Posted by admin on Nov 1, 2011 in |
Comparative pharmacognostic and phytochemical studies are the reliable source to identify the genuine raw drug from its adulterants. This paper deals with the characterization of the repute ayurvedic drug hallakam from its substitute/adulterants. Ayurvedic experts equated rhizomes of Kaempferia rotunda L. of Zingiberaceae as hallakam and in certain market samples Lagenandra toxicaria Dalz. is also sold as hallakam. The distinguishing pharmacognostic and phytochemical characters evolved from the study help to detect the genuine and market adulterant of...
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Posted by admin on Nov 1, 2011 in |
Metal complexes of Au(III) with Thiosemicarbazone and Substituted Thiosemicarbazones different thiosemicarbazones have been synthesized. The present communication reports the structural study of the Au(III) complexes with Biacetyl Monoxime Thiosemicarbazones and these complexes have been characterized by elemental analysis, conductance, IR, NMR and Mass spectral data. The physicochemical and spectral data suggests tetrahedrol geometry for various complexes. Metal complexes of Biacetyimonoxtme thiosemicarbazone (BAMOT) and Substituted Thiosemicarbazones are also investigated for better comparison. Au(III) complexes of Biacetyimonoxtme thiosemicarbazone (BAMOT) and Substituted Thiosemicarbazones are also investigated for better comparison. The ligand and metal chelates would be screened in vitro for anticancer activity against some cancer Cell...
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Posted by admin on Nov 1, 2011 in |
The human oral cavity is a complex biological system in which members of a microbial community interact with themselves as well as with different host structures and components Neisseria sp., Haemophilus influenzae and Campylobacter jejuni cause periodontitis . The pathogenesis of this dental infection is a multi factorial process that results in a serious degenerative disease of the periodontium. Researches have resulted in the identification of important virulence factors. These researches have provided a narrow picture of the steps of this complex process. In contrast, a wider picture could be abstained with the application of tools such as bioinformatics and proteomics. These tools provide factors and process leading to the pathogenesis and treatment. In the present study Ferric binding protein is taken as a case study molecule to understand high reactive responses of various drugs administered for the oral periodontitis. The drugs are being compared with the Fbp. The Fbp interacted with doxycycline, flurbiprofen and chlorhexidine using docking...
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Posted by admin on Nov 1, 2011 in |
The antiulcer activity of ethanolic extract of Calotropis gigantea R.Br leaves (EECG) was investigated in pylorus ligation and ethanol induced ulcer models in experimental rats. In both models the common parameter determined was ulcer index. Ethanolic extract of Calotropis gigantea at a dose of 150 and 300mg/kg produced significant inhibition of the gastric lesions induced by pylorus ligation induced ulcer and ethanol induced gastric ulcer. The extract (150mg/kg and 300mg/kg) showed significant (p<0.05) reduction in gastric volume, free acidity and ulcer index as compared to control. This present study indicates that EECG have potential anti-ulcer activity in both models. These results may further suggest that the extract was found to possess antiulcerogenic as well as ulcer healing properties, which might be due to its antisecretory...
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Posted by admin on Nov 1, 2011 in |
The plant Acalypha indica Linn. is commonly known as Indian Acalypha and it belongs to the family Euphorbiaceae, found in all parts of the tropics. This herbs found in fields and wastes places throughout the hotter parts of the world. The plant has wide uses in the traditional medicines of various countries and reportedly possesses diuretic, purgative and anthelmintic properties, besides being also used for bronchitis, asthma, pneumonia, scabies and other cutaneous diseases. In the present study different extract of Acalypha indica plant was evaluated on fasting and posts prandial blood sugar in both insulin and non insulin dependent diabetes mellitus rats. The induction of diabetes was done by using streptozotocin in neonates. Oral administration of petroleum ether, chloroform, acetone and methanol extracts of the bark (100 mg/kg, p.o.) for 21 days caused a decrease in fasting blood sugar (FBS) in diabetic rats. Among all the extracts, methanol extract was found to lower the FBS significantly (P<0.001) in diabetic rats. Methanol extract also caused a significant decrease (P<0.01) in...
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