Posted by admin on Mar 1, 2016 in |
Cancer is the abandoned growth of cells that invade and cause damage to surrounding tissue. Oral cancer appears as a growth or uncomfortable in the mouth that does not go away. Oral cancer, which includes cancers of the lips, tongue, cheeks, floor of the mouth, hard and soft palate, sinuses, and pharynx (throat). Tabocco and alcohol are recognized as the foremost risk factor for this oral cancer. HER2 (human epidermal growth factor 2) is one of the protein that plays a vital role in the growth of oral cancer. Limonia acidissima is widely known as wood apple against oral cancer an in-silico approach. The compounds of wood apple showed their anticancer properties against HER2 protein which could be used for further...
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Posted by admin on Mar 1, 2016 in |
An ethno-medicinal survey was undertaken in Bharai village of Kullu district in Himachal Pradesh to collect the information on the use of medicinal plants for the various diseases rampant in the area through questionnaire and personal interviews of the traditional health healers/rural people The investigation reveals that 20 plants belonging to the 16 different families are utilized by local health healers/rural people in traditional phytotherapy. This study also reveals that many people of this region still continue to rely on traditional medicine for their primary health care. There is a little documentation of ethno-medicinal knowledge was carried out in this region. In addition, several wild medicinal plants are declining in number due to destruction and unscientific collection of plants from forests. Hence there is an urgent need for exploration and documentation of the traditional knowledge in order to conserve the local ethno-medicinal plants. Details of medicinal plants are described alphabetically with their botanical name, family, local name, part used, disease/ailment and ethno medicinal...
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Posted by admin on Mar 1, 2016 in |
Hypothyroidism is a metabolic disorder, which results in slower rate of metabolism leading to life threatening medical conditions like diabetes and other complications. This study aims to analyze the prevalence of hypothyroidism and its co-morbidities in relation to the causes and risk factors in patients undergoing levothyroxine therapy and to know the adherence level of prescribers to the Thyroid Dysfunction and Dyslipidemia Guidelines of Indian Thyroid Society. Methods: This was a cross-sectional, observational, questionnaire-based, single visit study, which included adult patients who were on levothyroxine treatment for at least three months prior to enrolment. Demographic details, data pertaining to etiology of hypothyroidism, the dose of thyroxine used, comorbid conditions, and concomitant medications used were also documented. Compliance to Thyroid Dysfunction and Dyslipidemia Guidelines of Indian Thyroid Society was assessed and documented. Results 32% of the study population suffered from primary hypothyroidism. It was also found out that levothyroxine was given along with so many other medication classes with cardiovascular system drugs being the most prescribed medications. Regarding adherence to...
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Posted by admin on Mar 1, 2016 in |
The present study was concerned with analysis of the chemical constituents of essential oil of Citrus karna fruit peels by GC-MS technique and also its antibacterial activity against some pathogenic bacteria. The essential oil was extracted from fruit peels by steam distillation using Clevenger’s type apparatus. GC-MS analysis of essential oil showed presence of D-limonene and β-pinene as the major constituents. The antibacterial activity was detected by agar well diffusion method against Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa and Staphyloceceus aureus. The zones of inhibitions obtained were recorded and analyzed against standard control of Ampicillin. The essential oil showed higher antibacterial activity of 18.0 mm against P.aeruginosa and least antibacterial activity of 13mm against B. subtilis. The MIC of the essential oil on the susceptible bacterial isolates was between 111-333μg/ml. Present study concludes that essential oil from fruit peels of Citrus karna have a broad spectrum antibacterial activity against human...
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Posted by admin on Mar 1, 2016 in |
Herbal medicines have been widely utilized as effective remedies for the prevention and treatment of multiple health conditions for centuries by almost every known culture. Leptadenia reticulata belonging to the family Asclepiadaceae is an important medicinal plant which is used for various ailments. In the present study, an attempt was made to study the wound healing activity of aqueous extract of Leptadenia reticulata (AELR) using excision and burn wound models. In each model, animals were divided into three groups (n=6). Group I served as disease control group, received gel base, group II received AELR gel 10% and group III served as standard and received povidone-iodine 10% ointment. AELR gel 10% showed a significant (P<0.01) in both excision and burn wound models, which was comparable with the standard povidone iodine 10% ointment. Wound healing activity was also confirmed by histopathological studies. The present study suggested that topical application of aqueous extract of Leptadenia reticulata gel 10% plays an important role in wound healing activity. These finding could justify the inclusion...
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