Posted by admin on Jan 1, 2013 in |
Mucilaginous exudates from Aloe leaf containing polysaccharides, of which the major proportion has been reported to be composed of acetylated mannose molecules such as Acemannan and other high molecular weight polysaccharides. These polysaccharides, have been reported to elevate the Granulocyte Macrophage Colony Stimulating Factor (GMCSF) ultimately leading to the infiltration of macrophages at respective sites. This immunological property has been exploited to test the efficacy of dried aloe mucilaginous extract containing these high molecular weight polysaccharides for anti-fertility activity. The polysaccharides were extracted by ethanol precipitation method. The suspension of extract in aqueous medium was prepared under aseptic environment to ensure the desired sterility. Characterization of extract was done by spectrophotometry and IR spectroscopy. The results suggest the presence of biologically active polysaccharides. The preliminary finding of the experiment confirms the anti-fertility activity in rats. However, a mild edema was observed in the uterine horns of the test group animals which subsequently reduced in severity upon reducing the dose. The cause of the oedema could be attributed to the...
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Posted by admin on Jan 1, 2013 in |
Patients want and are seeking more information about drug and nondrug treatment options. While a great deal of patient information about medications, treatments, and diseases exists, much of it contains conflicting, inaccurate, poorly written, or non–evidence-based information. The objective of the study was thus, to assess what patients want to know about their medications at Gondar University Hospital. The study was conducted in Gondar University Hospital over 1 month period from March 1- 30, 2012. Data was collected using convenience sampling technique from 384 respondents using structured questionnaire which consists of 40 items. All data collected were then analyzed using the Statistical Package for Social Sciences (SPSS), v19 software. In the study 238 (68%) male and 146(32%) female patients were included. From the total questions forwarded for the total population 165(43%) responded drug information as very relevant, 156(40.6%) responded drug information as relevant, 40(10.4%) responded drug information as somewhat relevant and 23(6%) answered drug information as not relevant. Concerning drug information source the result showed that 49%, 49% and...
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Posted by admin on Jan 1, 2013 in |
A qualitative ethnopharmacological survey was carried out among a local Orang Asli tribe to gather information on the use of medicinal plants in the region of Kampung Buluh Nipis. After meeting and interviewing some informants we have gotten some few traditional plants and treatment used by Orang asli people in their daily life. After Study the results showed that majority of the Orang Asli, of Kampung Buluh Nipis are still dependent on local plants as their primary source of medication. Preservation and recording of ethnobotanical and ethnopharmacological uses of traditional medicinal plants is an indispensable obligation for sustaining the medicinal and cultural resource of mankind. Extensive research on such traditional plants is of prime importance to scientifically validate their ethnopharmacological...
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Posted by admin on Jan 1, 2013 in |
The performance of whole building depends on many factors: structure, coating, environment, climate, type of use, service etc. Fungi are essential for the survival of our global ecology but they may pose a significant threat to the health of occupants when they grow in our buildings. The most important factor that affect microbial growth on buildings materials are temperature, moisture and nutrients. The moisture conditions connected with temperature and exposure time are the most important factor for the development of biological problems and damage in buildings. In vitro studies were conducted on the effect of temperature, pH levels and moisture on the growth of Aspergillus flavus and Penicillium chrysogenum. Maximum growth was observed on pH level 6 and 7 against A. flavus and P. chrysogenum respectively after 12 days. The most suitable temperature for the growth of A. flavus and P. chrysogenum was observed on 25°C and 30°C respectively. The fungus showed maximum growth at 90% relative...
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Posted by admin on Jan 1, 2013 in |
A series of 1, 3, 4-oxadiazole derivatives were designed and out of which six compounds have been synthesized via four step synthetic scheme and evaluated for antibacterial activity using cup plate method. The compounds were previously characterized by IR, 1H-NMR spectral analysis. The compounds with hydroxyl and methoxy substituted phenyl rings showed higher activity than the chloro substituted derivatives and standard i.e vancomycin. The antibacterial study revealed that the most promising compounds are 3-(4-hydroxyphenyl)-1-(5-(2-hydroxyphenyl)-2-phenyl-1,3,4-oxadiazol-3(2H)-yl prop-2-en-1-one 6.4(a), 3-(4-methoxyphenyl)-1-(2,5-di phenyl-1,3,4-oxadiazol-3(2H)-yl)prop-2-en-1-one 6.4(b), 3-(4-hydroxy phenyl)-1-(2,5-diphenyl-1,3,4-oxadiazol-3(2H)-yl)prop-2-en-1- one 6.4(c), 3-(4-hydroxy phenyl)-1-(2-(4-hydroxyphenyl)-5-phenyl-1,3,4-oxadiazol-3(2H)-yl)prop-2-en-1-one 6.4(e), 1-(2-(4-hydroxyphenyl)-5-phenyl-1,3,4-oxadiazol-3(2H)-yl)-3-(4-methoxy phen yl)prop-2-en-1-one 6.4(f) against the tested bacteria (S. aureus, B. subtilis, P. aerugenosa, E. coli). This preliminary study revealed that these compounds may be used as potential leads for further...
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