatment of local...
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Posted by admin on Mar 1, 2013 in |
An accurate, precise and reproducible high performance liquid chromatographic method was developed for quantitative estimation of hydrochlorothiazide in tablet dosage forms. Chromatographic separation of the drug was achieved on a Kromasil C18 column (150 x 4.6 mm; 5µ) using a mobile phase consisting of phosphate buffer (pH 2.5) and acetonitrile (50:50 v/v) at a flow rate of 0.6 mL/min. The drug in the eluate was monitored at 254 nm. The retention time obtained for the drug was 3.47 min. The calibration curve was linear over the range of 20-60 µg/mL of the drug. The performance of the method was validated according to ICH guidelines. The method could be applied for determination of hydrochlorothiazide in its tablet dosage forms without any interference from excipients or endogenous substances. The proposed method is suitable for routine quality control analysis of...
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