Posted by admin on Jun 30, 2018 in |
Diabetes mellitus is reaching potentially epidemic proportions in India. The level of morbidity and mortality due to diabetes and its potential complications are enormous and pose significant healthcare burdens on both families and society. In this study 400 blood serum samples were collected from various laboratories and diabetic centre in and around Tirupur, Tamil Nadu, India. Blood glucose level was estimated like Fasting Blood Glucose (FBG), Post Prandial Blood Glucose (PPBG), HbA1c and lipid content. Totally 215 (53.7%) samples were positive for diabetic. This study revealed that type 2 diabetic patients followed up in the diabetic center in Tirupur District, showed a high rate of chronic complications which often occurred in a mid age between 41 to 60 years and also hypertension and high cholesterol was not a major influence for diabetic complications. Numerous socio demographic and biological factors were significantly associated with the high rate of complications. Social and clinical factors significantly associated with high rate of complications were age between 41 to 60 years (74.87 %), male...
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Posted by admin on Jun 30, 2018 in |
The author has been proposed the precolumn derivatization method for the trace level quantification of cypionyl chloride in testosterone cypionate, it maybe potential impurity in the testosterone cypionate, it has to quantify in the testosterone drug Substance. The method development of cypionyl chloride has been started with gas chromatography with FID detector. The detection of cypionyl chloride was very poor and detection was less even for derivatization with 2-butanol in GC-FID detector. The GC-MS Electron impact ionization detector with derivatization by 2-butanol was developed and validated for trace level quantification of cypionyl chloride in Testosterone cypionate. The LOQ of this method was 1.7 ppm and the LOD was 0.6 ppm. The validation parameters were done against the ICH Q2 R1 guidelines. The precision, linearity, accuracy and solution stability was met the ICH Q2 R1...
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Posted by admin on Jun 30, 2018 in |
Lichens came as a consortium of two distinct and dissimilar components- the mycobiont and the phycobionts, which were defined as a composite organism. Lichen vegetation in India is dominated by more than 2500 species. Lichen secondary metabolites specially the phenolics, depsides and depsidones are unique in their origin and are found nowhere else. Much attention has been paid on the biological roles of lichen secondary substances in the recent past; which have been found to possess a lot of bioactivities, such as anti-tumor, antibacterial, antifungal, antiviral, anti-inflammatory and antioxidant activities. The present study aims on the bactericidal activity of lichen, Cladonia scabriuscula, collected from the Gopeshwar, Uttarakhand in the Western Himalayas. The 50% v/v ethanolic extract (CSE) extracted through cold extraction method was tested for its bactericidal potential against prevalent water borne pathogen and its antioxidant potential through CLSI protocol. The CSE was found active against E. coli and S. typhimurium with MIC 2.48 and 1.02 mg/ml respectively; while the FRSA IC50 was 0.625...
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Posted by admin on Jun 30, 2018 in |
Worldwide diabetic patients are very common. This paper studies spread of diabetes in human living in Lahore, Pakistan. Data is collected from two local hospitals of Lahore and TOPSIS is applied to draw the results of the study. The study points out the people who are more likely to have diabetes due to various parameters like age, weight, height, body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), urinary creatinine, albuminuria and albumin creatinine ratio (ACR)...
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Posted by admin on Jun 30, 2018 in |
The architecture of cocoons and the chemical compounds present in the cocoons play crucial role to provide protection of the pupae during metamorphosis. Insects spin a silk web as cocoon to facilitate protection and ensuring proper inner environment inside the cocoon during the metamorphosis. Such cocoons are equipped with a variety of chemical compounds which include antibacterial, antifungal, insecticidal and insect repellent etc. Tasar silk worms are wild silkworms grown on forest trees for their commercial value, are subject to harsh environmental conditions in comparison with domesticated Bombyx mori silk worms. In this study antimicrobial compounds were screened from Indian tropical wild tasar cocoons by Fourier transform infrared spectroscopy (FT-IR), Fourier transform-Raman spectroscopy (FT-Raman), Gas chromato-graphy- Mass spectrometry (GC-MS) and identified the chemical compounds by NIST05 MS Library. The wild cocoons possess active alcoholic and phenolic compounds, aromatic organic acids, alkaloids, fatty acids and their derivatives for various protective functions. This chemical defence strategy of wild cocoons was confirmed by evaluating the antimicrobial potential of methanolic extract of Antheraea...
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