Posted by admin on Nov 1, 2012 in |
The phytochemical constituents of Borassus flabellifer was identified and evaluated the antibacterial activity of the acetone, benzene, chloroform, ethanol and methanol extracts. A phytoconstituent analysis of alkaloids, glycosides, terpenoids, steroids, flavonoids, tannins, phenols and saponins were performed on the various solvent extracts. Antibacterial activity was analyzed by agar well diffusion method against five pathogenic microorganisms, E. coli, S. aureus, K. pneumonia, P. aeruginosa and B. subtilis. The maximum zone of inhibition was exhibited for E.coli (14mm); P. aeruginosa (13mm) and B. subtilis (11mm)against compared to tested micro organisms. The methanolic extract of the palm root has showed consistently significant inhibitory activity on different bacterial species tested. Furthermore, identification of bioactive compounds will be...
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Posted by admin on Nov 1, 2012 in |
The study describes a validated reverse-phase HPLC method for the simultaneous estimation of paracetamol and naproxen in bulk and in tablet formulation. The proposed RP-HPLC method utilizes Eclipse XDB C18 column (150 ×4.6 mm i.d., 5 µm), optimum mobile phase consisted of gradient run of initial ratio of water (pH-2.5 adjusted with orthophosphoric acid): acetonitrile (87:13) with the effluent flow rate of 1.0 ml/min, and UV detection wavelength 263 nm. The developed method was statistically validated for linearity, precision, robustness, ruggedness and specificity. The method was linear over the range of 5-80 µg/ml for paracetamol and 3-48µg/ml for naproxen. The mean recovery was 99.72% and 100.88% for paracetamol and naproxen respectively. The intermediate precision data obtained under different experimental setup was quite concurrent with less critical % RSD. The proposed method can be useful in the quality control of paracetamol and naproxen in bulk drug and drug...
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Posted by admin on Nov 1, 2012 in |
The paper describes the in-vitro antioxidant activity of seed oil extracted from seeds of Mesua ferrea L. The plant extract has been found to possess various pharmacological activities which have been proved scientifically based on the ethnomedical data. The in-vitro antioxidant activity of M. ferrea seed oil (MFSO) was evaluated. The EC50 values of free radical scavenging activity (10.25 µg/ml), ABTS+ (652.5025 µg/ml) discoloration assay and nitric oxide scavenging activities (13.17 25 µg/ml) and determination of total phenolic content (121.5 µg GAE/ml), total antioxidant content 241.25 µg GAE/ml and total flavonoids content (66 µg QE/ml) in MFSO indicated its potential antioxidant...
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Posted by admin on Nov 1, 2012 in |
Thermal power plants produce enormous quantity of pollutants such as fly ash as a by – product of combustion of coal or any pulverized fuel at higher temperature. Industrial effluents contain several heavy metals including cadmium distrusted the metabolic process of living organism due to easily dispersion and mobilization in environment. The eatables and applicable potential plants and vegetables altered by Cadmium and concern derivatives which directly and indirectly posing severe risks to human health which, extremely toxic even in low concentration, and will bioaccumulate in organisms and ecosystems. Interest has therefore risen in its bio hazardous potential. Present study deals on monitoring or current status of cadmium in certain plant and common vegetable species in singrauli region, resulted indication were observed an alarming situation in Singrauli region of...
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Posted by admin on Nov 1, 2012 in |
Binahong (Anredera cordifolia (Ten) Steenis) has been used as wound healing in traditional Indonesian medicine and it is relevant to develop dosage forms of binahong using formulation technology approach. The aim of this research was to find out wound healing gel formula of ethanolic extract of binahong. The factorial design method 3 factors and 2 levels were employed to achieve this study. Three factors used in this study were Carbopol, Na-CMC and Ca-alginate with low and high level for each factor. The wound healing gel of ethanolic extract of binahong was evaluated for their physical properties i.e viscosity, spreadability, extrudability and bioadhesive properties. The results of this research were carbopol and Ca-alginate affecting physical properties of wound healing gel of ethanolic extract of binahong. Na-CMC affected physical properties of the gel except bioadhesive properties. Carbopol provided the greatest contribution to viscosity, spreadability, extrudability and bioadhesive properties of the...
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