Posted by admin on Aug 1, 2011 in |
Incidence of cancer in northeast is the highest in India. Nutrition intervention plays a vital role in the management of postponement of cancer. Objectives: To find out the prevalence rate of different types of cancer among the selected male tribal population of Shillong and dietary habits of these tribes the present study was carried out. Methods: Three hospitals from the city of Shillong was followed up for a period of three months, a total of 125 male inpatients and outpatients visiting during the period were interviewed with well-structured interview to collect data on background information, disease history, anthropometric measurement, clinical assessment, biochemical assessment, lifestyle or health hazards, dietary hazards and dietary assessment including weighment survey to assess for the nutrient intake of the cancer patients for three consecutive days. The PGSGA scoring was done to find the suitable level of intervention strategies. Nutrition intervention through Macrobiotic Approach was given to the patients and their family members using pamphlets, booklet and an e-content. Results: It was found out during the...
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Posted by admin on Aug 1, 2011 in |
Bindens pilosa L. is a cosmopolitan weed, originally from South America and common in all tropical and subtropical areas of the world. It is a small annual weed occurring all over the country. Roots, leaves and seeds have been reported to possess antibacterial, antidysentric, anti-inflammatory, antimicrobial, and hypotensive activities. Extracts of this plant is used in southern Africa to cure malaria. In tropics also it is used on snakebite and malaria. It is used in traditional medicine as a remedy to treat glandular sclerosis, wounds, colds, flu and urinary tract infections. Leaf extracts in petroleum ether, chloroform, acetone, methanol and distilled water were tested against five bacteria. Maximum zone of inhibition was produced by acetone and petroleum ether extract against Proteus vulgaris, and least activity by methanol and aqueous extract against bacillus...
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Posted by admin on Aug 1, 2011 in |
Since ancient times, plants have got medicinal importance. Ethno medicinal use of plants is very common in rural parts of India. Various constituents of these plants have shown profound therapeutic and prophylactic activities. The present research work is conducted to investigate invitro antimicrobial activity of various extracts of seeds of plant Cleome viscosa Linn. The petroleum ether, chloroform, ethyl acetate, ethanol & water extract of seeds of plants were screened against eight microbial species. Clinical samples of pus from earache patients were also used. The test materials have shown significant antimicrobial activity. The zones of inhibition are found to be between 10 mm to 17 mm. The minimum inhibitory concentration (MIC) values of extracts are also determined against microorganism which ranges from 0.1 to...
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Posted by admin on Aug 1, 2011 in |
In present study, a successful attempt has been made to develop a simple method for the simultaneous determination of ofloxacin and ornidazole using linear sweep Voltammetry (LSV) technique. Quantification of ofloxacin and ornidazole was done in Britton-Robinson Buffer of pH 5.5 using 0.1M KCl as a supporting electrolyte. Both ofloxacin and ornidazole exhibit reduction cathodic peak in given pH with peak potential at -1.30 V for ofloxacin and -0.42V for ornidazole vs. S.C.E. 0.1N HCl was used as Solvent for the analysis. The method was validated in the terms of its linearity, accuracy, precision, robustness, ruggedness, LOD and LOQ. Proposed method was found to be simple, precise, and accurate and can be successfully applied for routine quality control analysis and simultaneous determination of ofloxacin and ornidazole in combined drug formulations....
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Posted by admin on Aug 1, 2011 in |
The present work was carried out to design the floating drug delivery system to minimize the side effect, improve the prolongation of action, to reduce the frequency of administration. The objective of the present investigation was to develop a bilayer-floating tablet (BFT) and evaluate for domperidone maleate using wet granulation technology. HPMC, K-grade and effervescent sodium bicarbonate formed the floating layer. The release layer contained domperidone and various ratios of polymers such as HPMC-K100M.The floating behavior and in vitro dissolution studies were carried out in a USP paddle apparatus 2 in simulated gastric fluid. Final formulation released approximately 104% drug in 12 h in vitro, while the floating lag time was 4 min and the tablet remained floatable throughout all studies. Statistically significant differences were found among the drug release profile from different formulations Final formulation followed the Higuchi release model and showed no significant change in physical appearance, drug content, floatability or in vitro dissolution pattern after storage at 45°C/75% RH for three months. The release mechanism was...
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