Posted by admin on Sep 30, 2018 in |
The objective of the study was to assess the effect of Pharmaceutical care training on Knowledge, Attitude and Practices of Pharmacists from various settings. In this prospective interventional study, a validated Knowledge, Attitude and Practice questionnaire was administered, before and after an educational training to the pharmacists belonging to hospital, community and corporate settings of Pune district of Maharashtra. The Post-training impact on knowledge, attitude and practices was assessed by administering the same questionnaire after 3 months to the same set of pharmacists. The results were analyzed using paired ‘t’ test and simple descriptive analysis. A total of 446 pharmacists were enrolled in the study. In the post-educational intervention, the overall Knowledge scores of participants were found to have significantly increased from 177.40 ± 59.62 to 325.8 ± 76.11; a mean score with value of p= 0.0089, a significant improvement in Attitude from 302.40 ± 82.80 to 409.80 ± 22.90; a mean score with value of p = 0.0234 and improvement in Practice component was from 149.20 ± 53.03...
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Posted by admin on Sep 30, 2018 in |
A simple, selective, ingenuous, reasonable, speedy, Reverse Phase High Performance Liquid Chromatography (RP-HPLC) was developed for simultaneous estimation of neomycin and fluocinolone in its tablet dosage form. The separation was eluted using a mobile phase of buffer and methanol in the proportion of 50:50 a pumped at a flow rate of 1 ml/min besides 250 nm as a UV detection wavelength. The stationary phase used was column discovery 250 × 4.6 mm, 5m. The drug samples were eluted at a retention time of neomycin 2.403 min and fluocinolone 3.303 min. The proposed analysis was developed and validated based on ICH guidelines by taking into account the parameters such as precision, accuracy, linearity, specificity, robustness, limit of detection, limit of quantification and degradation studies. The developed RP-HPLC method proved to be stability indicating by the resolution of samples with their forced degradation studies. The designed method used for routine analysis of neomycin and fluocinolone in combined dosage form. For peak detection and purity confirmation PDA was used as a...
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Posted by admin on Sep 30, 2018 in |
Background: The quality of education offered by Pharmacy institutions in the country varies widely. There are only a few institutions which maintain internationally recognized standard. Aim: To assess the pharmacy student’s (Pharm. D) perception today, their course, curriculum, and facilities provided. Methods: A postal survey was conducted on the Pharm. D students in Tamil Nadu, India, affiliated to The TN Dr. MGR Medical University. Students were evaluated for the perception on their curriculum, education, facilities provided and perception about the practice of clinical pharmacy in India. Results: 412 students responded to questionnaire. Based on the evaluated questionnaire, the student’s perception towards pharmacy education and curriculum seems to be very poor and survey also revealed poor inclination towards pharmacy as a profession. Student’s perception on scope and contribution was found to be unsatisfactory. Student’s learning tools, teaching methods and evaluation system were found inexpressive to the pharmacy students. Therefore, there is a need to change such a wrong perception and poor inclination from the minds of pharmacy students by the...
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Posted by admin on Sep 30, 2018 in |
This research aimed to analyze the effect of vitamin B12 supplementation on vitamin B12 serum level and memorizing ability of preschool children. A community – randomized controlled trial of 29 preschool children (4-6 year) was conducted for six months. Subjects were divided into two groups, treatment group (received 10 mcg of vitamin B12 daily syrup) and control group (placebo). Serum vitamin B12 and memory levels of children were measured before and after the intervention. Result of research was after 6 months of vitamin B12 on supplementation prevalence of vitamin B12 deficiency decreased in treatment group from 26.7% to 0.0%, while in the control group increased from 21.4% to 28.6%. The mean of increasing serum vitamin B12 was significantly different among those groups (148 ± 110.9 pg/ml in the treatment group and 3.7 ± 12.8 pg/mL in the control group). Memorizing ability affected by vitamin B12 supplementation for overall children with relative risk (RR) was 19.5. Reviews of this research imply the important result of vitamin B12 supplementation on improving...
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Posted by admin on Sep 30, 2018 in |
An accurate, simple, new, precise, rugged and stability indicating method was developed for simultaneous estimation of sitagliptin and metformin HCl in tablets. The developed method was rapid and economic. The Chromatographic separation was achieved isocratically on a C-18 column by using ammonium acetate buffer (adjusted to pH 5.0 with glacial acetic acid): MeOH (60:40 v/v). Octane -1-sulfonic acid sodium salt was used as an ion pair agent. Flow rate of 1mL/min with dual wavelength UV detection (265nm for sitagliptin & 225 nm for metformin) was used. The retention times of metformin and sitagliptin are 2.398 min and 17.113min respectively. The developed method was specific and well separated from the impurities of both sitagliptin and metformin. The method is linear in a range of 50% to 150% for both sitaglitpin and metformin. The correlation coefficient was found to be r2= 0.9997 & 0.9998 for sitagliptin and metformin respectively. Both standard and test solutions proved to be stable for up to 48 h. Forced degradation study showed that the method is...
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