Posted by admin on Nov 1, 2012 in |
Couroupita guianensis (Lecythidaceae) , is a medicinal plant which is endowed with curative properties including anti- fungal, anti – biotic, anti – septic, analgesic, anti-malaria, stomach – ache, tooth – ache, scabies, gastritis, bleeding piles, dysentry and scorpion poison. The study deals with the preliminary phytochemical screening of the stem of Couroupita guianensis with various extracts such as petroleum ether, benzene, ethanol and water. This includes the powder characteristics studies, fluorescence studies and thin layer chromotgraphic studies of the stem powder. The qualitative analysis of some secondary metabolites, to ascertain medicinal claims of this widely used medicinal plant. The results showed that the moderate presence of alkaloids, flavonoids, steroids, amino acids, phenols and...
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Posted by admin on Nov 1, 2012 in |
Clinacanthus nutans Lindau (Family: Acanthaceae) has attracted public interest recently due to its high medicinal values for the treatment of cancer, inflammation and various skin problems. This study was aimed to determine the oral LD50 value of the methanol leaves extract of C. nutans and identify the targeted organs in mice. This acute oral toxicity study was conducted in accordance to OECD 423 guidelines by using male Swiss albino mice weighing 25-35 g. First group was served as control group which received distilled water (vehicle) while second and third group were orally treated with single daily dose of 0.9 g/kg and 1.8 g/kg of methanol leaves extract of C. nutans, respectively. All the animals were closely observed for 14 days. Body weight for each mouse was recorded at day-0, day-3, day-7 and day-14. Relative organ weights for liver, kidney, spleen, lung and heart were also determined. All the results were presented as mean ± standard deviation and analyzed using Dunnett’s Test after ANOVA test. From the results obtained, no...
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Posted by admin on Nov 1, 2012 in |
The anti-ulcer activity of aqueous extract of Annona squamosa leaves was investigated on a indomethacin induced ulcer models in wistar rats. In model the common parameter determined was ulcer-index. aqueous extract of dosage 175, 350 mg/kg p.o produced significant inhibition of gastric lesions induced by indomethacin induced ulcers. The extract 175mg/kg & 350mg/kg showed significant (p<0.01) reduction in gastric volume, free acidity and ulcer index as compared to control. This present study indicate that Annona squamosa leaves extract have potential anti ulcer activity. This results may further suggests that aqueous extract was found to posses antiulcerogenic as well as ulcer healing property,which might be anti secretory...
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Posted by admin on Nov 1, 2012 in |
The present study was designed to investigate the antidiabetic potential of different extracts of Berberis aristata bark, in alloxan induced diabetic male wister albino rats (150-250g), Diabetes was confirmed after 5 days of single intraperitoneally injection of alloxan (140 mg/kg of body wt.) in 12 hours previously fasted rats. Petroleum ether extract of Berberis aristata (PEBA) (100 & 400 mg/kg, body wt.) & Ethanolic extract of Berberis aristata (EEBA) (100 & 400 mg/kg, body wt.) and the standard drug glibenclamide (10 mg/kg, body wt.) were given orally in 0.5% Tween 80 after 5 days of alloxan treatment daily for 20 days, except the normal and diabetic control group (n=6). Blood was collected from the retro orbital sinus of the rats for glucose, total cholesterol and triglyceride level determination on 1st, 5th, 10th and 20th days. PEBA (100 & 400 mg/kg, body wt.) showed significant reduction in blood glucose level (266.3 ± 0.9700 to 118.1 ± 0.9375mg/dl & 271.3 ± 0.6983 to 111.6 ± 0.8072 mg/dl, respectively), total cholesterol (92.40±0.7711mg/dl...
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Posted by admin on Nov 1, 2012 in |
Punica granatum L. belongs to the family Punicaceae, which is originating from the Middle East, extending throughout the Mediterranean, eastward to China and India. Punica granatum has been used extensively as a traditional medicine in many countries for the treatment of dysentery, diarrhea, helminthiasis, acidosis, hemorrhage and respiratory pathologies. In addition, P. granatum is reported to have antioxidant, anti-atherosclerotic and antiviral properties. The dried pomegranate peels (20gms) were extracted using water (100ml) & ethanol (100 ml). The Ethanolic Extract of Punica granatum (EPG) was active against the tested bacteria. EPG demonstrated promising antibacterial activity against tested gram positive and gram negative bacteria. The E. coli and S. aureus shows more susceptibility to...
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