Posted by admin on Sep 30, 2024 in |
Arq-e-zeera, a distillate preparation of mainly Cuminum cyminum (Safed zeera), Bunium persicum (Shahi/kala zeera), Trachyspermum ammi (Ajwain) seeds, and Zingiber officinale (Adrak) rhizome isclinically used for declining obesity. Numerous trace elements, including calcium, magnesium, manganese, iron, zinc, and salt, are abundant in these herbs. These herbs have been observed to have diverse activities, notably antioxidant, antimicrobial, antidiabetic, hepatoprotective, anti-inflammatory and against gastrointestinal disorders. Major compounds of Arq-e-Zeera, as identified by GCMS and GC analysis, include thymol, limonene, terpinene, Cuminaldehyde, carvacrol, cymene, 1-phenyl-propanol, and 4-ethyl-3 non-5 yne, among other chemical components. Furthermore, because no or less evidence of their toxicity has been found in the literature, these are employed as aromatic ingredients and to enhance the taste, flavor, texture, and therapeutic benefits of many traditional cuisines. This review provides updated information on the morphological and taxonomical classification, chemical structures, experimental models, and methodologies employed in investigating the numerous activities and chemicals identified from the four primary constituents of...
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Posted by admin on Sep 30, 2024 in |
Introduction: Aedes mosquitoes are responsible for transmitting several life-threatening diseases worldwide, which poses a significant societal burden. It is crucial to control these mosquito vectors to prevent the transmission of diseases. In this regard the present work focused on phytochemical screening and larvicidal activity on the whole plant of Barleria cuspidate ethanolic extract. Methods: Ethanolic extract of Barleria cuspidata was prepared by successive extraction using the maceration method. The larvicidal activity of different concentrations (20 mg/ml, 40 mg/ml, 60 mg/ml, 80 mg/ml, and 100 mg/ml) was assessed against 4th instar Aedes aegypti. Mortality rates were recorded after 24 hrs and 48 hrs to evaluate the larvicidal activity against Aedes aegypti. Results: The phytochemical screening of Barleria cuspidata ethanolic extracts revealed the presence of Alkaloids, Saponins, Flavonoids, Steroids, and Tannins. At a concentration of 100 mg/ml, the extract demonstrated the highest inhibitory effect, with mortality rates of 84% and 93% observed at 24 and 48 hours respectively. In contrast, no mortality was observed in the control group, indicating that the observed effects were specifically due to the extract. The LC50...
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Posted by admin on Sep 30, 2024 in |
The aim of this study was the quantitative phytochemical screening of extracts obtained from the leaf, flower, and latex with antibacterial activity and antioxidant activity of Cascabela thevetia (C. thevetia). The Quantitative determinations of total flavonoid, carbohydrate, and polyphenol contents were accomplished by Folin-Ciocalteau, phenol-sulfuric acid, and AlCl3 methods. The in-vitro antioxidant activity was evaluated by the DPPH free radical scavenging activity method. All the samples were screened for antimicrobial activity against gram-positive (S. aureus, S. pneumonia) and gram-negative (E. coli and K. pneumoniae) bacterial strains by using the disc diffusion and well method followed by calculation of minimum bactericidal concentration (MBC). Phytoconstituents of different samples of C. thevetia in different solvents contain total polyphenol and carbohydrate content were highest at methanol flower extract 80.26 ± 0.86 and 178. 15 ± 3.15 µg GAC and GLU equivalent/mg of dry extracts weight respectively. But flavonoid content was methanol leaf extract 654.53 ± 2.08µg QAR equivalent/mg of dry extracts weight. Among them the lowest IC50 value was 82.84 performed by aqueous...
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Posted by admin on Sep 30, 2024 in |
Introduction: Pathogenic infections place a significant burden on the healthcare system since they are linked to high rates of morbidity and mortality. Successful therapy of these illnesses depends on an early diagnosis and a good antimicrobial resistance testing. Therefore, the goal of the current investigation was to assess aerobic bacteriological profile and antibiogram from a variety of sterile fluids. Material and Method: This observational study was carried out in the Department of Microbiology, Adesh Institute of Medical Science & Research Bathinda, Punjab from 20 September 2023 to 15 February 2024 obtaining the approval from Ethics Committee of Biomedical & Health Research, Adesh University. All the Body fluid samples were received in Bacteriology Laboratory from various departments. All body fluid samples are processed by Bact alert system. Positive samples were further subculture on blood agar and MacConkey agar. Gram Staining was done to identify gram-positive bacteria and gram-negative Bactria, further antimicrobial susceptibility was done by Vitek 2 compact system as per CLSI guidelines 2023. Results: A total of 288 body...
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Posted by admin on Sep 30, 2024 in |
Introduction: Flap surgeries can be followed by some complications due to the infection of the operating site. Sutures at the operating site can predispose to surgical site infections by harbouring the microorganisms due to their wicking action. Triclosan-coated antibacterial sutures can be used an effective substitute to traditional sutures due to its ability to reduce biofilm. Aim: This trial evaluates clinically and microbiologically the effectiveness of antibacterial coated sutures compared to non-coated ones. Materials and Methods: 20 sites in 10 systemically well patients were diagnosed with Stage III Periodontitis [2017 AAP Classification] and was allotted into group A and group B randomly in a split-mouth design for the research. Flap surgery was performed, and in Group A, triclosan-coated polyglycolic acid braided sutures were placed and in Group B non-coated polyglycolic acid braided sutures were placed. In both the groups, Visible Plaque Index (VPI) and total microbial colony count on the suture were assessed on the suture removal day. Healing Index (HI) was assessed on the 8th day and day...
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