Posted by admin on Apr 30, 2025 in |
In an increasingly fast-paced world, the rising prevalence of anxiety and mental health disorders highlights the critical need to preserve cognitive well-being. While mental illnesses often result from complex biological, psychological, and environmental interactions, their precise origins remain elusive. Conventional medicine offers various treatments, but alternative approaches, like nervine tonics, are garnering attention for their natural, therapeutic potential in supporting the nervous system and promoting relaxation. This study introduces Neuragreen, a novel polyherbal nervine tonic designed to enhance blood circulation, regenerate nerve cells, and exhibit potent nootropic, anti-Alzheimer, anti-depressant, and antioxidant effects. The formulation blends powerful herbal ingredients, including Ginkgo biloba, Centella asiatica, Bacopa monnieri, Withania somnifera, Mucuna pruriens, Pueraria tuberosa, Convolvulus pluricaulis, Celastrus paniculatus, Beta carotene, and B-complex vitamins. A multidisciplinary approach was employed, utilizing LCMS, UV-Visible, and FTIR spectroscopy, along with antioxidant assays and molecular docking. LCMS identified diverse bioactive compounds, while UV-Visible spectroscopy revealed the presence of flavonoids, terpenes, and alkaloids. FTIR confirmed the presence of polyphenolic compounds with antioxidant potential, and terpenoids were also detected....
Read More
Posted by admin on Apr 30, 2025 in |
Background: Cerebrovascular Accident (CVA) ranks as the third leading cause of mortality globally and contributes significantly to chronic adult disabilities. Hemiparesis, the most prevalent post-stroke mobility impairment, affects approximately 75% of stroke survivors, substantially reducing their quality of life. This study aims to investigate CVA-associated Hemiparesis and Hemiplegia, focusing on management strategies to improve functional outcomes. Methods: A prospective observational study was conducted over six months include CVA patients aged > 30 years with CVA associated Hemiparesis or Hemiplegia, comprising both hospitalized and follow-up outpatient cases. Data were collected from patient case records and structured questionnaires, covering demographic details, type of stroke, drug therapy, type of physiotherapy received, adherence to post-discharge physiotherapy, and its impact on recovery. After completion of the study, the data were systematically analyzed and results were interpreted. Results: Hypertension was identified as the most common risk factor (39%), and statins were the most frequently prescribed pharmacological treatment (31%). Constraint-induced movement Therapy (CIMT) was implemented in 54% of cases, and regular post-discharge physiotherapy was undertaken by...
Read More
Posted by admin on Apr 30, 2025 in |
Medicinal plants play pivotal roles in novel drug discovery or combinatorial drug surveillance against emerging infectious diseases. This study aims to explore and compare the bactericidal and antibiotic modulating activities of stem barks of Gmelina arborea Roxb. and Oroxylum indicum (L.) Kurz against two pathogenic bacterial strains, i.e., Escherichia coli and Staphylococcus aureus. Methanolic stem bark extracts of G. arborea and O. indicum were subjected to phytochemical analysis, DPPH antioxidant assay, and varieties of antibacterial assays (disc diffusion, agar well diffusion, modified agar well diffusion, and bacterial cell viability), and the results were compared. Phytochemical analysis revealed that both plants had major bioactive compounds like alkaloids, terpenoids, phenol & tannins, steroids, glycosides, etc. G. arborea had a total phenol content (TPC) of 27.33±8.60 mg/g of Gallic Acid Equivalent (GAE) and a total flavonoid content (TFC) of 72.33±4.90mg/g of Rutin Equivalent (RE). At the same time, O. Indicum was calculated to have a TPC of 48.58±1.80 mg/g of GAE and TFC of 269±0.88mg/g of RE. Though both stem barks exhibited...
Read More
Posted by admin on Apr 30, 2025 in |
Water is an essential ingredient for all living things to exist on earth. Ancient Siddha texts suggest that soaking some therapeutic plants may purify water. The current study aims to assess the water quality after being soaked with Terminalia chebula (Kadukkai) and Terminalia bellerica (Thantrikkai). Three distinct pots containing two liters of drinking water each were taken from Chembaramapakkam Lake and designated as samples A, B, and C. As a control group, Sample A was left behind. In the same setting, 50g of Terminalia chebula is soaked for 6 hours in the sample B container, and 50g of Terminalia bellerica is soaked for 6 hours in the sample C container. All filtered samples were then subjected to elemental analysis, microbiological testing, and physical inspection as per the drinking water standard methodology. The water treated with Terminalia chebula and Terminalia bellerica had improved color, odor, pH, hardness, alkalinity, and conductivity within allowable bounds. Elemental analysis showed elevated calcium levels, NO2 below the detection limit, and Cl, SO4, and Fe within...
Read More
Posted by admin on Apr 30, 2025 in |
The research rigorously investigates the bioactive potential of Cynodon dactylon, specifically focusing on its antipyretic properties attributed to quercetin, a flavonoid compound. Cynodon dactylon, a perennial grass, has been traditionally used in various medicinal practices, prompting scientific inquiry into its pharmacological benefits. The study involved meticulous extraction and isolation of quercetin from Cynodon dactylon using advanced solvent extraction and chromatographic techniques. The purity and structure of the isolated compound were unequivocally confirmed through rigorous spectroscopic methods, including UV and NMR analyses, ensuring the absolute reliability of the isolated quercetin for subsequent pharmacological evaluations. An in vivo experimental model using pyrexia-induced rodents was employed to robustly assess the antipyretic activity of Cynodon dactylon extract and isolated quercetin, comparing their efficacy with standard antipyretic drugs. The results unequivocally indicated a significant reduction in elevated body temperature in the treated groups, conclusively demonstrating the remarkable effectiveness of Cynodon dactylon and its quercetin component in reducing fever. The study concludes that quercetin isolated from Cynodon dactylon exhibits notable antipyretic activity, unequivocally validating its...
Read More
