Posted by admin on Feb 28, 2023 in |
Azolla is a fern plant through conducting 27 % of protein content and involves actively in bioremediation. So, this property of this plant is exploited in the production of chelated minerals. In this study, selenium-enriched azolla is evaluated with Japanese quails on the performance of growth and serological parameters. The present study is designed with 525 quails divided into 7 treatments, each with 3 replicates. Each replicate contains 25 birds. The evaluation was done from day-old chick to 5-week age in a deep litter farming system. The birds in each treatment are distributed in a randomized manner irrespective of gender, later grouped into control, 0.2, 0.3, and 0.4ppm organic selenium treatments, along with 0.2, 0.3, 0.4ppm inorganic selenium treatments sequentially. The body weight gain, feed intake and feed conversion rate were noted every week and significant changes were recorded. In performance trials we observed that 0.2ppm organic selenium shows good performance in body weight gain (P<0.013) and feed conversion rate (P<0.02) at a significant level. At 0.2ppm concentration of...
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Posted by admin on Feb 28, 2023 in |
Acne vulgaris is one of the most common chronic inflammatory skin diseases affecting more than 85% of adolescents worldwide. Quercetin, curcuminoids, and berberine HCl have anti-acne, anti-inflammatory, antibacterial, and antioxidant characteristics. This study aimed to develop, optimize and evaluate herbal gel containing quercetin, curcuminoids, and berberine HCl. A preliminary trial was conducted for the screening of polymers. A 32 full factorial design was applied to investigate the combined effect of the two independent variables, i.e., the concentration of carbopol 934 and the concentration of propylene glycol, on the dependent variables viscosity and cumulative percent drug release at 8 hrs. The optimized formulation (D0) shows a viscosity of 78123.67±0.69 cps, cumulative percent drug release of quercetin 85.99±1.03%, berberine HCl 35.38± 0.45% and curcuminoids 70.28± 1.18%. An FTIR investigation of drug excipient compatibility revealed no interactions between drugs and excipients. Based on all parameters and experimental design evaluations, it was determined that viscosity increased with increasing carbopol 934 and propylene glycol concentrations; cumulative percent drug release decreased with increasing carbopol 934...
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Posted by admin on Feb 28, 2023 in |
Aegle marmelos, commonly known as Bael or Bilva, belonging to family Rutaceae, has been a tree of humongous significance since time immemorial. It has been used tremendously in ethnomedicine and ethnobotany owing to its spiritual connection. There are testimonials of its prolific use in Ayurveda, Unani and Siddha system of medicine. People also have found this tree of utility owing to its ecological and economic perspective. Almost all the parts of this tree are beneficial and have been used for various reasons. This research was undertaken to ascertain anti-anxiety and antidepressant responses in the hydroalcoholic leaf extract of Aegle marmelos employing the Elevated plus Maze for anxiety and Tail Suspension Test model for depression. Phytochemical screening of the prepared extract was also performed to recognize the phytochemicals possibly accountable for the selective psychotropic activities in the plant. A hydroalcoholic leaf extract using 50% ethanol was prepared and screened for presence of different phytochemicals and was found to comprise alkaloids, carbohydrates, flavonoids, tannins, saponins, terpenoids, coumarins, phenols, and reducing sugars....
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Posted by admin on Feb 28, 2023 in |
Frying is one of the oldest food processing methods. Its popularity is related to the ease and speed of food preparation and sensory characteristics, such as unique flavor and taste. Nowadays, the consumption of deep-fried food has gained popularity which causes an increase risk of different disease conditions such as obesity, cardiovascular disease, diabetes, hypertension, etc. So, the validation and standardization of fried foods commonly used in the household were more important. In this study, the Physiochemical and Organoleptic changes in repeatedly heated different types of oil such as sesame oil, coconut oil, groundnut oil, and refined Sunflower oil for preparing homemade popular South Indian snacks (Muruku) were studied. Density was found to increase gradually in peanut oil and refined sunflower oil. Viscosity was found to be stable in sesame oil. While the viscosity reduces in coconut oil, it increases in refined sunflower oil. The refractive index of the fresh and fried oil was found to be close enough to all the oils except refined sunflower oil, which had...
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Posted by admin on Feb 28, 2023 in |
To study reverse aging in Saccharomyces cerevisiae (S. cerevisiae) by gene expression analysis of target of rapamycin (TOR1) induced autophagy and replicative life span modelling (RLS) using Alpinia galangal (A. galangal), Commiphora mukul (C. mukul), Acorus calamus (A. calamus) and Morshella esculenta (M. esculenta). Methanolic extraction of plants was carried out using maceration. Activation of yeast was performed using the sugar fermentation method. Pharmacological anti-aging screens in yeast performed by RLS. Primers for Actin (ACT1) and TOR1 were designed using Primer-BLAST. Gene expression analysis (RNA isolation and quantification, reverse transcription, and real-time polymerase chain reaction) of TOR1 in S. cerevisiae was conducted using methanolic extracts. Phenolic and Flavonoid compounds were quantified using reversed-phase high-performance liquid chromatography (RP-HPLC). Cell counting and viability assessment of S. cerevisiae with trypan blueusing methanolic extracts was performed. Gene expression analysis results revealed under expression of TOR1 in S. cerevisiae with mean normalized expression ratios < 1 using all four methanolic extracts. Results from RLS showed increased absorbances due to decreased TOR1 activity. HPLC analysis...
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