Posted by admin on Feb 28, 2023 in |
Barringtonia acutangula (L.) Gaertn. (Family: Lecythidaceae), is a medium-sized tree found throughout India. It has been used in folk medicine to treat tuberculosis, skin disease, inflammation, hemorrhoids and diarrhea. The present study deals with in-vitro antioxidant, antimicrobial and GC-MS study on the bark extract of B. acutangula. In order to investigate the antioxidant activity, reducing power activity was used. Antibacterial activity was evaluated by disc diffusion method. Identification of extract bioactive compounds by GC-MS revealed that alpha-Pinene oxide, 1,2-benzoldicarbonsaeure di-(hex-1-en-5-yl-ester), 3-methyl-4-heptanone, (Z)-3-hexadecene are the major components. The antioxidant activity of the bark extract increased with increasing concentration; the values are comparable with the standard antioxidant ascorbic acid. From the results of antibacterial activity, B. acutangula bark extract could inhibit gram-negative and gram-positive pathogenic bacteria. Thus, B. acutangula could be considered as an excellent broad-spectrum antibacterial...
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Posted by admin on Feb 28, 2023 in |
Objective: Cancer being a global threat and deadly disease, necessitate the use of anticancer agents. Hence, continuous drug utilization evaluation studies and Adverse Drug Reaction (ADR) reporting should be carried out in the oncology departments of health care systems. The objective of the study was to identify various types of cancer, assess commonly prescribed anticancer agents using WHO prescribing indicators and report ADRs associated with the anticancer treatment. Materials and Methods: An ambispective observational study was conducted for a period of 6 months in the oncology daycare and in-patient department. All patients receiving at least a single anticancer agent of all age groups of either sex were included in the study. Data was collected in a self-designed patient profile form from the medical records department. Information on drug utilization patterns and ADRs were studied. Results: Breast cancer was the most prevalent cancer observed with more preponderance in females. Paclitaxel was the most commonly used anticancer agent, followed by carboplatin and cisplatin. Granisetron was the widely used adjuvant drug. Only...
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Posted by admin on Feb 28, 2023 in |
The herbal-based formulation “Sugar Care” a product of Miracle Drinks was assessed for an anti-diabetic property on 12 diabetic patients. Each patient was prescribed 15ml of Sugar Care (S10) morning and evening after meal and 15ml of cardiovascular care (S3) in the afternoon. Morning and night doses of sugar care were given along with 15ml of Liver Care (S4) and Renal Care (S5). After 30 days of treatment, the biochemical markers related to blood sugar, like fasting blood sugar (FBS), post-prandial blood sugar (PPBS), and haemoglobin-linked sugar or HBA1C were assessed. A significant reduction of FBS i.e., 50 to 72.2%, was observed in 5/12 diabetic patients. Female patients showed a better recovery rate than male patients, who were 3/4, and 3/8 patients, who showed more than 50% reduction in FBS. A similar recovery trend was also noticed in both male and female diabetic patients that showed a substantial decline in PPBS after treatment with Sugar Care. Three female patients showed substantial change from 346.0±6.0, 420.0±3.0 and 407.3±1.53mg/dl to 158.0±2.0,...
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Posted by admin on Feb 28, 2023 in |
The process of eliminating viral infection and massive control from spreading furthermore by any variants may lead to a pandemic in the near future. On the other aspect, the impact of eradicating by the initial stage to prevent, treat carcinoma to decline the affected and death rate to maximum amount by Molecular Docking. The quickest and easiest method to search out the potential drugs is by analyzing the ligand-protein interactions compared to the traditional ways. Drugs of antivirals and anti-cancer drugs are given for treating viral infections and cancers. Massive kinds of viruses affect humans with several diseases, from self-curable diseases to acute mortal diseases. In cancer, the diseases are known by the cells within humans; multiplication occurs and forming the tumors of malignant cells with the flexibility to be a pathological process. Herbal medicines are known to play enormous role by giving initial priority. Various plant species are being employed to cure or prevent viral infections and cancers. Molecular docking provides a fast understanding of the ligand’s exploration...
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Posted by admin on Feb 28, 2023 in |
Medicinal plants are an abundant source of bioactive compounds, which have been used for thousands of years against different diseases because plants have antibacterial, anti-inflammatory, and antifungal activities. All of the medicinal plants that may be found on earth today have specific therapeutic use and importance. Our research work is based on the qualitative phytochemical studies of extract obtained from leaves of Tinospora cardifolia, Punica granatum, Moringa oleifera, Momordica charantia, Annona squamosa, Eugenia jambolana, and Carica papaya were collected from Bhadravathi taluk of Shivamogga district. These leaf extracts were prepared using various solvents like methanol, acetone, chloroform, and aqueous. Phytochemical screening of these medicinal plants showed the maximum amount of alkaloid, flavonoid, phenol, terpenoid, and tannin in all the extracts. However, methanolic extracts showed good results when compared to other solvent systems. The phytochemical screening of these medicinal plants is commercially very significant and is very important for producing new medication for the treatment of different...
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