Posted by admin on Feb 28, 2025 in |
Giving birth is the most physically exhausting experience for a woman’s body. Tribal societies use medicinal plants and nutrient-dense foods as natural remedies to boost vitality, facilitate healing, and increase milk supply after delivery of women. The present study was carried outinthetribal-dominated areas of southern Rajasthan, including Banswara, Chittorgarh, Dungarpur, Pratapgarh, Udaipur, and certain parts of Sirohi District. During the study, group discussions and interviews were done with the active participation of local women, health practitioners, and elders known as dais or gunis, who are experts in delivering traditional health care services to lactating mothers in the research area. In the present study, 11 plant species from 9 families were reported as being used to boost milk production and support postpartum recovery by tribal women. The study revealed significant and vital information on the diversity of medicinal plants used by various traditional practitioners in postnatal care, which can be further integrated into the modern healthcare system to improve the health status of lactating women...
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Posted by admin on Feb 28, 2025 in |
Cadmium (Cd) is the seventh most toxic heavy metal; a potentially hazardous metal found that has a substantial impact on the peripheral (PNS) and central nervous systems (CNS). This study is aimed at investigating the concommitant administration of ethanol leaf extract of Anacardium occidentale (AO) and ripe Musa sapientum (MS) peels on fine motor functions in Cd-induced neurotoxicity in female wistar rats through. 30 adult female wistar rats (75 – 154 g) were used for this study. They were divided randomly into six groups (n=5). Group 1 (Control) received 1mL of distilled water. Group 2, 3,4 and 5 were treated with 100 mg/kg of Cd, 2.5 mg/kg of Donepezil, 200 mg/kg AO and 200 mg/kg MS respectively. Group 6 was co-treated with 200 mg/kg of AO and 200 mg/kg of MS for 21 days. Animals were then subjected to Neurobehavioural experiment using wire hang test for assessment of muscular strength. Biochemical assay for the assessment of Interleukin-6 (IL-6) and histological analysis of the cerebellum was done. The result of...
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Posted by admin on Feb 28, 2025 in |
This study focuses on developing and characterizing metformin microspheres using spray drying with hydroxypropyl methylcellulose (HPMC) as a polymer, aiming to enhance gastrointestinal drug delivery, reduce gastric irritation, and lower dosage requirements for type 2 diabetes management. Metformin hydrochloride and HPMC concentrations are varied to generate microspheres with1 to1000µm diameter. These biodegradable polymers were selected because of their efficacy and compatibility with drugs. The thermal analysis and compatibility of the excipients used in microsphere tablet compression are assessed using differential scanning calorimetry and Fourier transform infrared spectroscopy. In-vitro drug release behaviour is evaluated over an 8-hour period using a Copley dissolution tester in 0.1 N HCl at 37 ± 0.5°C, with drug release monitored by UV spectroscopy at 228 nm. Results show that metformin release from microspheres is sustained for the first 6 hours, with a decrease noted at the 8-hour mark. The Higuchi model suggested diffusion-controlled release, while the Korsmeyer-Peppas model indicated non-Fickian diffusion. Some other drug release kinetic models, such as zero-order and first-order kinetic models are...
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Posted by admin on Feb 28, 2025 in |
Background: Diabetes is one of the leading non communicable disease-causing various health complications like Cerebrovascular accidents, micro and macrovascular complications. In Indian population, very few comparison studies have been conducted to evaluate the glucose lowering effect of omega 3 fatty acid between diabetic and non- diabetic dyslipidemic patients. Hence the present study was planned to compare the efficacy of omega 3 fatty acid among diabetic and non-diabetic dyslipemic individuals. Materials And Methods: This study is a comparative, randomized, open-label, prospective interventional study which compared the efficacy of omega 3 fatty acids as add on therapy among diabetic and non-diabetic Dyslipidemic patients.50 Patients of 25 each of diabetic dyslipidemia and non-diabetic dyslipidemia attending the out-patient department of Internal Medicine, Rajiv Gandhi Government General Hospital, Chennai were given 1 gram of omega 3 fatty acid- fish oil capsule per day once daily to take orally for 8 weeks and monitored for random blood glucose at baseline (0 weeks), after 4 weeks and after 8 weeks of treatment. Results: At 4 weeks...
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Posted by admin on Feb 28, 2025 in |
Objectives: Transitioning from a family-centred clinic to a patient-centred clinic is an inevitable and fragile process through which patients and caregivers have to go through. This study aimed to identify transition issues and assess the role of pharmacists during this phase. Method: A mixed-method approach combining qualitative and quantitative analysis was used to identify factors that may contribute to uncontrolled diabetes during the transition period. Due to the challenges posed by the COVID-19 pandemic, three online questionnaires were developed, reviewed, and distributed via social media to patients, caregivers, and healthcare professionals. Key Findings: Concerns were raised about being under the care of a new doctor and not being provided enough support and care during the transition. Participants noticed a shift towards self-management as they moved between clinics. Furthermore, there was strong support for the involvement of pharmacists in the transition process, with participants agreeing that pharmacists could help reduce medication errors. Conclusion: A well-structured transition plan can ease the shift from paediatric to adult care. A multidisciplinary approach, involving...
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