Posted by admin on Dec 1, 2012 in |
This research was targeted to reveal the phytochemical activity of Casuarina equisetifolia against susceptible pathogenic oral bacteria. Antibacterial effect of the plant was examined by well diffusion method. Different plant parts were screened for the phytochemicals using various polar solvents like ethanol, acetone, methanol, chloroform and water. Studies disclosed that Casuarina equisetifolia encompasses a wide range of phytochemicals with anticariogenic activity. During phytochemical analysis by thin layer chromatography four compounds were obtained in the acetone solvent system with highest Rƒ value of...
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Posted by admin on Dec 1, 2012 in |
Enzyme engineering is a fast-growing application in the pharmaceutical market. Enzymes are key to new processes because they are environmentally friendly and reduce hazardous waste. The uses of immobilized enzyme eliminate the enzyme separation step from the main process thus simplifying and increasing the overall process yield. The use of immobilized enzyme has several advantages as compared with an application of free enzymes. Immobilized enzymes can be recovered from reaction mixture and can be made available for reuse again. This work was undertaken to study the rate and duration of digestion of Bovine Serum Albumin by pepsin in free enzyme and immobilized states. Immobilization of pepsin was done by entrapment in calcium chloride. After studying the observations, it is found that in the reaction catalyzed by free pepsin, after a certain period of time; there was no more increase in optical density even if the enzyme concentration was increased. This indicates that the total liberation of amino acids related with increased absorbance gets in limiting stage due to exhaustion...
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Posted by admin on Dec 1, 2012 in |
In present study, a series of new synthesized condensed pyrazole derivatives 1a-f have evaluated in vitro for their antioxidant activity, reducing power ability, antibacterial activity against Gram-positive and Gram-negative organisms and antifungal activity against different organisms. Minimum inhibitory concentration against the bacterial and fungal strains was determined. The study provides the structural impact of the compounds for their biological...
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Posted by admin on Dec 1, 2012 in |
Synthesis of chalcone derivatives was carried out by aldol condensation, these 2’-hydroxychalcones were cyclized to 3-hydroxyflavone and 2, 3- dihydroflavan-3-ol derivatives and we also report here there in vitro antiplaque activity. Most of the synthesized compounds were found to be active against Streptococcus mutans. Activity of two 3-hydroxyflavones was found to be higher than that of their corresponding 2, 3- dihydroflavan-3-ol derivatives and chalcone analogues. Investigated compounds having hydroxy group substituents in ring-B exhibited enhanced activity and the presence of electronegative groups in the studied compounds showed a direct relationship to the antiplaque...
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Posted by admin on Dec 1, 2012 in |
Significant increase in the salivary gland lipid peroxidation, fluorescence product as well as accumulation of lipofuscin granules–age pigment was observed after injection of 5% D-galactose 0.5 ml daily for 30 days. Supplementations of turmeric extract (30mg/kg body weight) for 30 days during and after D-galactose treatment significantly reduced all the above parameters. Histochemical changes in the form of accumulation of age pigment were observed in the submandibular gland (SMG) of experimental animals. The normalization of levels of all the studied parameters in the SMG by curcumin supplementation in D-galactose induced aging accelerated mice is suggestive of the possible ameliorating effect of curcumin on SMG. While in curative group II the levels of all parameters were elevated as compared to D-galactose treated group...
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