Posted by admin on Nov 30, 2017 in |
Zirconium tetrachloride was produced in a pilot plant fluidized bed reactor via the carbochlorination reaction of zirconia. Minitab software 17 was used for the design of experiment with response surface methodology (RSM) for both semi batch and continuous processes. The operating temperature (800-1200 °C), reaction time (30-90 min) and mean particle size (MPS) (70-130µm) were chosen as the range of operating conditions at semi-batch mode. Also, the ranges of operating variables at the continuous mode were chosen to be the operating temperature(1000-1400°C), chlorine concentration (3-5mol/m3) and mean particle size (MPS) (70-130µm). The coefficients of determination (R2) for semi-batch and continuous modes by RSM analysis were 99.54% and 99.94%, respectively. The optimal operating conditions was predicted to be the Cl2 concentration of 3mol/m3, temperature of 1380 °C and the mean particle size of 70µm in which the maximum chlorine conversion of 98.26% was obtained at continuous process. The optimum operating conditions for semi-batch process were found by using RSM modelling to be 1200°C, 90 min and 70 µm, in which...
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Posted by admin on Nov 30, 2017 in |
Pregnancy and childbirth have been an essential part of human existence for millennia, but unfortunately the experience has not been easy for all women. Although many pharmaceutical drugs are available but the potential of drugs to cause harm, exemplified by thalidomide in 1958 cannot be ignored. Therefore, many pharmaceutical drugs are not recommended for use during pregnancy either because of known or suspected problems or because not enough is known to say that they are safe. In this respect, herbal medicine is gaining popularity both in developing and developed countries because of their natural origin and relative safety with fewer side effects. This article briefly reviews some of those plants all over the world which are being used during pregnancy, childbirth and postpartum care. About 122 plants species belonging to different families were reviewed among which the most common were Asparagus racemosus (Liliaceae), Apium graveolens (Apiaceae), Rheum officinale (Polygonaaceae), Veratrum nigrum (Melanthiaceae). From the present studies it can be conclude that, herbal medicines can be used during pregnancy, childbirth...
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Posted by admin on Nov 30, 2017 in |
Siddha system of medicine is the ancient traditional medicine practiced all over Tamil Nadu. Siddha system is bestowed with various specialities of few which are Varmam, Pranayamam, Yoga and Kayakarpam. This system has a vast repository of internal and external medicines; Varmam is one among such therapies used to treat multiple ailments, especially related to musculoskeletal and neurological deficits. Varmam is the vital life energy points located in human body and was identified as 108 points by the Siddhars. Here the Varmam treatment for Azhalkeelvaayu (Osteoarthritis), one of the types of Keelvaayu mentioned in the Siddha Noi naadal book is evaluated in a small group of patients. Among the elderly knee Osteoarthritis is leading cause of chronic disability in developed countries. Osteoarthritis (OA) is the second most common rheumatologic problem and is most frequent joint disease with prevalence of 22% to 39% in India. A study was done on 30 clinically diagnosed patients of osteoarthritis (knee joint). Such patients who underwent Varmam therapy are observed and results are presented....
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Posted by admin on Nov 30, 2017 in |
Community pharmacists are well placed to contribute to reduction of premature deaths from cardiovascular disease by implementing risk assessment and reduction strategies. The objective of this study was to assess outcomes of pharmacist’s cardiovascular risk reduction intervention among high risk persons dwelling in a rural community. Cardiovascular risk reduction intervention was carried out among 45 high risk patients using a non-randomized before and after design. Blood pressure, total cholesterol, random blood sugar and BMI were measured. Intervention consisted of leaflet based patient education, referral to physician and provision of prescribed medications at no charge. Data were expressed as mean, standard deviation and 95% confidence interval. Differences between baseline and post intervention values were explored using paired t test. The primary outcome measure was change in cardiovascular risk category between baseline and end of study. The results show that there were significant differences in blood pressures at baseline vs. post-intervention, (184.74 ± 15.78 vs. 138.69 ± 13.57; P ˂ 0.001), and (102.17 ± 15.14 vs. 82.62 ± 9.45, P ˂...
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Posted by admin on Nov 30, 2017 in |
Objective: Newly designed antipsoriatic agents which are substituted series of analogues of flavonoids (kaempferol and quercetin) that belong to the subclass flavonols were subjected to (2D-QSAR) analysis using VLIFEMDS-QSARPro software with an intention to derive and understand the possible correlation of biological activity as dependent variable and other descriptors like molecular weight, XLogP values as independent variables. It can be concluded that the current study provides better insight for designing and chemical synthesis of more potent antipsoriatic agents. Methods: Several statistical regression expressions were obtained using variable selection method as simulated annealing coupled with various model building methods like partial least squares (PLS) Regression, multiple linear regression (MLR) etc. Results: For the analogues of both quercetin and kaempferol, a total of 9 QSAR models were generated, each using test set of 15 and training set of 45 similar compounds. The best QSAR model generated by PLS model building method for quercetin was model Q4 with correlation coefficient r2 of 0.9021 and significant cross validated correlation coefficient q2 of 0.5791.Similarly,...
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