Posted by admin on Jan 31, 2019 in |
Congenital heart disease (CHD) is a defect in the heart or major blood vessels that are present in children at birth & CHD it occurs in approximately 1% of live births in developed countries. Infants and children with CHD exhibit a range of delays in weight gain and growth. Objective: To find out the relationship between the children with CHD nutritional status and their socio-demographic characteristics. Methodology: Non-probability (purposive) sample of (65) were selected of 225 children who visit the heart center during the period of conducting the pilot study, previously diagnosed with congenital heart disease. Results: The children with congenital heart disease have (32.3%) suffered from underweight by weight for age, a highly significant relationship between weight for age index and gender. (64.6%) of study sample suffered from wasting with weight for height, a significant high association between the premature baby ” is wasting” and children with CHD. (78.5%) Suffered from stunting with height for age. Almost half of the study sample suffered from malnourished (49.2%) by measuring...
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Posted by admin on Jan 31, 2019 in |
Japanese encephalitis is the most common arthropod-borne human encephalitis in the world. JEV clinical outcomes vary from complete recovery to recovery with neuropsychiatric sequelae to death. Contribution of T cells to the control and immunopathology of JEV infection has been reported in various studies. CD4+ T cells were found to be major T cells that has role in protection as well as affecting the clinical outcome in murine Japanese encephalitis model. Role of the CD4+ T cells subset in determining outcome of JEV infection is incompletely understood. Therefore, we sought to determine how quantitative difference in CD4+ T cell subsets influences JEV infection outcome. A total of 544 Acute Encephalitis Syndrome (AES) cases were admitted in ICU and AES ward of Kushinagar District Hospital during a period from Aug 2013 to Dec 2015. A diagnosis of JEV infection was based on clinical symptoms and anti-JEV IgM antibody in the acute phase cerebrospinal fluid (CSF) and serum samples measured by IgM antibody capture (MAC)-ELISA. Blood samples were drawn, and flow...
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Posted by admin on Jan 31, 2019 in |
Objective: To compare the routine biochemical and histological techniques with FTIR-ATR spectroscopic methods in diagnosing hyperlipidemia. Materials: Compositional changes in the serum and tissues reflects the healthy and pathological status of animals. FTIR-ATR was attempted as an additional tool for evaluating the composition in the serum as well as in tissues materials. To achieve this Wistar rats are administered with high cholesterol suspension with coconut oil orally for 30 days. Results: Hyperlipidemia achieved with oral feeding of cholesterol-rich diet (200 mg/dl) on rats with body weight of 180 ± 10.0 g led to a rapid progression of hyperlipidemia resulting might cause atherosclerosis. In blood, cholesterol level (269 ± 8.72), Triglyceride (194 ± 5.03), LDL (165 ± 5.10) increased and a decrease in the serum HDL level (39 ± 3.09) obtained in the cholesterol-rich fed hyperlipidemia was observed. FTIR- ATR spectral peaks were obtained (1165 cm-1 for ring vibration mode of C-O-H and C-O-C bonds cholesterol ester with phosphoric acid, 1742 cm-1 responsible for C=O group of cholesterol ester (HDL)...
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Posted by admin on Jan 31, 2019 in |
The rhizomes of Curcuma caesia Roxb. (Zingiberaceae) Are traditionally used in the treatment of various ailments and metabolic disorders like leucoderma, asthma, tumors, piles, bronchitis, etc. in Indian system of medicine. Considering the importance of natural products in modern phytomedicine, the antioxidant and ant mutagenic activities of C. caesia Roxb. rhizome extract and its fractions were evaluated. The antioxidant results indicate that the free radical-scavenging activity may be attributed to the high contents of phenolics and flavonoids with a higher reducing capacity. The IC50 values of in-vitro and ex-vivo antioxidant activities of Curcuma caesia was found for DPPH scavenging activity was 1.08 ± 0.06 μg/ml, nitric oxide scavenging activity was 37.50 ± 1.54 μg/ml, Hydroxyl radical scavenging activity was 10.08 ± 2.01 μg/ml, Superoxide Anion scavenging activity was 29.63 ± 2.07 μg/ml respectively. The in-vitro antimicrobial activity of different fractions obtained from the rhizome of Curcuma caesia was investigated against standard strain and clinical isolates of Staphylococcus aureus. The clinical isolates were found more sensitive for different fractions, than...
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Posted by admin on Jan 31, 2019 in |
Cardiovascular diseases (CVDs) cause 30% of deaths globally and are reported to be on the increase in sub-Saharan Africa. Medications prescribed for a CVD require a lifetime commitment. As a result patient must adhere to prescribed medication. However, prescription adherence is influenced to a large part by prescription knowledge. Although disease outcome is influenced by prescription knowledge, estimates of prescription knowledge and of factors that influence it are largely unknown in developing countries such as Kenya. The goal of the present study was to investigate factors that influence the level of prescription knowledge among patients with CVD at the Moi Teaching and Referral Hospital (MTRH). Specifically, the study determined the level of prescription knowledge, the association between socio-demographic characteristics of patients and their prescription knowledge, and whether prescribing clinicians explain prescriptions given to patients with CVD. The study used a cross-sectional study design with a sample size of 204. Data were collected using questionnaires. There was a significant difference (X² = 144.75, p = 0.000) in the frequencies between...
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