Posted by admin on Jan 31, 2020 in |
The drug Parpataka is used particularly for the treatment of fevers, indigestion, biliousness, burning of the body, tired feeling, giddiness, urinary discharges, vomiting, thirst, enriches the blood and works good in leprosy. The present study is intended to authenticate and validate the species of Peristrophe paniculata (Forssk.) Brummitt, which is one of the sources of the Parpataka drug used in Ayurvedic and Siddha systems. The objective of the present work was to assess and established the various pharmacognostical properties like; macroscopical, micro-scopical (cell structure and their arrangement), physicochemical (including different ash values, loss on drying and extractive values), fluorescence and preliminary phytochemical profiles of the leaf, stem and roots of the plant. Qualitative tests for various functional groups were also carried out. The pharmacognostical screening of Peristrophe paniculata on different standardization parameters may prove to be very useful for the correct identification of the genuine drug and also to determine the quality and purity of the plant material to be used in different Ayurvedic...
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Posted by admin on Jan 31, 2020 in |
Objective: The purpose of the study is to pursue some heavy metals in the aqueous environment of Tigris river that passes through Mosul city prior to the bioaccumulation of such metals in catfish Silurus glanis and its intestinal tapeworm Postgangesia armata. Methods: Silurus glanis, a freshwater fish were hunted from Tigris river passing through Al-Rashidiya region/Nineveh Governorate, North Iraq, during November 2017 and May 2018. Bioaccumulation of Fe, Cr, and Mn were estimated in different body tissues of infected and uninfected catfish, and in catfish intestinal tapeworm P. armata. Atomic absorption Spectrophotometer was used to estimate heavy metal concentration as µg of a particular metal/gm of fresh weight. Results: Concentration of the metals in catfish tissues were in the order of Mn > Fe > Cr. Whereas, concentration of the metals of the tapeworm P. armata were in the order: Fe > Mn > Cr. Moreover, mean concentrations of the three heavy metals (Cr; Fe and Mn) were lesser in body tissues of infected catfish than in the uninfected...
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Posted by admin on Jan 31, 2020 in |
Alangium salvifolium is a plant that is traditionally used to treat many diseases like laxative, antiepileptic, jaundice, antiulcer agent, agent to alleviate spasms, anthelmintic, emetic, antiprotozoal agent and hypoglycemic agent. Its subspecies Alangium salvifolium subsp. Hexapetalum (Wangerin) is also known for a variety of traditional use like hemorrhoids, rheumatism, and antidote for snake bite. The present work aims for the evaluation of the in-vitro and in-vivo anti-diabetic activity of methanolic extract of aerial parts of Alangium salvifolium subsp. Hexapetalum (Wangerin). The in-vitro antidiabetic activity was evaluated by a starch-iodine color assay method. The in-vivo method was performed by administering orally the methanolic extract of Alangium salvifolium subsp. Hexapetalum in streptozotocin-induced male Albino Wistar rats weighing 200 g. The study was compared using standard metformin hydrochloride (10 mg/kg body weight). The in-vitro method showed a dose-dependent anti-diabetic activity that is as the dose increases the percentage inhibition of enzyme activity also increases. The in-vivo anti-diabetic activity was accessed by comparing the body weight and blood glucose level on 0th, 5th, 10th...
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Posted by admin on Jan 31, 2020 in |
In this study attempt has been made to develop the monographic parameters for Ficus glomerata Rox. leaves were collected from Gangetic plains (Lucknow). Under the study, pharmacognostic parameters were performed including macroscopic characters, microscopic characters, physicochemical parameters (extractive values, ash values, pH analysis, LOD), and preliminary phytochemical screening. Apart from pharmacognostic and phytochemical screening, HPTLC fingerprinting profile was also developed for F. glomerata Rox. Leaf extract. Pharmacologically active secondary metabolites like polyphenols and flavonoids were determined by using methods of phenolic content assay and total flavonoid content assay respectively. Leaf powder of F. glomerata was subjected to successive extraction with petroleum ether, chloroform, methanol and water. Different extracts were utilized for different parameters as per the requirement of...
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Posted by admin on Jan 31, 2020 in |
Aegle marmelos commonly known as Bael has been widely used traditionally due to its various medicinal properties. Cyclophosphamide is an alkylating agent used in the treatment of various types of cancer by slowing or stopping the growth of cancer cells but also affecting the normal cells leading to immunosuppressant effect. The present study has been aimed to see the protective effect of hydroalcoholic extract of Aegle marmelos fruit (AME) in normal and immunosuppressed rats. Different doses of AME i.e. 100, 250 and 500 mg/kg were administered orally for 14 days. On 15th day cyclophosphamide was given at a dose of 180 mg/kg subcutaneously. On the 18th day, hematological parameters like red blood cells (RBC), white blood cells (WBC), platelets, and neutrophil adhesion assay were carried out. AME showed a significant increase in white blood cell count, neutrophil count, eosinophil count, lymphocytes count and Neutrophil adhesion assay in cyclophosphamide treated rats. The results indicate the potential protective effect of AME in cyclophosphamide induced bone marrow suppression in...
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