Posted by admin on Oct 31, 2024 in |
Background: Epilepsy is a common neurological disorder which results in significant morbidity. Epilepsy accounts for a significant proportion of the world’s disease burden, affecting around 50 million people worldwide. Aims: In this study, evaluate anti-epileptic drug for seizure control in Emergency room and effectiveness of various anti-epileptic drugs in terms of time to Seizure control. To assess the treatment satisfaction measured using the Treatment Satisfaction with Medicines Questionnaire (SATMED-Q). Materials & Methods: A Prospective observational study of 18 months duration carried out in patients presenting with seizure at Emergency department during the study period. The study began after the approval of study protocol by the Institutional Review Board. Statistical analysis was done using Microsoft Excel Office 2019 and rechecked with SPSS (version 25.0). P value <0.05 was considered as statistically significant. Result: Total 121 patients presented with seizure in Emergency, were recruited in the study during study period. About 98 patients completed the study and 23 were lost to follow-up. Out of 121 patients 80 (66%) were males and...
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Posted by admin on Oct 31, 2024 in |
Spinal anaesthesia is most frequently used for transurethral prostatectomy (TURP), because it permits early recognition of TURP syndrome. However, many elderly patients can have coexisting cardiac or pulmonary disease so, it is important to limit the distribution of spinal block in such patients. Aim and Objectives: To evaluate the efficacy and effect of addition of fentanyl 25 μg (0.5 ml) intrathecally to bupivacaine 5mg (0.5%) (1ml) and low dose bupivacaine 7.5mg (0.5%) (1.5 ml) alone for TURP. Methodology: It was a comparative prospective study under which 60 subjects were enrolled and divided into 2 groups of 30 patients each. Group A will receive Low dose bupivacaine 7.5mg (0.5%) (1.5 ml) Group B will receive bupivacaine 5mg (0.5%) (1ml) and fentanyl 25 μg (0.5). Results: Sensory block duration is higher in group B patients while time of onset of sensory block is low in Group B patients (1.18 + 0.31) in compare to Group A (1.59 + 0.34), similar findings were observed for motor block. In Group A complications of...
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Posted by admin on Oct 31, 2024 in |
Urtica dioica L. and Urtica dioica L. angustifolia are commercialized as the same plant under the name stinging nettles (Ortiga) but, to our knowledge, the antibacterial properties of the variety angustifolia are unknown. The antibacterial activity of Urtica dioica L., collected in the State of Mexico, was compared with that of Urtica dioica L. variety angustifolia, acquired in a market in Mexico City. The extracts were obtained by consecutive maceration of leaves in hexane, dichloromethane, methanol, and water for 48 h, dilutions of 5-0.03 mg/mL of each were added to culture plates with 4 x 106 Colony-forming units (CFU)/mL, resazurin, and Müeller-Hinton medium 3X. The cultures were incubated for 22 h/37°C. The bacteria employed were as follows: Salmonella typhimurium, Shigella flexneri, Salmonella typhi, Proteus mirabilis, Escherichia coli, Bacillus subtilis, and Staphylococcus aureus. Each extract was evaluated on three occasions in triplicate. 1% Dimethyl sulfoxide (DMSO) and a solution of Penicillin-Streptomycin were used as negative and positive control, respectively. In terms of Urtica dioica L., the hexanic and dichloromethanic extracts...
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Posted by admin on Oct 31, 2024 in |
Cosmetics have been in high demand since ancient times until today. Lipsticks are a type of cosmetic used to enhance their appearance and protect the lips. Generally, waxes, oils, emollients, pigments, and varieties of dye or colouring agents are used to prepare lipsticks. Synthetic colours and other ingredients are hazardous to the human skin and body. Substituting synthetic ingredients with natural substances will decrease the side effects of lipsticks. Also, natural ingredients protect lips from cracking and drying out, etc. With this objective, a study was performed to formulate lipsticks using natural colour extracted from leaves of Amaranthus gangeticus L. It is a popular leafy vegetable in north-east India, and it possesses different pharmacological activities. The phytochemical screening of the extract showed the presence of alkaloids, glycosides, and tannins, which increase the nutritional value of the herb. A total of six formulations were prepared with different concentrations of colour extract and evaluated with parameters such as melting point, breaking point, spreadability, surface anomalies, stability, irritation test, etc. The formulations...
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Posted by admin on Oct 31, 2024 in |
Aim: The aim of the present study was to compare the efficacy of two different doses of labetalol for controlling these hemodynamic responses to laryngoscopy and tracheal intubation in controlled hypertensive patients. Material and Methods: Present study conducted on 90 patients posted for various elective surgeries under general anesthesia at our institute. Study populations were randomly divided into 3 groups. Group L1: Received Inj Labetalol 0.15 mg/kg iv 5 min before intubation, Group L2: Received Inj. Labetalol 0.3 mg/kg iv 5 min before intubation and Group C: Received 0.9% normal saline iv 5 min before intubation. Heart rate (HR), systolic blood pressure (SBP) and diastolic blood pressure (DBP) were recorded prior to induction, at time of intubation and various intervals after intubation. Results: The control in HR, SBP, DBP, MAP and RPP was statistically significant between Group L1 and Group L2 at 3 min, 5 min post intubation. There was significant difference in HR throughout study time between L1 C and L2 C. Conclusion: Labetalol in both doses is...
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