Posted by admin on May 31, 2017 in |
The extraction of poly-β-hydroxybutyrate (PHB) and C-phycocyanin (C-PC) from Nostoc muscorum revealed that PHB yield after C-PC extraction was not found differ significantly as without C-PC extraction. Under photoautotrophic growth condition, the test cyanobacterium accumulates PHB and C-PC with a maximum yield of 40 and 57 mg l-1 respectively at the stationary phase, i.e. on day 21 of incubation. The most significant enhancement in C-PC yield up to 146 mg l-1 was recorded in 0.4 % fructose supplementation. High C-PC and PHB yield was observed in 0.4% fructose supplementation followed by 0.4% glucose supplementation. Here, in this study we show, that PHB yield after C-PC extraction was not affected significantly and C-PC yield was found enhanced under 0.4 % carbon source (fructose and glucose) supplementation. Significant Biomass and PHB yield depicted under supplementation of glucose, fructose, maltose and sucrose was due to boost in growth. Thus, present study demonstrates the extraction of both the products, i.e. PHB and C-PC is...
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Posted by admin on May 31, 2017 in |
Aims and Objectives: The present study was conducted to find out morphometry of thyroid gland in different age groups. Material and Methods: The study was conducted on 60 human thyroid glands in the Department of Anatomy, Pt. B. D. Sharma, PGIMS, Rohtak in North Indian population. Results: In present study, mean length of right and left lobe of thyroid gland was found to be 29.88±7.03 mm and 29.45±5.44 mm in Group A, 41.33±6.95 mm and 38.87±5.04 mm in Group B, 35.02±3.98 mm and 31.77±3.27 mm in Group C respectively. The mean width was observed as 18.76±4.23 mm and 20.77±6.01 mm in Group A, 24.13±4.77 mm and 22.47±2.72 mm in Group B, 21.54±2.05 mm and 20.72±2.53 mm in Group C respectively in right and left lobes. The mean thickness was 13.70±4.69 mm and 13.60±4.51 mm in Group A, 15.19±1.99 mm and 15.01±2.29 mm in Group B, 14.73±1.99 mm and 14.09±2.33 mm in Group C respectively in right and left lobes. The mean length and height of the isthmus of thyroid...
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Posted by admin on May 31, 2017 in |
Mental disorders are commonly occurring and often seriously impairing in many countries throughout the world. The total number of people suffering from anxiety or depression amount to 615 million, Close to 10% of the world’s population is affected. Chrysanthemum indicum is an ancient herbal medicine used as an anti-arthritic, anti-inflammatory and anti-anxiety in many Asian countries. The elevated plus-maze (EPM) and open field test has been most familiar tool in the investigation of the neurochemical transmission basis of anxiety, for testing anxiolytic drugs. The anxiolytic activities of Ethanolic and Chloroform extracts of Chrysanthemum indicum Linn flowers were evaluated using the elevated plus-maze (EPM) and Open field. The ethanolic extract results are suggestive of anxiolytic activity in dosages around 250 and 500 mg/kg, as expressed by elevation of the time spent on the open arms in the plus-maze; a decrease of freezing and increase of deambulation in the open field...
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Posted by admin on May 31, 2017 in |
The aim of the present studies is to evaluate the cytotoxic effects of newly formulated polymeric nanoparticles (ETP NP’s) of Escitalopram oxalate (ETP) on NB41A3 cell lines. They were made by ionic gelation method with particle size range between 60 – 115nm, showing spherical morphology. Moreover, zeta potential of the same was recorded as -1.89 ± 0.052 mV and its permeability release showed 98.45 ± 1.82 % in 24 hour. The cytotoxicity evaluation of the optimized formulation (A3) included qualitative method of cell morphology (microscopic and DAPI staining evaluation) and quantitative colorimetric assays like – neutral red (NRU), MTT and LDH. The results suggested that, in presence of ETP, there was a remarkable decrease in cell count whereas; ETP NP’s showed lesser cytotoxicity. performed. Further, in NRU membrane integrity was assessed and it showed 95.2 ± 0.83 % and 72.2 ± 0.56% of cell viability in ETP NP’s and ETP pure respectively. However, MTT assay summed up the cell viability up to 93.6 ± 0.68 % in ETP NP’s...
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Posted by admin on May 31, 2017 in |
The excessive exploitation of medicinal plants during recent years raises the issues regarding their quality, safety and efficacy. In this respect, there has been a rapid increase in the standardization of medicinal plants with therapeutic potential. In spite of the new techniques, identification and evaluation of plant drugs pharmacognostic study is more cheap and reliable. Abrus precatorius L. of family Fabaceae is native to India and is locally known as Rati. It is widely employed in traditional medicinal systems. The present investigation deals with the macroscopic and microscopic evaluation of the seeds of this species to record the parameters of diagnostic value. Macroscopic studies comprised of shape, size, taste, colour, odour etc. Microscopic studies were done by using trinocular microscope. Anatomy of the seed was studied by taking transverse sections. Such information will be used for further therapeutical and pharmacological evaluation of the species and will also help in maintaining the quality and purity of sample. Moreover, the study would also serve as a valuable tool in drug identification...
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