Posted by admin on Jun 1, 2012 in |
Phellinus and Ganoderma are a folk medicinal, wood inhabiting fungus, recently been studied for its pharmacological activities. In the current study, Acetone, Methanol and ethyl acetate extracts were prepared from species of Phellinus and Ganoderma. The active compounds of acetone and methanol extracts have the same polarity but they show different activity. The antimicrobial assay showed zone of inhibition against different strains of Acinetobacter and acetone extract gave best results. Therefore, the extract of Phellinus may contain different bioactive compounds like sesquiterpens, triterpens etc that may act on Acinetobacter. A significant broad spectrum anti-bacterial activity from Phellinus spp. was revealed through the...
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Posted by admin on Jun 1, 2012 in |
Candida albicans is one of the most important fungi associated with oral candidiasis and the treatment of this fungi is a serious problem today because of the resistance of these fungi against conventionally used drugs. So, there is an urgent need of alternative antifungal substances especially from the natural sources. The study was conducted to examine the MFC and time kill activity of two stilbenes [3, 4′, 5-trihydroxystilbene (1) and 3,5-dihydroxy-4-isopropylstilbene (2)] purified from a bacterium associated with entomopathgenic nematode against C. albicans. The activity was also compared to amphotericin B. The cytotoxicity of stilbenes was also tested against normal human cell lines (L231 lung epithelial and FS normal fibroblast). Results showed that stilbenes was effective against C. albicans with MIC and MFC of 64 and 128 µg/ml for compound 1 and 32 and 64 µg/ml for compound 2. The time kill assay of stilbenes against C. albicans was more effective than amphotericin B. No cytotoxicity was recorded for stilbenes upto 200 µg/ml. The strong antifungal activity and low...
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Posted by admin on Jun 1, 2012 in |
Typhoid fever is serious public health problem in many parts of the world.Typhoid fever, also known as enteric fever, is an illness caused by the bacterium, Salmonella typhi. The immunology of typhoid fever in man has been the subject of a recent review. The diagnosis and subsequent treatment could reduce infection complication towards acute illness. It is difficult at present time, to diagnose typhoid fever early in its course. The immunological assay can be designed for the earlier detection. The detection of specific bacterial antigen from body fluid and serum was suggested to be an important diagnostic method in infections disease. The EIA i.e., Enzyme Immuno Assay can be carried out which is found to be very significant. The results are discussed here in relation to the concept of detection of fever in early...
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Posted by admin on Jun 1, 2012 in |
The study was aimed to evaluate the anticancer activity of the Soft Halicona species on the HeLa cell line. The Soft Halicona species methanol and Dichloromethane extracts were tested for its inhibitory effect on HeLa cell line. The percentage viability of the cell line was carried out by using colorimetric method. The cytotoxicity of Soft Halicona specieson HeLa cell was evaluated by MTT assay. Both the methanol and Dichloromethane extract has significant cytotoxic effect on HeLa cell line in concentration range between 0.1µg/ml to 100µg/ml by using MTT assay. R2 value of Soft Halicona species on HeLa cell of methanol extract was 0.8316 and for dichloromethane extract was 0.6699 and percentage cell inhibition for methanol extract 61.40% and Dichloromethane extract was 46.98%....
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Posted by admin on Jun 1, 2012 in |
The regulatory authorities are now focusing on the regulatory issues of traditional medicines under which Unani system of medicine falls. Today we are witnessing an increase in the use of traditional medicines throughout the world raising the questions as to how safe these preparations are. People are now bending towards the Unani system of medicine because of its safety, efficacy and lesser side effects and hence raising the popularity of the Unani system of medicine. The major problem associated with Unani system of medicine is the lack of regulatory issues that ultimately leads to counterfeiting of Unani medicines. In the present article an endeavour has been made to present an overview of Unani system of medicine with special attention towards the Unani Cosmeceuticals products. This article intends to contribute towards the regulatory knowledge by giving a survey of published information regarding the regulations of the Unani Cosmeceuticals products. This article also focuses on the good manufacturing practices along with the standards for Unani Cosmeceuticals drug contents. This present article...
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