Posted by admin on Feb 28, 2018 in |
Objectives: To compare the efficacy of ferrous calcium citrate with ferrous ascorbate on Hb levels in anaemic pregnant women. Method: In this observational study, patients receiving ferrous ascorbate with elemental iron 100 mg were allocated to group A and those receiving ferrous calcium citrate with elemental iron 50 mg allocated to group B. After recording the baseline data, their Hb levels, side effects at the end of each month were recorded. Results and discussion: Change in mean Hb levels from baseline to three months is 1.59 ± 0.74, 1.94 ±0.52 in group A and group B respectively with the p value ≤0.05. Group B did show statistically significant difference in terms of change in Hb among primi and multiparous women, contrast to group A. Conclusion: Study reveals that ferrous calcium citrate results in better increase in Hb levels and lesser proportion of side effects in contrast to ferrous...
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Posted by admin on Feb 28, 2018 in |
Bisphenol A is well known endocrine disturbing chemical. Evidence has demonstrated that exposure to certain levels can cause toxic effect in humans and laboratory animal models. Quercetin is consistently the most active of the flavonoids in experimental studies. The present investigation was an attempt to evaluate the effect of Bisphenol A on testis and its amelioration by quercetin. Inbred Swiss strain male albino mice were orally administered with BPA (80, 120 and 240 mg/kg body weight/day) for 45 Days. On the completion of treatment, animals were sacrificed, testis was isolated and used for evaluation of energy metabolism (SDH and ATPase activity) and phosphatases activity (ACP, ALP). The results revealed that oral administration of BPA for 45 days caused significant dose-dependent reduction in activities of ATPase and SDH. However, ACP and ALP activities were significantly dose-dependent increased in BPA treated mice. Oral administration of Quercetin (30, 60 and 90 mg/kg body weight/day) along with high dose of BPA (240 mg/kg body weight/day) for 45 days caused significant amelioration in all...
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Posted by admin on Feb 28, 2018 in |
In the proposed work, enhancement of anticancer potential of curcumin extracted from Curcuma longa Linn. by encapsulated in the silver nanoparticle. Curcumin was extracted from Curcuma longa by Soxhlet method. Curcumin is a kind of poly phenols which was widely used because of its medicinal application. Curcumin shows poor solubility and low absorption rate therefore its silver nanoparticles was formed to increase solubility, absorption as well as affectivity against tumor. Various analytical methods and assay such as Particle size, Zeta potential, Atomic Force Microscopy (AFM), Differential Scanning Colorimetric analysis (DSC), X-ray Diffraction (XRD) and Fourier Transform Infrared Spectroscopy (FTIR), Drug Release, Hemolytic toxicity study and In-vitro cytotoxicity study were employed for monitoring the formation of nanoparticles. Presence of silver nanoparticles with an average size of 17.98 nm was revealed by Atomic Force Microscopy and particle size analyzer and zeta potential may obtained -4.68 mV. The result of hemolytic toxicity was demonstrated that Cur-AgNPs shows lesser hemotoxicity in comparison with plain curcumin and Cur-AgNPs were able to release 93.15% curcumin...
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Posted by admin on Feb 28, 2018 in |
The aim of the present study is to evaluate the antifungal effect of Anvillea radiata and to test the storage efficiency of soft wheat by coating. Phytochemical screening conducted on the Anvillea radiata extracts revealed the presence of the elements has known medical and physiological activities. Our results show a correlation between the plant part, extract concentrations and mold species. In general, all the sensitivity curves show an increasing trend with more or less steep slopes depending on the mold strains and concentration. This action makes it possible to use the method of storage soft wheat by coating grains for increases the storage time and reduces the risk of alteration by...
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Posted by admin on Feb 28, 2018 in |
Thymoquinone (TQ) is the major active component of black seed essential oil which possess encouraging effects against cancer cells. The antitumor activities of TQ were verified in breast carcinoma in-vitro and in-vivo. Most of the times, the cellular responses to apoptosis, after TQ treatment, are evaluate by flow cytometry using annexin V-propidium iodide (PI) staining method. Although flow cytometry has become an important tool to study characteristics of individual cells but induction of auto fluorescence (AF) can decreases the technique sensitivity. In order to investigate the effect of TQ on AF induction, we assessed the fluorescence after TQ treatment. We present evidences suggesting that the change in AF is depend on cell type and TQ concentration. We show here, MDA-MB231 breast cancer cell line treated with different concentration of TQ exhibits elevated level of auto fluorescence (AF) when analyzed by flow cytometry. Consistent with this view, MCF-7 cells did not show any AF upon TQ treatment, in contrast to MDA-MB231. Finally, we presents data demonstrating that changes in AF...
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