Posted by admin on Mar 1, 2013 in |
Ficus religiosa L (Moraceae) is widely distributed in northern part of India has traditionally been used in India as medicinal plant for the treatment of diarrhoea and dysentery. In the present study ethanolic extract of Ficus religiosa L was used for investigation of antiulcer activity by using pylorus ligation as antisecretory model and ethanol induced ulceration models as cytoprotective model. Animals pretreated with ethanolic extract of Ficus religiosa L at the dose 200 mg/kg and 400 mg/kg showed significant decrease in ulcer index and percentage ulcer protection in all models. The results suggested that the extract at 200 mg/kg and 400 mg/kg showed significant protection (P<0.001) by reducing ulcerative lesions when compared with control group of animals. These findings indicate that Ficus religiosa L. bark and rootextract shows significant antiulcer...
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Posted by admin on Mar 1, 2013 in |
A simple and sensitive visible spectrophotometric method is described for the assay of risperidone (RSP) in pure and solid dosage forms. The method involves oxidative coupling of risperidone with MBTH in presence of ferric chloride dissolved in HCl and apple green chromogen is formed and exhibits absorption maxima at 595.8nm. Regression analysis of Beer-Lambert plots showed good correlation in the concentration ranges (10-80) μg/mL. Regression coefficient was found to be 0.992. The proposed method is applied to commercial available tablets and the results are statistically evaluated and validated by recovery studies. The proposed methods have been successfully applied to the analysis of the bulk drug and its tablet dosage form. The methods have been statistically evaluated and were found to be precise and...
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Posted by admin on Mar 1, 2013 in |
With respect to Chhattisgarh, rice is the principal crop of the state. India Covers 66% of cultivable land and mostly grown under kharif cropping season. To increase sustained productivity without decreasing soil quality, algal bio fertilizers are used widely now days in the state. Use of local isolates as algal inoculants is being stressed due to their competitiveness in the field for establishment of better ecological adaptability for developing composite starter. Culture of algal bio fertilizer programme on a regional basis, survey, isolation and screening of stress-tolerant cyanobacteria have been started at various parts of India. The soils of Chhattisgarh state comprise mostly of iron- rich red soil, laterite soil, and red and yellow soil and brown forest soil. So the above study comprises the characterization of physical and chemical properties collected from 4 districts of Chhattisgarh...
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Posted by admin on Mar 1, 2013 in |
Alzheimer’s disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills, reasoning, planning, language, and perception, and eventually even the ability to carry out the simplest tasks. Many scientists believe that Alzheimer’s disease results from an increase in the production or accumulation of a specific protein (beta-amyloid protein) in the brain that leads to nerve cell death.The brains of people with AD have an abundance of two abnormal structures amyloid plaques and neurofibrillary tangles that are made of misfolded proteins. This is especially true in certain regions of the brain that are important in memory. In people with Alzheimer’s disease, deposits called amyloid plaques build up in the brain. These are composed, in part, of a protein called beta-amyloid, which is a fragment of the amyloid precursor protein (APP).A mutation in the gene that makes APP is believed to be responsible for 5 to 20 percent of all early onset familial Alzheimer’s disease. People with a mutation in the APP gene tend to develop...
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Posted by admin on Mar 1, 2013 in |
Turmeric (Curcuma longa) is a rhizomatous herbaceous perennial plantused as a food additive. It has been reported that rhizome of this plant have antibacterial, antifungal, anti-inflammatory, antioxidant and antitumor property. Methanol extract of Rhizome of Curcuma longa was investigated here to see the antimicrobial actions and anti-inflammatory effect. During the extraction process a purified single compound (D1) was isolated and investigated for its antimicrobial activity. Significant antimicrobial activity than penicillin were found for 500µg C. longa extract. Anti-inflammatory action of C. longa was also assessed using mice models. The purified compound D1 fraction showed antimicrobial action in 50µg concentration. Our study reveal that C. longa has antimicrobial activity against various gram positive and gram negative bacteria where curcumin may not be the only compound that is responsible for the antimicrobial activity. On the other hand, C. longa extract had shown significant anti-inflammatory...
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