Posted by admin on Feb 28, 2018 in |
Single cell protein is a protein extracted from cultured algae, yeasts, or bacteria and used as a substitute for protein-rich foods, especially in animal feeds or as dietary supplements. Many types of animal feeds contain single cell proteins. It can also be called biomass, bioprotein or microbial protein. The word single cell protein which was coined in the 1960 is considered to be appropriate since most of the microorganisms grow as single or filamentous individuals. Besides its high protein content (about 60 – 82% of dry cell weight), single cell protein also contains fats, carbohydrates, nucleic acids, Vitamins and minerals. According to various investigations on the fermentations of fruit juices, it has been reported that they could be used as feed-stocks for the production of single cell protein (SCP) based on their level of sugar and ability to support the growth of yeasts. Single cell proteins thus, are the dried cells of microorganisms such as yeast that could be grown in large-scale culture systems for use as protein for...
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Posted by admin on Feb 28, 2018 in |
Although NVP-BEZ235 and XAV-939 have been shown a promising result in the treatment of colorectal cancer (CRC), our data is little with regard to the effect of environmental cytokine on this drugs. In order to explore the reaction of CRC to this novel therapy, the current study proposes to investigate the inhibitory effect of NVP-BEZ235 and/or XAV-939 in CRC cells in combination with TGF-β as a tumor environmental cytokine to analyze their effect on cancer cell proliferation, cell death and expression of cancer promoting genes. The cells were treated with single or combination of NVP-BEZ235, XAV-939 and TGF-β. Cell viability was evaluated by MTT assay. Flow cytometry method was used to determine cellular death. Real-time PCR was utilized to identify the effect of treatments on expression of snail, slug, C-myc and notch1 genes. The results revealed that NVP-BEZ235 inhibited CRC cells proliferation and induced senescence cells more than XAV-939. Although, XAV-939 increased cellular death and inhibited senescence induction of CRC cells better than NVP-BEZ235. TGF-β pretreatment sensitizes CRC cells...
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Posted by admin on Feb 28, 2018 in |
“Soda” is one of the humors in the body which should be in normal level for being healthy. If “soda” increases in the body, some undesirable symptoms appear. In order to eliminate the excess “soda”, at first it should be maturated. There are different formulations in Iranian traditional medicine references as “Monzig-e-soda” which is a way of maturation of black bile. In one of the references, the aqueous extract of Cordia mixa, Glycyrrhiza glabra, Adiantum cappilus-veneris, Foeniculum vulgare, Fumaria spp, Lavandula angustifolia, Echium amoenum, Melissa officinalis and Ziziphus jujuba is prepared as decoction. In the present investigation, the capsule form of the plants was prepared and its stability was assessed. The mentioned species were mixed in ratio of 2.4:1.5:1:1:1:1:1:1:2, respectively and extracted with water (1:10) in 90 °C, 2h. The aqueous extract was dried and packaged in capsules 500 mg. In order to assess the stability of capsules, they were divided into two groups: group 1 were placed in 30 °C and room humidity for 12 months (long- term...
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Posted by admin on Feb 28, 2018 in |
Objective: The main objective of the present work was to analyze the therapeutic potential of various fractions of ethanolic extract of Tecomella undulata Seem. heartwood in streptozotocin – nicotinamide (STZ-NA) induced diabetes in experimental rats. Materials and methods: Diabetes was induced in the experimental rats by injecting nicotinamide and streptozotocin intraperitonealy at an interval of 15 minutes. The diabetic rats were then treated with standard drug; metformin and different fractions of 70% ethanolic extract of heartwood of Tecomella undulata for the 21 days. The animals were estimated for the different biochemical parameters which included liver function test, kidney function test and total lipid profile of experimental animals. Histopathological studies were also carried out on the liver and pancreas tissue sections. Results: All the fractions exhibited a reduced blood glucose level but the best results were revealed by acetone fraction as is indicated by statistical data. All fractions depicted a positive approach to normalize the altered biochemical parameters of kidney, liver and heart organs of diabetic animals. Thus it indicats...
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Posted by admin on Feb 28, 2018 in |
The plant Rouwolfia tetraphylla has been used traditionally as antihypertensive and has been proven scientifically to possess high antioxidant and hepato-protective activity. This study was designed to check the potential of medicinal plants in treatment of hypertension which will be helpful to reduce the side and adverse effect of allopathic antihypertensive drugs. During the experimental period, 1% sodium chloride solution was administered orally with drinking water for four weeks and DOCA – salt (20 mg/kg body weight) was injected subcutaneously to elevate the systolic, diastolic and mean arterial blood pressure. The rats were then treated with the methanolic extract of Rouwolfia tetraphylla and a significant decrease in the systolic pressure was recorded. Biochemical assays including serum urea, serum creatinine, triglycerides, cholesterol, blood glucose and serum protein were also performed to assist the hypothesis. The study thus, concludes the anti-hypertensive activity of Rouwolfia tetraphylla in the DOCA – salt hypertensive wister...
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