Posted by admin on May 31, 2022 in |
Aim of study: A Randomized controlled trial was planned to evaluate the Clinical efficacy of Nidigdhikadileha an Ayurveda multi-dimensional herb preparation in children suffering from Recurrent Respiratory tract infection in children. Nidigdhikadileha contains Nidigdhika (Solanum Xanthocarpum), Pippali (Piper longum), Amrita (Tinospora cardifolia), and Nagar (Zingiber officinale). All these drugs have been described to have anti-tussive and antimicrobial properties. Material & methods: A total of 90 children, including male and female children, were studied for complaining of Recurrent Upper Respiratory Tract infections and were registered and divided into 3 groups (Group A, B, C). In group A, children were administered Nidigdhikadileha, dose180-200 mg/kg/dose twice a day for 2 months in children suffering from RURTI. In group B, honey drops were administered to 30 children at a dose of 1ml/kg/day, and in Group C there is also 30 patients were administered Sitopaladi churna at a dose 100 mg/kg/day. All the treated cases were assessed at each follow-up on the 14th day, 28th day, 42nd day, and 56th day, and post-follow-up was...
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Posted by admin on May 31, 2022 in |
Urochloa distachya (Poaceae), commonly known as Signal grass 20-60 cm long found in tropical Asian origin, Africa, and other countries. Generally, it has been used in fodder, animal feed etc., and least and no therapeutic activities were reported. The present study was established to identify the phytochemicals by using GC-MS of the U. distachya leaves part. The leaves part of the plant was extracted in methanol by using the Soxhlet apparatus. The GC-MS Methanolic extract of U. distachya identified 26 phytocomponents; Z-7-Pentadecenol; t-Butyl hydrogen phthalate, Ricinoleic acid; Methyl -12-hydroxy-9-octadecenoate; Octadecanoic acid; Glycerin; 4, 6-Diphenyl-2-(2-hydroxyphenyl) pyrimidine, Eicosanoid acid, methyl ester, 2-Naphthalenol 2, 3, 4, 4a, 5, 6, 7-octahydro1, 4adimethyl-7-(2-hydroxy-1-methylethyl); Cholest-5-en-3-ol (3á), tetradecanoate; 6-Octadecenoic Acid; Oleic acid, 3-hydroxypropyl ester; Octadecanoic acid, 2, 3-dihydroxypropyl ester; Eicosane; Tert-Hexadecanethiol; 2-[4-methyl-6-(2, 6, 6-trimethylcyclohex-1-enyl) hexa-1, 3, 5-trienyl] cyclohex1en-1-carboxaldehyde; Spiro [4.5] decan-7-one, 1, 8-dimethyl-8, 9-epoxy-4-isopropyl; 9, 12, 15-Octadecatrienoic acid, 2, 3-bis [(trimethylsilyl) oxy] propyl ester, (Z, Z, Z). The phytoconstituents of methanolic extract of U. distachya has shown remarkable activities like antimicrobial, antioxidant, anti-inflammatory and anticancer...
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Posted by admin on May 31, 2022 in |
Background: Hypothyroidism is a metabolic disorder. Vitamin D is known to improve the impact of autoimmune diseases; hence, vitamin D supplements and adjuvant therapy can improve hormonal and metabolic imbalance along with oxidative stress. The study aims to determine the effect of Vitamin D on the oxidative stress parameter in hypothyroid patients compared to controls and hypothyroid subjects before and after vitamin D therapy. Methods: A prospective study of six months period was carried out among 120 subjects attending the General Medicine department. Age and gender-matched euthyroid controls (n=40) and patients who were newly diagnosed as hypothyroid (with increased serum TSH and or with decreased serum T3 or T4levels) were taken as cases (n=80). Serum TSH (mµ/L), T3(pg/m), and T4(ng/dl) levels were compared. Oxidative stress parameter (MDA) in hypothyroid patients is a tool to assess oxidative stress levels it was measured by using the Immunoassay method. Results: Oxidative stress parameter (MDA) in hypothyroid with and without vitamin D supplementation showed improvement indicating decreased levels in oxidative stress, along with statistical...
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Posted by admin on May 31, 2022 in |
An ethnomedicinal exploration of weeds of Jhansi district, located in the state of Uttar Pradesh in India, has been carried out to identify and find out the use of weeds to treat different ailments. Folklore people living in remote areas do not have easy access to hospitals or medical facilities, so they depend on the plants and weeds present in their surroundings to treat various diseases or physical ailments. A survey was made to get the knowledge of medicinal values of weeds in three regions of Jhansi, and it was found that a total of 30 weeds was used at most by folklore people for their treatments. Identified weeds belonging to families Malvaceae, Asteraceae, Solanaceae, Euphorbiaceae, Poaceae, Amaranthaceae, Convolvulaceae, and Ceasalpinaceae, etc. were found to treat various ailments like fever, cough, flu, nausea, skin diseases, body ache, and overall weeds were also known to increase the immunity of the body. Although there is literature known about the uses of weeds or other plants, it is still required more to...
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Posted by admin on Apr 30, 2022 in |
Context: Ayurveda emphasizes applying herbal, metallic, mineral, and herbo-mineral preparations in therapeutics. Trivanga Bhasma (TB) is a potential trimetallic (Tin, Lead & Zinc) compound formulation widely used in routine Ayurvedic practice to treat several chronic ailments. Objective: To elucidate the toxicity profile of TB by oral administration in wistar albino rats to ascertain the safety aspects. Method: TB was administered in possible higher doses such as TED (Therapeutic Equivalent Dose), TED × 2 (2 times the Therapeutic Equivalent Dose), TED × 5 (5 times the Therapeutic Equivalent Dose) and TED × 10 (10 times the Therapeutic Equivalent Dose) for 28 days. The effect was assessed on ponderal changes, biochemical parameters, histopathology, and tissue analysis. Results: Results showed that TB did not induce any toxicity at TED, TED × 2, TED × 5; whereas histopathology and tissue analysis of very higher dose TED × 10 exhibited toxicity in the liver & kidney. Conclusion: The drug, however, at a dose of TEDx10 showed mild undesirable changes in the liver & kidney;...
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