Posted by admin on Nov 30, 2017 in |
Cinnamomum riparium Gamble belongs to the family Lauraceae is a red listed species by the International Union for Conservation of Nature (IUCN). It is a tree growing in evergreen forests and traditionally used for treating conditions like wound healing, fever, intestinal worms, headache, inflammations, menstrual problems etc. According to tribal’s, this activity is mainly due to the volatile oil present in it. But as per published reports much works have not been carried out so far using its volatile oil. Hence it was thought worth to do the research work on this plant. Berries were collected from Paniyeli poru, near Periyar river, Ernakulam District, latitude 10.1720° N and longitude76.5959° E Kerala, India. Berry essential oil was separated by steam distillation technique by using a Clevenger trap apparatus. Separated berry essential oil was used for evaluating the physical and chemical properties including therapeutic activity (antioxidant activity) using DPPH scavenging assays. The berry oil exhibited 76.45% of antioxidant activity. The oil was subjected to GC-MS analysis. The main constituents present in...
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Posted by admin on Nov 30, 2017 in |
Diclofenac sodium is a nonsteroidal anti-inflammatory drug (NSAIDs) with analgesic and antipyretic properties. Because of widespread use of this drug, quality control testing should be done for diclofenac marketed products to ensure safety; efficacy; accepted quality; rationality of use to protect public health. Quality of pharmaceuticals has been great concern of WHO. Drug cost needs to be reduced as health care costs continue to rise. Generic products need to be therapeutically equivalent to the brand innovator products. This can be achieved only when bioequivalent study is conducted to show whether a generic product is interchangeable with brand product or another generic product. In this study focus is given to evaluate and compare the quality of six different brands of enteric coated diclofenac sodium tablets marketed in Addis Ababa and also to study the different physicochemical properties of diclofenac sodium enteric coated tablets and to compare in vitro dissolution profile of six brands of diclofenac sodium delayed release...
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Posted by admin on Nov 30, 2017 in |
Agapanthus praecox Willd of the family Amaryllidaceae is widely used in South African traditional medicine to treat heart disease, paralysis, coughs, colds, chest pains and diarrhoea. The decoction is used to prevent pregnancy complications and argument labour. The study aims at determining the phytochemical constituents and investigating the potential toxicity of the solvent extracts of A. praecox. Quantitative phytochemical analysis was done using standard procedures and spectro-photometric techniques while the toxicity assessment was carried out with brine shrimp toxicity bioassay. The data were subjected to two way analysis of variance (ANOVA) followed by Tukey’s test. Methanol had the highest percentage yield of extract (16.2 %) while water (9.3 %) was the least. The quantities of tannins (335.23 mg g-1), phenols (91.11 mg g-1), proanthocyanidins (139.47 mg g-1), flavonoids (46.53 mg g-1) and flavanols (74.02 mg g-1) in acetone extract were significantly higher (p > 0.05) than in aqueous and methanolic extracts. Highest hatching success was recorded in aqueous extract (50.33%) and the lowest hatching success (p < 0.05) was...
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Posted by admin on Nov 30, 2017 in |
Zirconium tetrachloride was produced in a pilot plant fluidized bed reactor via the carbochlorination reaction of zirconia. Minitab software 17 was used for the design of experiment with response surface methodology (RSM) for both semi batch and continuous processes. The operating temperature (800-1200 °C), reaction time (30-90 min) and mean particle size (MPS) (70-130µm) were chosen as the range of operating conditions at semi-batch mode. Also, the ranges of operating variables at the continuous mode were chosen to be the operating temperature(1000-1400°C), chlorine concentration (3-5mol/m3) and mean particle size (MPS) (70-130µm). The coefficients of determination (R2) for semi-batch and continuous modes by RSM analysis were 99.54% and 99.94%, respectively. The optimal operating conditions was predicted to be the Cl2 concentration of 3mol/m3, temperature of 1380 °C and the mean particle size of 70µm in which the maximum chlorine conversion of 98.26% was obtained at continuous process. The optimum operating conditions for semi-batch process were found by using RSM modelling to be 1200°C, 90 min and 70 µm, in which...
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Posted by admin on Nov 30, 2017 in |
Pregnancy and childbirth have been an essential part of human existence for millennia, but unfortunately the experience has not been easy for all women. Although many pharmaceutical drugs are available but the potential of drugs to cause harm, exemplified by thalidomide in 1958 cannot be ignored. Therefore, many pharmaceutical drugs are not recommended for use during pregnancy either because of known or suspected problems or because not enough is known to say that they are safe. In this respect, herbal medicine is gaining popularity both in developing and developed countries because of their natural origin and relative safety with fewer side effects. This article briefly reviews some of those plants all over the world which are being used during pregnancy, childbirth and postpartum care. About 122 plants species belonging to different families were reviewed among which the most common were Asparagus racemosus (Liliaceae), Apium graveolens (Apiaceae), Rheum officinale (Polygonaaceae), Veratrum nigrum (Melanthiaceae). From the present studies it can be conclude that, herbal medicines can be used during pregnancy, childbirth...
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