Posted by admin on Feb 28, 2017 in |
The studies on tree biomass for assessing carbon density in tropical forest ecosystem of central India was undertaken during 2009-11 in forest area of eight districts [Jabalpur, Seoni, Balaghat, Narsinghpur, Mandla, Dindori, Shahdol and Umaria] at 30 adopted representative sites at varying latitudes and longitudes. The annual rainfall of their study area was 1000-1600 mm. The soils of the study sites were alluvial, light to medium black as well as red and yellow with pH value ranging from 5.5 to 80. The study was confined in three vegetation type viz., teak mixed, salmixed and mixed forest. In the study new approach was adopted by using ground data as well remote sensing data to get an accurate estimate of vegetation carbon pool in the region. Among the 30 selected site ID, Tectona grandis was dominated at 10 side. The basal area and volume of tree species in forest study sites ranged between 0.8 to 169.68 m2/ha and 0.11 to 2, 31299.82 m3/ha. The maximum tree biomass/ha recorded for Shorea roubsta...
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Posted by admin on Feb 28, 2017 in |
The emergence of novel antibiotics against the upsurge of “Superbugs” is a breakthrough health intervention. Daptomycin has gained prominence as a novel antibiotic produced by Streptomyces roseosporus which has demonstrated a broad spectrum of activity in vitro against a wide range of aerobic and anaerobic gram-positive bacteria, including methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococci. The economic viability and large scale applicability of this high-value secondary metabolite is hampered by its poor production and tedious growth of S.roseosporus. The present study aims at strategic improvement of Daptomycin yield through reusability of the producer strain by its immobilization onto various non-conventional support matrices. Sufficient void volume, permeability, and cost effectiveness prompted the use of ultra porous refractory brick and ceramic foam for the immobilization of S.roseosporus. The surface area and porosity of the materials were characterized by BET surface analysis. Morphological transformations of the microbial cells were observed microscopically over the time. The cell mass adhered to the carrier was determined using SEM. The repeated use of immobilized cells led to...
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Posted by admin on Feb 28, 2017 in |
The objective of the study to formulate and evaluate of pulsatile drug delivery containing combination of domperidone and paracetamol for the treatment of migraine which is used to deliver the drug at specific time as per pathophysiological need of the disease and improvement of therapeutic efficacy and patient compliance. Domperidone and paracetamol in the core tablet was formulated with different concentration of superdisintegrants and microcrystalline cellulose, an outer shell tablet which is formulated with different weight ratios of ethyl cellulose (EC) and hydroxyl propyl methylcellulose (HPMC). The effects of the formulation of core tablet and outer shell of press coated tablets; on drug release and the lag time were investigated. The formulation was optimized based on acceptable tablet properties and in vitro drug release. The release profile of press coated tablet exhibited a lag time dependent upon the amount of HPMC K15 and EC in compression coating, followed by burst release. The optimized batch PRT3 gave a lag time of 6.1 h and drug release of 98.67% and 92.56%...
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Posted by admin on Feb 28, 2017 in |
Vernonia polyanthes Less. (Asteraceae) is a medicinal plant that has been broadly used in Brazil for the treatment of inflammation and cutaneous damages. The present study evaluated the phytochemical contents and the antioxidant and topical anti-inflammatory activities of the V. polyanthes branches. Dried and powdered of V. polyanthes branches were exhaustively extracted with ethanol by static maceration followed by partition to obtain the hexane, dichloromethane, ethyl acetate, and butanol fractions. Phytochemical screening and the total phenolic and flavonoid contents were determined using chemical reactions and spectrophotometry, respectively. The antioxidant activity was evaluated by DPPH, reducing power of Fe+3 and β-carotene/linoleic acid assays. The topical anti-inflammatory effects of the ethanol extract (EEVPB) and ethyl acetate fraction (EFVPB) were investigated in Croton oil-, arachidonic acid-, and phenol-induced ear edema models. Tannins, flavonoids, coumarins, terpenoids and steroids, saponins and alkaloids were detected in the ethanol extract and/or fractions. In these samples, the total phenolic and flavonoid contents varied from 0.65 ± 0.07 to 12.58 ± 0.67 g/100 g and 0.15 ± 0.02...
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Posted by admin on Feb 28, 2017 in |
DM is characterized by insulin resistance and dyslipidemia, in particular, high levels of total cholesterol, triglycerides and LDL, and low levels of HDL-C, wich confer increased risk for CAD. Our study aimed to evaluate lipid profile in type 2 diabetic (T2DM) patients with coronary artery disease (CAD) in Tunisian population. Plasma levels of lipid profile variables were determined in 148 CAD patients with T2DM and in 159 patients with only CAD. Severity of CAD was quantified according to the prevalence of multivessel disease and the degree of coronary stenosis. Our results didn’t show any significant differences between diabetic and non diabetic patients in lipid profile variables. We didn’t found significant differences between the number of vessel disease and the extent of coronary stenosis, and lipid variables levels potentially reflecting the absence of a relationship between lipid profile and the severity of CAD. Using the receiver operating characteristic (ROC) curve that included all these variables, TG was found to be the single most powerful predictor of the severity of coronary...
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