Posted by admin on Dec 31, 2024 in |
Background: Globally used modern medicines cause various adverse drug reactions (ADR). In order to improve patient safety and welfare, and to reduce patient morbidity and mortality, spontaneous ADR reporting is the need of the hour. Nurses are the first point of contact with patients in any hospital, so their awareness is important to improve the practice of pharmacovigilance. Objectives: To assess the knowledge, attitude, practice and impact of an educational intervention on pharmacovigilance among nurses. Methodology: A cross-sectional observational study done among 86 Nursing officers, employed at a tertiary care teaching hospital in southern Rajasthan. After taking consent, a pre-validated questionnaire comprising of four sections: demographic data, questions to evaluate knowledge, attitude and practice towards pharmacovigilance and ADR forms were provided to the participants and a pre-test was conducted. This was followed by a well-planned overview of Pharmacovigilance Programme of India (PvPI), case-based training session and a post-test. Result: The calculated mean score of questions regarding knowledge, of Pre-test was 2.88 and Post-test was 6.05 out of 8, which...
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Posted by admin on Dec 31, 2024 in |
Rhodamine-based Schiff bases are interesting functional materials because of their bright color, durability, and biomedical uses. The aim of this study was to synthesize and characterize the novel Rhodamine-based Schiff base (RSB) to investigate their structural characteristics. The synthesized dyes were characterized via FTIR, ¹H NMR and ¹³C NMR to ensure their structural integrity and purity. This approach has many appealing advantages, including excellent yields, quick reaction times, and easy...
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Posted by admin on Dec 31, 2024 in |
Background: The rapid development of new technology, and especially the Internet and other related communication systems, has provided new possibilities for searching any information that can be used for self-medication, also it seems that medical students having proper knowledge of medicine are very much involve in self-medication. This study therefore, intended to evaluate the knowledge, attitude, practice, and associated factors on SM among the medical students at government medical college, Almora. Methods: A cross sectional study was conducted on the students of phase II and phase 3 part I in the government medical college, Almora from 27th May 2024 to 7th June 2024. The data was collected through questionnaire circulated to concerned batch students via Google link. Results: A total 197 students were enrolled in the study, out of them, 101 were males while 96 were females. It was found that 78.7% of them, utilised self-medication in past 6 month. It was found that they had good knowledge regarding self- medication and its adverse effect. It was found that...
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Posted by admin on Dec 31, 2024 in |
Parasitic worms live in and feed in living hosts. They receive nourishment and protection while disrupting their hosts ability to absorb nutrients. The macroparasites called helminths, causes Helminthiasis. In India, the overall prevalence rates range from 12.5% to 66%. About 50% of the urban population and 68% of the rural population in India is affected. According to WHO, just few medications are consistently utilized for the treatment of these parasite diseases, these include albendazole, mebendazole, piperazine thiabendazole and levamisole. The resistance of helminths to drugs poses health complications to both man and animals which increased the demand for the use of herbal drugs. The present study was carried out to evaluate anthelmintic activity of leaves of Trachyspermum ammi and Desmodium gangeticum. Earthworms (Eisenia fetida) were chosen for studying anthelmintic activity as they have resemblance to intestinal round worms. The earthworms were exposed to series of concentrations 100mg/ml, 200mg/ml, 300mg/ml, 500mg/ml, 1000mg/ml of leaf extracts. Albendazole is used as a standard drug. Results revealed that a dose dependent decrease of paralysis time and death...
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Posted by admin on Dec 31, 2024 in |
The biological effects of transition metal complexes that include a wide range of ligands are distinguishable from one another. In an effort to produce a novel metal (II) complexes the conventional reflux method has been used to the interaction of two ligands, N-(2H-benzo[d] [1,2,3] triazol-2-yl)-1-(4-nitrophenyl) ethanimine as L1 and an amino acid Alanine as L2 with freshly produced Zinc, Nickel, Manganese chloride’s solution in a 1:1:1 molar ratio. In order to characterize the ligand and metal (II) complexes that have been synthesized, several approaches such as elemental analysis, molecular weight analysis, thermal analysis and spectroscopic analysis are used. A comparison was made between the antibacterial activity of all of the compounds that were created and that of Streptomycin, Ciprofloxacin and Nystatin. The compounds were tested against Gram-positive and Gram-negative bacteria as well as a variety of fungal strains. The insecticidal activity of each compound was evaluated against Plodia interpunctella and the findings revealed that the compounds exhibited promising...
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