Posted by admin on Aug 31, 2020 in |
Bastar is endowed with a unique blend of traditional knowledge and rich floral diversity. The region is known as the island of Shorea robusta, which is a key source for white and black truffle called Boda. It is also known as the black gold of the sal forest. It sets underground with the onset of early monsoon and is an edible mushroom with high protein, vitamin, and fiber with the low calorific value used by the local inhabitants as delicious food and in the amelioration of heart disease, blood pressure, and stomach disorder. Owing to its tremendous health benefits, the present study deals with the assessment of the protein content, isolation, and identification of fungi associated with boda. The qualitative analysis revealed that black boda contains more protein content than white boda. The quantitative estimation revealed the presence of 0.97 mg/ml and 0.33 mg/ml of protein for 0.2 mg weight of black and white boda, respectively. Further, the boda sample were inoculated on potato dextrose agar and incubated at...
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Posted by admin on Aug 31, 2020 in |
Medicinal plants abound with many phytochemicals that are effective in representing lots of pharmacological activities. The current study aimed at investigating the phytochemical and pharmaco-logical activity of crude methanol extract of Calamus rotang L. (CRME) leaves. The analgesic activity and thrombolytic activity were examined by the acetic acid-induced writhing method, while the clot lysis effect was evaluated by an in-vitro thrombolytic method. From this study, it is stated that the extract (400, 200 mg/kg) reduced abdominal writhing by 31.06% and 44.33% for 200 mg/kg and 400 mg/kg respectively while the standard showed 58.57% of inhibition and increased the pain reaction time in mice when compared to that of the negative control group in tail-immersion test. The extract presented 16.2 ± 1.75% of human blood clot lysis in the thrombolytic experiment. The presence of steroids, saponins, glycosides, cardenolides, flavonoids, carbohydrates, and reducing sugars might have an influence on the pharmacological activity of...
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Posted by admin on Aug 31, 2020 in |
The new asymmetrical tetradentate (ONNO) Schiff base (L) 4-chloro- 2- ((E)- (4- ((E)-((2-hydroxy-5-nitrophenyl)imino)methyl)benzylidene) amino)phenol was prepared by the condensation of terephthalaldehyde with 2-amino 4-chlorophenol and 2-amino 4-nitrophenol in 1:1:1 molar ratio in methanol. The homo binuclear metal(II) complexes were synthesized in ligand to metal ratio 2:2 from the template method. The composition, geometry and binding sites of ligand and its complexes were determined by various studies like Elemental, molar conductance, electronic, magnetic moment, FT-IR, 1H and 13C-NMR, ESI-Mass, EPR, Thermal, and PXRD. The above spectral studies show that the Schiff is a dibasic tetradentate (ONNO), and its metal complexes possess a square planar structure. The biological applications of all compounds were tested for antibacterial, antioxidant, and DNA cleavage, and the final reports reveal high inhibition activity for metal(II) complexes compared to the ligand. The DNA binding activities of Cu(II) complex was observed by electronic absorption method. Antitumor activity of Cu(II) complex was screened for their cancer-inhibiting ability against MCF-7 human breast cancer cells by using the MTT...
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Posted by admin on Aug 31, 2020 in |
Increase in industrialization has raised the levels of heavy metal pollution in the country. In order to combat with this problem, many strategies were developed till date, and among them, the use of microorganisms is the most successful technique. The present study was undertaken for isolation, identification, and characterization of heavy metal (Cd) tolerant bacteria from industrial effluents of electroplating, steel and battery industry SAS Nagar, Punjab and Chandigarh (India). The effluents were initially tested for physicochemical parameters (BOD, COD, TDS, TSS, etc.).The cadmium content was quantified through spectrophotometric assay. Initially, a total of 20 bacterial isolates were isolated and screened, then the effect of selected strain on all the parameters of test samples was checked. On the basis of performance to cadmium tolerance, only two isolates were selected. These bacteria could tolerate cadmium up to 1000 ppm and 1500ppm. These isolated bacteria may be helpful for the bioremediation of heavy metal contaminated industrial...
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Posted by admin on Aug 31, 2020 in |
Dry Eye Syndrome is a common disorder of the normal tear film that results from one of the following: decreased tear production, excessive tear evaporation, an abnormality in the production of mucus or lipids normally found in the tear layer. Carboxymethylcellulose (CMC) is a highly viscous derivative of cellulose that is used as an eye lubricant. CMC moistens the eye to prevent or relieve dry eye and irritation. Emulgels are nothing but emulsions that may be of water-in-oil or oil-in-water type, which, when blended with gelling agents, gets jellified. Emulgels are a slight viscous product that creates the strength of the product to enhance the retention on eye and improve the spreadability of the product. Castor oil and CMC based emulgel were prepared in three different phases like Polymeric Phase (CMC and Carbomer), Oil Phase (Castor oil), and Aqueous Phase (excipient phase). Process variables also identified and design space created by varies the concentration of oil, surfactant, and polymer. Different formulations designed with changes in oil concentration from 0.25%...
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