Posted by admin on Mar 1, 2016 in |
Ropivacaine is a promising drug for subarachnoid block because of its lower cardiotoxic and neurotoxic potential, but onset and duration of anaesthesia is also low and motor block is often insufficient which may lead to use of its higher doses. The aim of this randomized double-blinded study was to see whether the addition of small dose clonidine to small dose ropivacaine for spinal anesthesia prolonged the duration of postoperative analgesia while minimizing the side effects associated with higher doses of ropivacaine. We randomized 60 patients to 2 groups receiving intrathecal isobaric ropivacaine 18 mg (2.4 ml) combined with normal saline (Group R) or clonidine 30 μg (Group RC); all solutions were diluted with saline to 2.6 ml. We compared block characterstics, hemodynamic changes, post-operative analgesia and adverse effects of both the groups. Results showed that clonidine not only significantly reduced the onset time both of sensory and motor block, but also prolonged the duration. Hypotension and bradycardia was more with clonidine group during first hour. The addition of clonidine...
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Posted by admin on Mar 1, 2016 in |
Roghan-e-Narjeel (coconut oil) is extracted from dried Maghz-e-Narjeel (coconut kernels) which is derived from coconut (Cocosnucifera L.) tree. It is used extensively in tropical countries especially India, Srilanka and Philippines. The oil contains 92% of saturates consisting of medium chain fatty acids in the form of triglycerides containing lauric acid in large amount, and about 8% of unsaturates consisting of oleic and linoleic acids as triglycerides. The oil is colourless and has odour typical of the coconuts. It plays an important role in the treatment of ischemic heart disease, infections (viral, bacterial, fungal, protozoal), wounds and obesity. These effects of oil can be attributed to the presence of lauric acid, capric acid and caprylic acid. The aim of this review paper is to highlight the physico-chemical and pharmacological properties of Roghan-e-Narjeel (coconut oil) according to modern as well as unani...
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Posted by admin on Mar 1, 2016 in |
The adverse drug reaction (ADR) programme in India, targeted all healthcare professionals to report the ADRs, however the response is very limited. The ADR reporting is much concentrated to hospital settings and the community pharmacies are unaware of this change. This study was conducted to assess the attitude, knowledge and behaviour of community pharmacists to ADR related aspects. A prospective study carried out over six months, self-prepared validated questionnaire was used. Awareness programme was conducted and a feedback questionnaire was provided. Improvement was seen after awareness programme. The response rate obtained was 93.7%. Pharmacist realizes the benefit a patient can obtain if an ADR is reported and some had noticed ADR. Few pharmacists knew about Central Drugs Standard Control Organisation (CDSCO) as a centre for reporting ADRs. Majority of pharmacists would direct the patients to the physician, in case of occurrences of ADR. According to 26.67% of the pharmacists in the study, busy schedule is considered as a vital factor for under-reporting an ADR.86.67% claimed that the application of...
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Posted by admin on Mar 1, 2016 in |
Cancer is the abandoned growth of cells that invade and cause damage to surrounding tissue. Oral cancer appears as a growth or uncomfortable in the mouth that does not go away. Oral cancer, which includes cancers of the lips, tongue, cheeks, floor of the mouth, hard and soft palate, sinuses, and pharynx (throat). Tabocco and alcohol are recognized as the foremost risk factor for this oral cancer. HER2 (human epidermal growth factor 2) is one of the protein that plays a vital role in the growth of oral cancer. Limonia acidissima is widely known as wood apple against oral cancer an in-silico approach. The compounds of wood apple showed their anticancer properties against HER2 protein which could be used for further...
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Posted by admin on Mar 1, 2016 in |
An ethno-medicinal survey was undertaken in Bharai village of Kullu district in Himachal Pradesh to collect the information on the use of medicinal plants for the various diseases rampant in the area through questionnaire and personal interviews of the traditional health healers/rural people The investigation reveals that 20 plants belonging to the 16 different families are utilized by local health healers/rural people in traditional phytotherapy. This study also reveals that many people of this region still continue to rely on traditional medicine for their primary health care. There is a little documentation of ethno-medicinal knowledge was carried out in this region. In addition, several wild medicinal plants are declining in number due to destruction and unscientific collection of plants from forests. Hence there is an urgent need for exploration and documentation of the traditional knowledge in order to conserve the local ethno-medicinal plants. Details of medicinal plants are described alphabetically with their botanical name, family, local name, part used, disease/ailment and ethno medicinal...
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