Posted by admin on Oct 31, 2022 in |
Due to plentiful wild plant diversity, poor road conditions to connect modern medical facilities, and age-old folk knowledge on medicinal plants, the tribal communities of Dhemaji District, Assam, India, still practice traditional plant-based therapy in the management of primary healthcare. The present investigation aims to represent the ethnobotanical knowledge of different ethnic community peoples of the Nilakh- Sripani area, a fringe area laying the Assam- Arunachal border. The ethnobotanical field survey (2018- 2020) was carried out based on formal and informal semi-structured questionnaires with village headmen, traditional healers, and well-educated persons from 11 villages belonging to Nilakh and Sripanigaon panchayat. Analysis of the demographic profile of informants, local names of plants, parts used, used in ailments, preparation and route of administration was investigated during the survey. The documented data were also quantitatively analyzed by using standard ethnobotanical parameters like Use Value (UV), Fidelity Level (FL) and Informant Consensus Factor (ICF). A total of 102 plant species belonging to 57 families were recorded. During the time of the study, 33...
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Posted by admin on Oct 31, 2022 in |
Rett Syndrome is an extremely rare, post-natal, and serious genetic neurodevelopmental syndrome that occurs mostly in female children. It occurs due to the mutations in the MeCP2 gene of the X chromosome. Children with Rett syndrome are usually diagnosed within 24 months of their age. The mutation takes place on the S421 site of the MeCP2 gene. The information for coding MeCP2 protein is obtained from the MeCP2 gene. This protein helps to silence or turn off the other genes. Thus, the mutation of the MeCP2 gene can disrupt the other genes and may interfere with the normal development of the Central Nervous System. The signs and symptoms of Rett syndrome may include slowed growth, brain growth slows after birth, loss of normal movement and coordination, loss of communication abilities, abnormal hand movements, unusual eye movements, breathing problems, irritability, crying, and other abnormal behaviors. There are 3 types of clinical criteria for the diagnosis of Rett syndrome. They are the main criteria, supportive criteria, and exclusion criteria. The doctor...
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Posted by admin on Oct 31, 2022 in |
Quercetin (3, 3ʹ, 4ʹ, 5, 7-pentahydroxyl-flavone) is a flavonol, belonging to the class of plant secondary metabolites known as flavonoids. Quercetin and its derivatives have various beneficial effects against ailments like inflammation, oxidative stress, and cancer. The present research work aimed to prepare and characterize quercetin’s solid dispersion (SD) to enhance solubility and thereby dissolution profile and further incorporate it into oral wafers. The solvent evaporation method was used to prepare solid dispersions using the polymer polyethylene glycol 6000 and pluronic F127. The drug and polymers were compatible, as evident from the FTIR data. The optimized batch was further evaluated by FTIR, DSC, PXRD & SEM. Wafers were prepared by solvent casting method using HPMC (5 & 15 cps), PVA, and plasticizer PEG (200,400) and propylene glycol. Quercitin-loaded SD was added to the polymer solution during casting. Highest drug release of 82.96 ± 1.76 % in 240 min was obtained with a drug to carrier ratio (1:1.5). It followed Higuchi’s model when the amount of solvent was 20 ml....
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Posted by admin on Oct 31, 2022 in |
Background: Acute respiratory infections are the most important cause of mortality and morbidity among under-five children in developed and developing countries in the world. There is lack of awareness/ knowledge among parents regarding antibiotic use in children for minor respiratory ailments. Hence, the present study was undertaken. Methods and Methodology: After taking institutional ethical clearance a Descriptive study on 100 mothers of under-five children attending Urban Health Training Centre of KIMS, Bangalore, is enrolled by convenience sampling. Using pre-structured and pre-tested questionnaire proforma, socio-demographic details, a few questions related to acute respiratory infections were collected. After the pre-test, health education was given to the urban health training center participants using flip charts. Followed by 2 weeks of health education, the same questionnaire was given to the subjects, and details were collected. Descriptive statistics and SPSS V20 were used for statistical analysis. Results: Pre and post-test knowledge and attitude were analyzed using wilxcon sign rank test, which showed the effect of health education was found to be statistically significant with...
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Posted by admin on Oct 31, 2022 in |
N. nucifera, often recognized as lotus, is an aquatic plant. Extracts of various solvents have shown therapeutic potential against many diseases. This research focused on screening preliminary qualitative phytochemicals and investigating the seed’s antioxidant activity. Primary and secondary metabolites were discovered in a hydroethanolic fraction of different extracts of lotus seeds. The extractive value, total ash (3.56±0.36) water-soluble (0.86±0.68), and acid insoluble ash value (2.09±0.88) were determined. The solvents benzene, chloroform, ethyl acetate, n-butanol, and aqueous were used as extracts. TPC and TFC content of ethyl acetate extract of seeds were found to be 366.6±10.77 (mg GAE/ g-1 dry weight) and 344.4±3.71 (mg RE/ g-1 dry weight), respectively. The ethyl acetate fraction of the seed extract showed the lowest value determining the highest free radical scavenging activity (105.30 ± 12.06µg/ml) in DPPH and FRAP (142.2± 0.0509 mgAA gm-1). The values were found to be close as compared to the standard (56.40±23.63µg/ml).The results support high antioxidant content in the seed extract of N. nucifera. FTIR and GCMS did the characterization...
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